Effectiveness of Rituximab in rElapsiNg Multiple SclErosis previously treated with hiGhly-Active Disease modifying thErapies (RENEGADE study) [0.03%]
复发性多发性硬化症患者使用里妥昔单抗的疗效研究(RENEGADE研究)
Clara Grazia Chisari,Salvatore Lo Fermo,Alessia Di Sapio et al.
Clara Grazia Chisari et al.
Background: Highly effective disease-modifying therapies (HEDMTs) for relapsing multiple sclerosis (RMS) have changed the landscape of MS treatment. However, their discontinuation may potentially result in recrudescence o...
Observational Study
Journal of neurology. 2025 Dec 24;273(1):47. DOI:10.1007/s00415-025-13520-3 2025
Effects of cerebrospinal fluid drainage on patients with aneurysmal subarachnoid hemorrhage: an updated systematic review and meta-analysis [0.03%]
脑脊液引流对动脉瘤性蛛网膜下腔出血患者的影响:系统回顾和meta分析的更新研究
Xinlong Chen,Peijun Zhao,Xingyuan Huang et al.
Xinlong Chen et al.
Objective: Cerebrospinal fluid drainage (CSFD) has been reported to be beneficial in patients with aneurysmal subarachnoid hemorrhage (aSAH), but there are controversial results among different studies. Moreover, the comp...
Vittorio Marchi (1851-1908) of Novellara, his method, and his discoveries in the striatum, the thalamus, and the cerebellum [0.03%]
维托里奥·马尔奇(1851-1908)与他对诺沃拉的贡献、方法及其在纹状体、丘脑和小脑的研究发现
Lazaros C Triarhou
Lazaros C Triarhou
In September 1885, the neuropathologists Vittorio Marchi and Giovanni Algeri presented at the 11th congress of the Italian Medical Association, held in Perugia, a new method for anterograde tracing of degenerating fibers after experimental ...
Psychiatric and behavioural side effects of antiseizure medications in epilepsy [0.03%]
癫痫患者抗惊厥药物的精神和行为不良反应
Stanley Lyndon,Barbara A Dworetzky,Gaston Baslet
Stanley Lyndon
Objective: To synthesise the contemporary evidence on psychiatric and behavioural side effects (PBSEs) of antiseizure medications (ASMs) in adults with epilepsy and provide actionable guidance for medication selection, mo...
Regional brain atrophy subtypes in spinocerebellar ataxia type 3: links to clinical performance and treatment response [0.03%]
第三型脊小脑萎缩的区域大脑萎缩亚型与临床表现和治疗反应之间的关系
Xinyuan Liu,Jing Guo,Xingang Wang et al.
Xinyuan Liu et al.
Spinocerebellar ataxia type 3 (SCA3) is characterized by strong phenotypic heterogeneity, underscoring the need to explore subtypes using objective structural neuroimaging approaches. Identifying neuroimaging heterogeneity in SCA3 could hel...
Lazaros C Triarhou
Lazaros C Triarhou
Earliest depiction of port wine stains, eye signs and ear deformity in the portrait of Edward Grimston (c. 1399-1478) by Petrus Christus [0.03%]
彼得鲁斯·克里斯图斯所绘爱德华·格里姆斯顿(约1399-1478年)画像中的酒渣鼻、眼征和耳畸形:最早的图像学证据
Hutan Ashrafian,Leanne Harling
Hutan Ashrafian
Massive cerebral venous air embolism without trauma or invasive procedure [0.03%]
无外伤或侵入性操作的脑静脉气栓症一例报告
Yu Shen,Meng-Ni Wu,Hsin-Miao Wang et al.
Yu Shen et al.
Fabiola Freri,Edoardo Gioele Spinelli,Elisa Canu et al.
Fabiola Freri et al.
Background: Structural MRI studies have shown hypothalamic atrophy and altered white matter (WM) connectivity in amyotrophic lateral sclerosis (ALS), as a possible substrate of hypermetabolism in this condition. However, ...
Serum and cerebrospinal fluid biomarkers as predictors of cognitive impairment in multiple sclerosis: a systematic review of longitudinal studies [0.03%]
系统综述:血清和脑脊液生物标志物可预测多发性硬化患者的认知损害
Giovanni Restuccia,Carla Susinna,Giulia Marafioti et al.
Giovanni Restuccia et al.
Background and aims: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system, characterized by inflammation, demyelination, gliosis, and neuronal loss. Cognitive disorders are part of the cli...