[18F]THK5351 uptake in multiple system atrophy compared with other parkinsonian disorders [0.03%]
多系统萎缩与其它帕金森氏病的THK5351摄取情况比较研究
Yoshihiko Horimoto,Emi Hayashi,Yoshihiro Ito et al.
Yoshihiko Horimoto et al.
Background: The pathological processes in the early stages of multiple system atrophy (MSA) are still incompletely understood. Moreover, early-stage MSA is difficult to diagnose. ...
Comparative Study
Journal of neurology. 2025 Sep 24;272(10):650. DOI:10.1007/s00415-025-13389-2 2025
Effect of aging on biomarkers and clinical profile in Parkinson's disease [0.03%]
衰老对帕金森病生物标志物和临床特征的影响
Giulia Di Lazzaro,Federico Paolini Paoletti,Giovanni Bellomo et al.
Giulia Di Lazzaro et al.
Background: Parkinson's disease (PD) has different progression rates and disease characteristics according to age of onset, the younger being less cognitively affected and experiencing more motor fluctuations. We explored...
The impact of CGRP monoclonal antibodies on cytokine expression in chronic migraine: a cohort study [0.03%]
降钙素基因相关肽单克隆抗体对慢性偏头痛细胞因子表达的影响：队列研究
Jason C Ray,Stuart McDonald,Marian Todaro et al.
Jason C Ray et al.
Background: Calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs) are an effective preventative therapy for migraine; however, there have been rare reports of possible inflammatory complications. The primary o...
Cognition, FDG metabolism, and amyloid accumulation in relation to intracranial arachnoid cysts [0.03%]
脑池液囊与认知、FDG代谢及淀粉样蛋白沉积的关系研究
Victoria Emilie Neesgaard,Johanne Asperud Thomsen,Jette Stokholm Pedersen et al.
Victoria Emilie Neesgaard et al.
Background: Though traditionally regarded as harmless, incidental findings, recent literature indicates neuropsychological symptoms associated with intracranial arachnoid cysts (AC). Pathogenesis is unknown, but compressi...
Widespread and progressive brain atrophy is a common feature in patients with mitochondrial disease [0.03%]
线粒体病患者中广泛且进行性的脑萎缩是一种常见特征
Nora Mickelsson,Jussi Hirvonen,Mika H Martikainen
Nora Mickelsson
Background: Primary mitochondrial diseases comprise a group of inherited disorders that frequently affect the central nervous system. Previous studies have reported brain imaging findings commonly associated with mitochon...
Observational Study
Journal of neurology. 2025 Sep 23;272(10):648. DOI:10.1007/s00415-025-13354-z 2025
Effects of cognitive rehabilitation and exercise on brain structure in progressive multiple sclerosis: results from the CogEx trial [0.03%]
认知康复和锻炼对进行性多发性硬化症脑结构的影响：来自CogEx试验的结果
Francesco Romanò,Maria A Rocca,Elisabetta Pagani et al.
Francesco Romanò et al.
Background: We previously showed increased cortical grey matter (GM) volume in CogEx trial participants who performed cognitive rehabilitation (CR). Here, we explore combined CR and aerobic exercise (EX) effects on region...
Randomized Controlled Trial
Journal of neurology. 2025 Sep 23;272(10):645. DOI:10.1007/s00415-025-13382-9 2025
Letter to editors regarding "Serological analysis of gluten‑related antibodies in idiopathic neuropathies and cerebellar ataxia" [0.03%]
关于“自身免疫性多发神经病和小脑共济失调患者相关抗体的血清学分析”的来信
Iain D Croall,Nigel Hoggard,Richard A Grunewald et al.
Iain D Croall et al.
Olfactory identification impairment in cerebral small-vessel disease indicates cognitive network disconnection and predicts accelerated cognitive decline [0.03%]
脑小血管病的嗅觉识别障碍表明认知网络脱节并预测认知能力加速下降
Xiaoshu Fu,Bo Xie,Ludi Li et al.
Xiaoshu Fu et al.
Background: Olfactory identification impairment is a well-established early screening index for cognitive decline in neurodegenerative disorders. However, whether this simple sensory test can similarly detect or predict c...
Neuroanatomical normative modelling in frontotemporal lobar degeneration: higher heterogeneity in the behavioural variant [0.03%]
行为变体额颞叶痴呆的神经解剖学正常值建模：更高的异质性
Srijan Konwar,Nikolett Hunyadvari,Annalena Venneri et al.
Srijan Konwar et al.
Introduction: Frontotemporal lobar degeneration (FTLD) includes heterogenous diseases: behavioural variant frontotemporal dementia (bvFTD), primary progressive aphasias (PPA), progressive supranuclear palsy (PSP) and cort...
Kappa free light chain index as a diagnostic and prognostic biomarker in multiple sclerosis [0.03%]
κ型自由轻链指数作为诊断和预测多发性硬化症生物标志物的作用
Luis Moreno-Navarro,Sergio Mora-Diaz,Lourdes Ruiz-Escribano-Menchen et al.
Luis Moreno-Navarro et al.
Background: The proposed 2024 McDonald criteria incorporate the kappa free light chain (KFLC) index as an additional biomarker in multiple sclerosis (MS) diagnosis. Emerging evidence suggests that a high KFLC index may re...