Correction to: GATA1 controls metadherin transcription to promote oxidative stress-induced podocyte injury [0.03%]
GATA1通过控制metadherin转录促进氧化应激诱导的足细胞损伤校正原文：GATA1控制metadherin转录以促进氧化应激引起的足细胞损伤
Yihua Chen,Wenting Wu,Liyuan Zhao et al.
Yihua Chen et al.
Yang Xiao,Yufang Ma,Can Gan et al.
Yang Xiao et al.
In metabolic dysfunction-associated steatotic liver disease (MASLD), lipid accumulation and inflammatory stimulation lead to the release of damage-associated molecular patterns, thereby inducing the activation of the cyclic GMP-AMP synthase...
Measuring Neural Factor X Pathway Activity in Rodent Glioma Cell Culture and Brain Slices [0.03%]
在啮齿动物胶质瘤细胞培养和脑切片中测量神经因子X通路活性
Valery Golderman,Shany Guly Gofrit,Maya Schiller et al.
Valery Golderman et al.
Coagulation factor X (FX) plays a significant role in neuroinflammation and is considered a promising target for therapeutic intervention. However, because activated FX (FXa) levels in neural tissues are expected to be significantly lower t...
Longitudinal analysis in Mecp2-het female mice reveals atypical nociceptive behaviours [0.03%]
纵向分析Mecp2杂合雌性小鼠的异常痛觉行为
Javier Cuitavi,Elena Martínez-Rodríguez,María Abellán-Álvaro et al.
Javier Cuitavi et al.
Rett Syndrome (RTT), a neurodevelopmental disorder predominantly affecting females, is characterised by evolving symptoms impacting motor and sensory domains. Herein, we present a study of longitudinal analyses, from 2- to 6-month of age, o...
The ApoA5-Cidec axis: keeping fibrosis and MASLD at bay [0.03%]
载脂蛋白A5-细胞分化调节因子CIDEc轴：防治纤维化和慢性肾脏病的一项新策略
Rita Sharma,Alexia Tasoula,Vishva M Sharma
Rita Sharma
Exploring the pathogenesis of NAFLD: a study of the correlation of gut microbes and metabolites in humanized mouse gut microbiota [0.03%]
非酒精性脂肪肝的发病机制研究：人源化小鼠肠道菌群的肠道微生物及代谢物相关性研究
Yuanzhi Cheng,Yun Yang,Yaxi Guo et al.
Yuanzhi Cheng et al.
There is mounting scientific evidence indicating a robust association between gut microbiota and nonalcoholic fatty liver disease (NAFLD). Exposure to commensal microbiota in germ-free mice has a significant impact on the regulatory mechani...
2,8-Dihydroxyadenine disrupts epithelial integrity and alters kidney cell phenotype in vitro [0.03%]
2,8-二羟基腺嘌呤体外干扰上皮细胞完整性并改变肾细胞表型
Hildur Run Helgudottir,Runolfur Palsson,Vidar Orn Edvardsson et al.
Hildur Run Helgudottir et al.
Adenine phosphoribosyltransferase (APRT) deficiency is an autosomal recessive disorder that causes accumulation of 2,8-dihydroxyadenine (DHA) in the urinary tract, leading to kidney stones and chronic kidney disease (CKD). Progression to en...
Spil-mediated sEH overexpression contributes to the senescence of alveolar epithelial cells during pulmonary fibrosis in mice [0.03%]
SP红霉素介导的sEH过表达促成了小鼠肺纤维化过程中肺泡上皮细胞衰老现象的发生
Chen-Yu Zhang,Wen-Jing Zhong,Jin-Tong Yang et al.
Chen-Yu Zhang et al.
Alveolar epithelial cell (AEC) senescence is a crucial driver of pulmonary fibrosis (PF). Epoxyeicosatrienoic acids (EETs) are synthesized from arachidonic acid through the cytochrome P450 cyclooxygenase (CYP) pathway. We have reported that...
The role of ferroptosis in renal cell carcinoma: molecular mechanisms and therapeutic implications [0.03%]
铁死亡在肾细胞癌中的作用：分子机制和治疗意义
Zhihong Wang,Depei Kong,Wuran Wei
Zhihong Wang
Of the numerous regulatory cell death mechanisms, ferroptosis has emerged as a pivotal player in the pathobiology of renal cell carcinoma (RCC), particularly the clear-cell subtype (ccRCC). This iron-dependent form of cell death, characteri...
Inverse correlation between plasma pyrophosphate hydrolysis and early growth of abdominal aortic aneurysm: a pilot study [0.03%]
血浆焦磷酸水解能力与腹主动脉瘤早期生长之间的负相关性：一项初步研究
Ricardo Villa-Bellosta,Jes S Lindholt,Jose Luis Martin-Ventura
Ricardo Villa-Bellosta
Abdominal aortic aneurysm (AAA) is often associated with vascular calcification, the calcium-phosphate crystal deposition in the aortic wall, which could impact aneurysm progression and/or stability. Tissue-nonspecific alkaline phosphatase ...