A patient with anti-IgLON5 disease associated with cerebral hemorrhage, multiple ischemic strokes, and kidney failure: case report [0.03%]
与脑出血、多发性缺血性卒中和肾功能衰竭相关的IgLON5自身免疫病患者：病例报告
Valeria Sajin,Moritz Philipp Böhringer,Jürgen Ebert et al.
Valeria Sajin et al.
Introduction: Anti-IgLON5 disease is a recently discovered, rare autoimmune disorder of the nervous system associated with autoantibodies against IgLON5. It manifests with sleep disorders, bulbar syndrome, gait instabilit...
Effect of late-onset on multiple sclerosis phenotype and outcome: evidence from a multi-national registry [0.03%]
来自国际多发性硬化登记处的延迟发病对多发性硬化表型和结果的影响：证据
Amira Souissi,Francesco Patti,Tim Spelman et al.
Amira Souissi et al.
Background: Multiple Sclerosis (MS) severity is influenced by several factors. Understanding the impact of age at disease onset may help to better characterize clinical and disease features across age groups. This study a...
Observational Study
Journal of neurology. 2026 Feb 4;273(2):114. DOI:10.1007/s00415-026-13632-4 2026
CSF1R mutations in an Italian population of early-onset dementia: a case series [0.03%]
意大利早发型痴呆患者中CSF1R基因突变的病例报告系列研究
Beatrice Pancaldi,Andrea Mastrangelo,Alessandro Zilioli et al.
Beatrice Pancaldi et al.
The diagnostic approach to subjects with early-onset dementia (EOD) is often challenging due to the broader range of possible etiologies as compared to late-onset dementia cases. Pathogenic variants in CSF1R gene have been increasingly repo...
NOACs effects in the secondary prevention of atrial fibrillation-related ischemic stroke/TIA: a systematic review and meta-analysis [0.03%]
非瓣膜性房颤患者预防卒中或TIA的口服抗凝药疗效的系统评价和meta分析
Jiali Zhao,Chunfu Chen,Lin Lu et al.
Jiali Zhao et al.
Aims: Rivaroxaban has been approved for the primary prevention of stroke with non-valvular atrial fibrillation caused by one or more risk factors. However, the optimal antithrombotic therapy for secondary prevention of st...
Meta-Analysis
Journal of neurology. 2026 Feb 3;273(2):113. DOI:10.1007/s00415-026-13635-1 2026
Substrates of 8.5-year clinical outcomes in aquaporin-4 IgG-positive neuromyelitis optica spectrum disorders [0.03%]
抗水通道蛋白-4免疫球蛋白阳性神经肌炎光谱障碍临床结局的决定因素
Monica Margoni,Mor Gueye,Alessandro Meani et al.
Monica Margoni et al.
Background: Only a few longitudinal studies, with follow-up duration up to 3.6 years, have assessed the substrates of relapses and disability in aquaporin-4 (AQP4) IgG-positive neuromyelitis optica spectrum disorders (NMO...
The interplay between GBA1 status and age of onset on cognitive, motor and non-motor outcomes in Parkinson's disease: multicenter cross-sectional study [0.03%]
GBA1状态与帕金森病患者认知、运动和非运动临床表现起病年龄之间的相互作用：多中心横断面研究
Claudia Ledda,Silvia Gallo,Micol Avenali et al.
Claudia Ledda et al.
Background and objectives: Age at onset is a key determinant of disease course in the general Parkinson's disease (PD) population, but its influence among GBA-PD remains undetermined. This study investigates whether age a...
Multicenter Study
Journal of neurology. 2026 Feb 1;273(2):111. DOI:10.1007/s00415-026-13639-x 2026
Association of mild cognitive impairment and obesity-metabolic status in middle-aged and elderly adults: a nationwide prospective cohort study [0.03%]
中老年人轻度认知障碍与肥胖代谢状况相关性全国前瞻性队列研究
Weijie Zhai,Anguo Zhao,Jun Zhang
Weijie Zhai
Objective: This study aimed to investigate the influence of different obesity-metabolic syndrome (MetS) statuses on mild cognitive impairment (MCI) and to explore the modifying roles of related factors. ...
Short-term memory conjunctive binding in subjective cognitive decline: A PET biomarker-based study [0.03%]
基于PET生物标志物的主观认知下降患者短期记忆连接整合能力研究
M A Cecchini,A Studart-Neto,N C Moraes et al.
M A Cecchini et al.
The Short-Term Memory Conjunctive Binding (STMCB) test assesses the ability to maintain integrated shape-colour associations in memory. It has been applied to detect Alzheimer's disease (AD) across the continuum, from preclinical stages and...
Real-world evaluation of an automated EEG spike detection software in a tertiary centre compared to a clinical reference standard [0.03%]
一项在三级医疗中心进行的评估：将一种自动脑电图棘波检测软件与临床参考标准进行比较的真实世界研究
C Cook,A Auwal,S Eglese et al.
C Cook et al.
Background: Interictal epileptiform discharges (IEDs) are transient spikes or waves that occur in electroencephalography (EEG) records and can help support the diagnosis and classification of epilepsy. High-throughput mac...
Comparative Study
Journal of neurology. 2026 Jan 30;273(2):108. DOI:10.1007/s00415-026-13636-0 2026
Prospective observational study of magnetic resonance imaging in anti-CD19 CAR T-cell-associated neurotoxicity [0.03%]
抗CD19 CAR-T细胞相关神经毒性的磁共振成像前瞻性观察研究
Gian Maria Asioli,Federica Pondrelli,Luca Spinardi et al.
Gian Maria Asioli et al.
Background: Immune effector cell-associated neurotoxicity syndrome (ICANS) is a frequent and potentially severe complication of anti-CD19 CAR T-cell therapy. Nevertheless, its neuroradiological characterization remains in...
Observational Study
Journal of neurology. 2026 Jan 30;273(2):109. DOI:10.1007/s00415-026-13638-y 2026