Sleep disorders and the risk of cognitive decline or dementia: an updated systematic review and meta-analysis of longitudinal studies [0.03%]
睡眠障碍与认知功能下降或痴呆风险的关系:纵向研究的系统综述和meta分析更新结果
Jinhuan Zhang,Juan Ou,Xingying Lu et al.
Jinhuan Zhang et al.
Background: The evidence on the relationship between sleep disorders and the risk of cognitive decline or dementia remains inconsistent. Objectives: ...
Lazaros C Triarhou
Lazaros C Triarhou
Thrombolysis-to-recanalization time and clinical outcomes in large-vessel occlusion patients with successful recanalization [0.03%]
成功再通的大血管闭塞患者溶栓至再通时间和临床转归之间的关系
Chang Cui,Jing Qiu,Yong-Gang Zhao et al.
Chang Cui et al.
Objective: The benefit of intravenous thrombolysis (IVT) before endovascular treatment (EVT) in patients with anterior circulation large-vessel occlusion (LVO) remains unclear. This study aimed to determine whether thromb...
Self-administration of rozanolixizumab via manual push and infusion pump methods in patients with generalised myasthenia gravis: a randomised, phase 3, open-label, crossover study [0.03%]
通用型重症肌无力患者手动推注和输液泵注射rozanolixizumab的自我管理:一项随机、3期、开放标签、交叉试验
Vera Bril,Carlo Antozzi,Tomasz Berkowicz et al.
Vera Bril et al.
Background: The phase 3, open-label, randomised, crossover MG0020 study investigated rozanolixizumab self-administration, efficacy, and safety in patients with generalised myasthenia gravis (gMG) using infusion pump and m...
Clinical Trial
Journal of neurology. 2025 Oct 11;272(10):686. DOI:10.1007/s00415-025-13420-6 2025
Mayte Sanchez van Kammen,Sanjit Aaron,Jorge M Ferreira et al.
Mayte Sanchez van Kammen et al.
Introduction: The incidence and outcomes of seizures among patients with severe cerebral venous thrombosis treated with decompressive surgery are unknown as are potential predictors of seizures in these patients. ...
Multicenter Study
Journal of neurology. 2025 Oct 10;272(10):685. DOI:10.1007/s00415-025-13410-8 2025
Feasibility, safety and efficacy of multi-dose vagus nerve stimulation in Parkinson's disease: a double-blind, randomised sham-controlled proof-of-concept study [0.03%]
多剂量迷走神经刺激治疗帕金森病的可行性、安全性和疗效:一项双盲随机对照假手术的概念验证研究
Hilmar P Sigurdsson,Heather Hunter,Lisa Alcock et al.
Hilmar P Sigurdsson et al.
Background: Gait and cognitive impairments are hallmark features of Parkinson's disease (PD) that significantly impact quality of life. These deficits arise from both dopaminergic and non-dopaminergic mechanisms, includin...
Randomized Controlled Trial
Journal of neurology. 2025 Oct 9;272(10):684. DOI:10.1007/s00415-025-13430-4 2025
Clinical characteristics, cerebellar MR spectroscopy and response to 3,4-diaminopyridine in spinocerebellar ataxia 27B: the Sheffield Ataxia Centre experience [0.03%]
脊髓小脑性共济失调27B的临床特征、小脑磁共振波谱成像及二氨基吡啶的治疗反应:谢菲尔德共济失调中心的经验
Ikechukwu Chukwuocha,David Pellerin,Priya Shanmugarajah et al.
Ikechukwu Chukwuocha et al.
Background: The clinical and genetic heterogeneity of hereditary ataxias presents a significant diagnostic challenge, particularly in sporadic adult-onset cases. Spinocerebellar ataxia type 27B (SCA27B) is caused by an in...
Super- and absolute responders to anti-cgrp monoclonal antibodies in migraine: A one-year multicenter, prospective, observational study [0.03%]
针对偏头痛患者抗CGRP单克隆抗体超级反应者和绝对反应者的为期一年的多中心前瞻性观察研究
Piero Barbanti,Cinzia Aurilia,Giulia Fiorentini et al.
Piero Barbanti et al.
Aim: To assess the frequency of super-responders (≥ 75% reduction in migraine frequency) and absolute responders (100% reduction) to monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) after...
Observational Study
Journal of neurology. 2025 Oct 9;272(10):683. DOI:10.1007/s00415-025-13419-z 2025
Impact of device pass count and reperfusion levels in anterior circulation stroke: differential effects based on large-scale data from clinical practice [0.03%]
基于大规模临床实践数据的前循环卒中装置通过次数和再灌注水平的影响:不同效应基于大规模实际临床数据分型分析
Luca Meucci,Lukas Meyer,Gabriel Broocks et al.
Luca Meucci et al.
Background: The relationship between angiographic success, number of device passes and functional outcome is a topic of clinical interest in endovascular thrombectomy (EVT) for acute ischemic stroke (AIS). This study syst...
Multicenter Study
Journal of neurology. 2025 Oct 9;272(10):682. DOI:10.1007/s00415-025-13417-1 2025
Predictors of relapse and disability in NMOSD, MOGAD, and double-seronegative demyelinating syndromes: an international multicenter retrospective cohort study [0.03%]
抗水通道蛋白抗体状态对NMOSD、MOGAD和双阴性脱髓鞘综合征复发和残疾影响的预测因素:一项国际多中心回顾性队列研究
Abdulkadir Tunç,Emine Rabia Koc,Edgar Carnero Contentti et al.
Abdulkadir Tunç et al.
Background: This international multicenter retrospective cohort study investigated predictors of relapse, acute attack severity, and six-month disability in patients with AQP4-IgG-positive NMOSD, MOGAD, and double-seroneg...
Multicenter Study
Journal of neurology. 2025 Oct 7;272(10):680. DOI:10.1007/s00415-025-13425-1 2025