Harmonized magnetic resonance imaging protocols for multiple sclerosis: HARMONY-MS, a pilot project [0.03%]
磁共振成像在多发性硬化病中的和谐计划：HARMONY-MS试点项目
Andrea Surcinelli,Ilaria Massa,Nicola Gentili et al.
Andrea Surcinelli et al.
Introduction: Magnetic Resonance Imaging (MRI) is central to multiple sclerosis (MS) management, yet practice often diverges from guidelines. Large-scale evaluations of harmonized referral and acquisition protocols remain...
Observational Study
Journal of neurology. 2025 Dec 22;273(1):39. DOI:10.1007/s00415-025-13581-4 2025
Decreased level of consciousness in acute ischemic stroke: risk factors, territories, stroke mechanisms and outcome. A single-centre cohort study [0.03%]
急性缺血性卒中意识水平下降的影响因素、梗死部位、病因及预后：单中心队列研究
P Palazzo,D Strambo,S Pistocchi et al.
P Palazzo et al.
Background: A decreased level of consciousness (DLOC) at onset is infrequent in patients with acute ischemic stroke (AIS). We assessed stroke localization, patient and stroke characteristics, revascularization rates, and ...
Serum neurofilament light chain as a biomarker of disease control in multiple sclerosis: a real-world cross-sectional analysis of therapeutic regimens [0.03%]
血清神经丝轻链作为多发性硬化症疾病控制生物标志物的实证横断面分析：不同治疗方案的效果
Agni M Konitsioti,Finja Schweitzer,Wibke Johannis et al.
Agni M Konitsioti et al.
Background: Serum neurofilament light chain (sNfL) is an established biomarker of disease activity and progression in persons with multiple sclerosis (PwMS), with studies showing elevated sNfL levels during relapses and p...
Multicenter Study
Journal of neurology. 2025 Dec 19;273(1):34. DOI:10.1007/s00415-025-13573-4 2025
Peripheral nerve complications of weight loss associated with novel antihyperglycemic agents: a cohort study [0.03%]
与新型抗高血糖药物相关的体重减轻引起的周围神经并发症：一项队列研究
Cullen O&#x;Gorman
Cullen O&#x;Gorman
Introduction: Weight loss can cause or exacerbate peripheral nerve disorders, including peripheral neuropathy and entrapments. Novel antihyperglycaemic agents, including glucagon-like peptide-1 receptor (GLP1R) agonists a...
Brain atrophy in autoimmune encephalitis: epidemiology, pathophysiology, clinical manifestations, treatment, and prognosis-an update [0.03%]
自身免疫性脑炎的脑萎缩：流行病学、发病机制、临床表现、治疗及预后的最新研究进展
Chenyi Lu,Yaohua Lin,Muwei Wu et al.
Chenyi Lu et al.
Purpose: Autoimmune encephalitis (AE) refers to a group of rare autoimmune diseases affecting the central nervous system. New research shows that it can trigger neurodegenerative changes, especially brain atrophy. This at...
The diagnostic value of plasma Aβ42 and Aβ40 in Alzheimer's disease: current status, challenges, and impacting variables [0.03%]
血浆Aβ42和Aβ40诊断阿尔茨海默病的价值：现状、挑战及影响因素
Xiuzhi Duan,Fengyi Wang,Weiwei Liu et al.
Xiuzhi Duan et al.
Alzheimer's disease (AD) is a group of central nervous system degenerative diseases that affect cognitive function. During the diagnosis of AD, the levels of amyloid-β 42 (Aβ42) and amyloid-β 40 (Aβ40) in plasma, as well as their ratio ...
Diagnostic utility of biomarkers in progressive supranuclear palsy: toward a biotyping framework [0.03%]
进行性核上性麻痹生物标志物的诊断效用：迈向生物分型框架
Christine Ryan,Christian Camargo,Teddy Salan et al.
Christine Ryan et al.
Progressive supranuclear palsy (PSP) is a rare and debilitating four-repeat (4R) tauopathy, characterized by motor dysfunction, cognitive decline, and oculomotor abnormalities, yet it lacks reliable biomarkers for early diagnosis, disease s...
Functional cervical dystonia: diagnostic accuracy of distinct clinical features [0.03%]
功能性颈肌张力障碍：不同临床特征的诊断准确性
José Fidel Baizabal-Carvallo,Marlene Alonso-Juarez,Joseph Jankovic
José Fidel Baizabal-Carvallo
Background: Functional dystonia (FD) is one of the most common presentations among patients with functional movement disorders (FMDs). However, FD affecting neck muscles has not been well studied, even though cervical dys...
Plasma p-Tau217 and GFAP predict widespread cognitive decline in Alzheimer's disease [0.03%]
血浆p-Tau217和GFAP可预测阿尔茨海默病的认知广泛衰退
Núria Guillén,Diana Esteller,Jordi Sarto et al.
Núria Guillén et al.
Introduction: Progression in Alzheimer's disease (AD) involves three main interrelated biological axes-tau deposition, neurodegeneration, and neuroinflammation-that jointly drive cognitive decline. Although several cerebr...
Guillain-Barré syndrome associated with immune checkpoint inhibitors exposure: a pharmacovigilance study [0.03%]
免疫检查点抑制剂相关吉兰-巴雷综合征的药物警戒研究
Jean Cabon,Mathilde Ducloie,Basile Chretien et al.
Jean Cabon et al.
Background: Guillain-Barré syndrome (GBS) is a life-threatening condition that has been associated with exposure to immune checkpoint inhibitors (ICIs); however, available data remain limited. ...
Observational Study
Journal of neurology. 2025 Dec 16;273(1):27. DOI:10.1007/s00415-025-13507-0 2025