Fatigue prediction needs time: comparing the diagnostic value of short vs. prolonged cognitive load [0.03%]
疲劳预测需要时间：短时 vs 长时认知负荷的诊断价值比较
Stefanie Linnhoff,Tino Zaehle
Stefanie Linnhoff
Cell replacement in the degenerating cerebellum: a historical essay of discovery [0.03%]
小脑变性中的细胞替代：一次历史性的发现回顾
Lazaros C Triarhou
Lazaros C Triarhou
The article revisits neurobiological experiments conducted over the past 50 years, aimed at deciphering questions of cerebellar development and plasticity, and the integration of primordial cerebellar tissue into host brains by means of int...
Development of anti-LGI1 autoimmune encephalitis outcome rating score using the Rasch analysis [0.03%]
使用Rasch分析开发LGI1自身免疫性脑炎预后评分标准
Xiaoyang Li,Pranjal Gupta,Naveen K Paramasivan et al.
Xiaoyang Li et al.
Background: Anti-LGI1 autoimmune encephalitis is an immunotherapy-responsive condition with growing interest in clinical trial development. However, the lack of reliable outcome measures is a major barrier. We aim to desi...
Transcranial pulse stimulation to treat multiple system atrophy: a case report [0.03%]
经颅脉冲刺激治疗多系统萎缩的一项病例报告
Johannes Stalter,Karsten Witt
Johannes Stalter
Plasma NfL and GFAP in the preclinical stages of neurodegenerative diseases: insights from the UK Biobank [0.03%]
英国生物银行的无临床症状期神经退行性疾病患者血浆中NfL和GFAP的水平变化规律分析
Jolanda Buonocore,Enrico Fratto,Fulvia Arcuri et al.
Jolanda Buonocore et al.
Background: Plasma neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) are promising blood-based biomarkers of neuroaxonal injury and astrocytic activation, relevant in neurodegeneration. We investi...
Big multiple sclerosis data network: novel modelling approaches for real-world data analysis [0.03%]
大数据模型在网络MS数据中的应用及真实世界数据分析的新思路
M Trojano,P Iaffaldano,M Copetti et al.
M Trojano et al.
Objective: The objective of this study is to present a report from the Big Multiple Sclerosis Data (BMSD) statistics workshop (Bari - Italy, June 2023) which focused on advanced statistical approaches for real-world data ...
Measuring the effect of rozanolixizumab using the Myasthenia Gravis Impairment Index: analyses from the randomized phase 3 MycarinG study [0.03%]
使用重症肌无力障碍指数测量rozanolixizumab的效果：来自MycarinG研究的随机III期试验分析
Carolina Barnett-Tapia,Elena Cortés Vicente,Robert M Pascuzzi et al.
Carolina Barnett-Tapia et al.
Background: Generalized myasthenia gravis (gMG) is an autoimmune disease characterized by fluctuating muscle weakness. The MG Impairment Index (MGII) incorporates patients' perspectives (22 items) and physician evaluation...
Clinical Trial
Journal of neurology. 2025 Nov 8;272(12):752. DOI:10.1007/s00415-025-13480-8 2025
Past, present, and future of genomic technologies in cerebellar ataxias [0.03%]
基因组技术在小脑共济失调中的过去、现在和未来
Marie Lucain,Yannis Duffourd,Marlene Malbos et al.
Marie Lucain et al.
Inherited cerebellar ataxias (ICA) are a group of rare, genetically and clinically heterogeneous neurodegenerative disorders, often caused by a broad spectrum of genetic variants, including single nucleotide variants, structural variations,...
Familial multiple sclerosis is associated with accelerated progression to secondary progressive phase: a retrospective single-center cohort study [0.03%]
家族性多发性硬化症与加速进展至继发进展期相关：一项回顾性的单中心队列研究
Serkan Ozakbaş,Said Alizada,Can Caliskan et al.
Serkan Ozakbaş et al.
Background: Familial multiple sclerosis (MS), defined by the occurrence of MS in one or more relatives, is thought to represent a genetically influenced subtype of the disease. ...
Sensory integration deficits in Parkinson's disease with freezing of gait: cortical network dynamics and paradoxical dopaminergic modulation [0.03%]
帕金森病伴原地冻结的感官整合缺陷：皮质网络动力学和矛盾多巴胺能调节
Sijie Chen,Qiaodan Pan,Qing Zhao et al.
Sijie Chen et al.
Background: Freezing of gait (FOG) in Parkinson's disease (PD) is a disabling motor symptom with unclear pathophysiology. Beyond known basal ganglia dysfunction and cognitive impairment, sensory integration deficits are i...