Evaluating the predictive potential of Th1 (IFN-γ+CD4+)/CD4+ in rapidly progressive amyotrophic lateral sclerosis [0.03%]
快速进展性肌萎缩侧索硬化中Th1(IFN-γ+CD4+)/CD4+的预测价值评估
Jiahui Zhu,Yuechen Zhang,Shuqi Hu et al.
Jiahui Zhu et al.
Background: Th1 (IFN-γ+CD4+)/CD4+ cells exacerbate the release of pro-inflammatory cytokines, contributing to neuronal death. It is proposed that the peripheral immune system plays a pivotal role in the pathophysiology o...
Longitudinal decline in striatal DAT binding in LRRK2 Parkinson's disease: connections with CSF α-synuclein seeding activity [0.03%]
LRRK2帕金森病黑质多巴胺转运蛋白纵向下降:与脑脊液α-突触核蛋白致病性关系
Jing Wang,Xixi Sun,Yunfei Yin et al.
Jing Wang et al.
Objective: Parkinson's disease (PD) associated with mutations in the LRRK2 gene exhibits considerable pathological heterogeneity and may not present with Lewy body pathology. The α-Syn seed amplification assay (SAA) perf...
Amygdala-predominant Lewy bodies associate with cognitive decline and amygdala atrophy in Alzheimer's disease neuropathological change [0.03%]
以杏仁核为主的路易体与阿尔茨海默病神经病理改变相关的认知下降和杏仁核萎缩有关
Francisco C Almeida,Alexandra Santos,Tiago Jesus et al.
Francisco C Almeida et al.
Introduction: Amygdala-predominant Lewy body (LB) pathology occurs frequently in association with advanced Alzheimer's disease (AD). Its clinical significance is not yet fully clarified. We investigated the influence of a...
Vertebral artery compression syndrome: dual insights from angiography and video-oculography [0.03%]
椎动脉压迫综合征:来自血管造影和视频眼震图的双重认识
David Hale,Jing Tian,Caline Azzi et al.
David Hale et al.
Impact of spontaneous recanalization of occlusive cervical artery dissection on risk of stroke [0.03%]
颅外段颈内动脉夹层自然再通与缺血性卒中风险的关系
Lukas Mayer-Suess,Josefin E Kaufmann,Lukas Scherer et al.
Lukas Mayer-Suess et al.
Introduction: Occlusive cervical artery dissection (CeAD) is associated with worse patient outcome. The net clinical benefit of acute revascularization measures has to be weighed against the likelihood of spontaneous reca...
Correlation between metabolism and neuroinflammation of astrocytes in drug-resistant epilepsy [0.03%]
难治性癫痫中星形胶质细胞代谢与神经炎症的相关性研究
Xiao-Xiao Yu,Da Xu,Shuang Chen et al.
Xiao-Xiao Yu et al.
Epilepsy is a chronic neurological disorder. Although anti-seizure medications (ASMs) are currently primary treatment for epilepsy, about one-third of patients develop drug resistant epilepsy (DRE). Relevant studies have found that astrocyt...
Efficacy and safety of respiratory strength and endurance training in patients with myotonic dystrophy type 1 (DM1): a randomized controlled trial [0.03%]
肌营养不良症1型(DM1)患者呼吸力量和耐力训练的有效性和安全性:一项随机对照试验
Stephan Wenninger,Eva Heidsieck,Corinna Wirner-Piotrowski et al.
Stephan Wenninger et al.
Background: Myotonic dystrophy type 1 (DM1) is a multisystem disorder characterized by progressive muscle weakness, including the respiratory muscles, which often leads to ventilatory insufficiency. Despite its clinical r...
Randomized Controlled Trial
Journal of neurology. 2025 Sep 11;272(9):626. DOI:10.1007/s00415-025-13362-z 2025
Management of hypersensitivity in a patient with late-onset Pompe disease experiencing recurrent infusion-related reactions [0.03%]
庞贝病晚期发作的患者出现反复输液相关反应的过敏管理
Daniel H Mendelsohn,Natalia Garcia-Angarita,Andreas Hahn et al.
Daniel H Mendelsohn et al.
Autoimmune encephalitis with Anti-mGluR1 antibodies: a comprehensive review [0.03%]
抗mGluR1抗体相关自身免疫性脑炎综合述评
Yun Chen,Lisha Xie,Hongmei Cui et al.
Yun Chen et al.
Anti-mGluR1 encephalitis is a rare autoimmune disorder manifesting with cerebellar syndrome with varying levels of severity. However, limited data exist regarding the clinical features and treatment strategies for patients suffering from en...
Wartime stress and relapse risk in people with multiple sclerosis: a prospective cohort study [0.03%]
一项针对多发性硬化症患者的前瞻性队列研究:战争压力与复发风险
Roy Aloni,Carmit Dror,Tamar Barazani et al.
Roy Aloni et al.
Introduction: Psychological stress has been proposed as a trigger for disease activity in multiple sclerosis (MS), but findings have been inconsistent. While prior research has focused largely on chronic stressors, little...