Performance of blind source separation in localizing seizure onset from routine scalp-EEG [0.03%]
基于头皮 EEG 的盲源分离癫痫定位性能分析
Jeanne Benoit,Samuel Medina Villalon,Stanislas Lagarde et al.
Jeanne Benoit et al.
Objective: Blind source separation (BSS), decomposing signals into mixed sources, remains underexplored in ictal source imaging. We evaluated its ability to extract ictal components localizing the seizure onset zone (SOZ)...
Switch from intravenous anti-CD20 therapy to subcutaneous ofatumumab in patients with relapsing MS: results from the OLIKOS study [0.03%]
复发性多发性硬化症患者从静脉抗CD20疗法切换到Ofatumumab皮下治疗：OLIKOS研究结果
Le H Hua,Brandon Brown,Elizabeth Camacho et al.
Le H Hua et al.
Background: Multiple sclerosis (MS) is a chronic condition, and as such, switching therapies is not uncommon. However, data on switching from intravenous (IV) to subcutaneous (SC) formulations of anti-CD20 therapies are l...
Clinical Trial
Journal of neurology. 2025 Oct 24;272(11):725. DOI:10.1007/s00415-025-13462-w 2025
Cognitive awareness in people with multiple sclerosis before and after neuropsychological assessment [0.03%]
多发性硬化患者认知功能障碍评估前后的自我意识变化
P T Waskowiak,B A de Jong,B M J Uitdehaag et al.
P T Waskowiak et al.
Background: The association between subjective and objective cognitive functioning in people with multiple sclerosis (PwMS) is weak, making it difficult for clinicians to determine if referral for neuropsychological asses...
Observational Study
Journal of neurology. 2025 Nov 5;272(11):748. DOI:10.1007/s00415-025-13486-2 2025
E Matas,L Bau,L Romero-Pinel et al.
E Matas et al.
Background: The concept of benign multiple sclerosis (MS) is a matter of debate. In most definitions, only the Expanded Disability Status Scale (EDSS) score and disease duration are considered, although other factors may ...
Perceptual response characterization in acute vestibular implant stimulation [0.03%]
急性前庭电刺激的感知反应特征分析
B Volpe,B L Vermorken,S C J Van Boxel et al.
B Volpe et al.
Objectives: The vestibular implant is a promising treatment option for patients with bilateral vestibulopathy. However, perceptual responses to acute electrical vestibular stimulation remain poorly understood. These perce...
B Noli,B Muqaku,M Gouda et al.
B Noli et al.
Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders with overlapping clinical features, making differential diagnosis challenging. The AQEE and GGEE peptides, derived from the proVGF neuroprotein, ha...
Andrea Morotti,Qi Li,Adnan I Qureshi et al.
Andrea Morotti et al.
Associations between gut microbiota and multiple system atrophy: a Mendelian randomization study [0.03%]
基于孟德尔随机化研究的大肠杆菌与多系统萎缩的关系
Duo Wang,Yuan-Yuan Zhao,Yue Huang
Duo Wang
Background: Multiple system atrophy (MSA) is a rare and progressive neurodegenerative disorder characterized by Parkinsonism, cerebellar dysfunction, and autonomic failure. Emerging evidence suggests that gut microbiota m...
Early experience on omaveloxolone in adult patients with Friedreich's ataxia: a real-world observational study [0.03%]
奥马维克斯治疗弗里德赖希共济失调成人患者的早期真实世界观察研究经验
Salvatore Maria Lima,Marta Caltagirone,Christian Messina et al.
Salvatore Maria Lima et al.
Introduction: Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative spinocerebellar ataxia caused by a homozygous GAA triplet repeat expansion in the frataxin (FXN) gene. FRDA is a multisystem disorder in...
Observational Study
Journal of neurology. 2025 Nov 1;272(11):742. DOI:10.1007/s00415-025-13487-1 2025
When slowness is not Parkinsonism: hypothyroid-induced ataxia and cognitive slowing reversed by hormone replacement [0.03%]
当运动迟缓不是帕金森病时：由甲状腺功能减退引起的共济失调和认知迟缓通过激素替代得到逆转
Kamalesh Tayade,Abhiram Bhave,Haresh Bharote et al.
Kamalesh Tayade et al.