Video head impulse test differentiates RFC1-CANVAS, FGF14-SCA27B, and idiopathic late-onset cerebellar ataxias [0.03%]
视频头脉冲试验可鉴别RFC1-CANVAS、FGF14-SCA27B和特发性晚发型小脑共济失调
Leonardo E Ariello,Daniel R Gold,Jennifer L Millar et al.
Leonardo E Ariello et al.
Background: RFC1-related CANVAS and FGF14-related SCA27B are recently recognized genetic causes of late-onset cerebellar ataxia (LOCA). Despite advances in genetic testing, most panels do not detect these intronic repeat ...
Critical demyelinating lesions in progressive multiple sclerosis: a prospective observational study [0.03%]
多发性硬化病程中关键脱髓鞘病变的前瞻性观察研究
Rowaid Ahmad,Caitlin S Jackson-Tarlton,Eoin P Flanagan et al.
Rowaid Ahmad et al.
Background and objective: Critical demyelinating lesions are individual lesions anatomically associated with progressive motor impairment initially described in highly selected cohorts with demyelinating disease. We aim t...
Observational Study
Journal of neurology. 2025 Oct 6;272(10):677. DOI:10.1007/s00415-025-13322-7 2025
The post-ABI effect-long-term impact of aging on participation after acquired brain injury [0.03%]
脑卒中后ABI的影响—获得性脑损伤后的长期老化对参与度的影响
Nikki S Thüss,Heleen M den Hertog,Coen A M van Bennekom et al.
Nikki S Thüss et al.
Introduction: Patients with a history of acute Acquired Brain Injury (ABI), including traumatic brain injury and stroke, will encounter the consequences of aging and its concomitant cognitive decline, which might result i...
Observational Study
Journal of neurology. 2025 Oct 6;272(10):675. DOI:10.1007/s00415-025-13423-3 2025
Alpha-internexin as a brain-specific neurodegeneration marker: development and validation of a novel CSF assay [0.03%]
α-Internexin作为脑特异性神经退行性病变标志物：新型CSF检测方法的建立与验证
Francisco J Meda,Anna Dittrich,Ingmar Skoog et al.
Francisco J Meda et al.
Background: Alpha-internexin (AINX) is a type IV intermediate filament alongside the neurofilament triplet proteins and periferin. Despite its homologies, the key difference is that AINX is central nervous system-specific...
The Sternbergers: Ludwig (1921-2008) and Nancy (1938-2014) [0.03%]
斯特恩伯格夫妇（Ludwig 1921-2008；Nancy 1938-2014）
Lazaros C Triarhou
Lazaros C Triarhou
Alberto Arturo Vergani
Alberto Arturo Vergani
Idiopathic intracranial hypertension and Ehlers-Danlos syndrome: a case series [0.03%]
特发性颅内高压和埃勒斯-丹洛斯综合征的病例系列研究
Isha V Ingle,David F Santos Malave,Gabrielle Bonhomme
Isha V Ingle
Background: Ehlers Danlos syndrome (EDS) is a group of 13 heritable connective tissue disorders with various ophthalmic manifestations. Idiopathic intracranial hypertension (IIH) is the presence of raised intracranial pre...
Idiopathic intracranial hypertension and Ehlers-Danlos syndrome: a case series [0.03%]
特发性颅内高压和埃勒斯-丹洛斯综合征的病例系列研究
Isha V Ingle,David F Santos Malave,Gabrielle Bonhomme
Isha V Ingle
Background: Ehlers Danlos syndrome (EDS) is a group of 13 heritable connective tissue disorders with various ophthalmic manifestations. Idiopathic intracranial hypertension (IIH) is the presence of raised intracranial pre...
Brain age as an accurate biomarker of preclinical cognitive decline: evidence from a 12-year longitudinal study [0.03%]
基于12年纵向研究的证据：脑年龄是前临床认知下降的准确生物标志物吗？
Odelia Elkana,Iman Beheshti;Alzheimer’s Disease Neuroimaging Initiative
Odelia Elkana
Cognitive decline in older adults, particularly during the preclinical stages of Alzheimer's disease (AD), presents a critical opportunity for early detection and intervention. While T1-weighted MRI is widely used in AD research, its capaci...
Brain age as an accurate biomarker of preclinical cognitive decline: evidence from a 12-year longitudinal study [0.03%]
基于12年纵向研究的证据：脑年龄作为临床前认知衰退的准确生物标志物
Odelia Elkana,Iman Beheshti;Alzheimer’s Disease Neuroimaging Initiative
Odelia Elkana
Cognitive decline in older adults, particularly during the preclinical stages of Alzheimer's disease (AD), presents a critical opportunity for early detection and intervention. While T1-weighted MRI is widely used in AD research, its capaci...