Evolution of conserved non-coding sequences within the vertebrate Hox clusters through the two-round whole genome duplications revealed by phylogenetic footprinting analysis [0.03%]
采用系统发育足迹分析研究两轮全基因组复制事件在脊椎动物HOX簇中保守非编码序列的进化
Masatoshi Matsunami,Kenta Sumiyama,Naruya Saitou
Masatoshi Matsunami
As a result of two-round whole genome duplications, four or more paralogous Hox clusters exist in vertebrate genomes. The paralogous genes in the Hox clusters show similar expression patterns, implying shared regulatory mechanisms for expre...
Vadim V Goremykin,Svetlana V Nikiforova,Olaf R P Bininda-Emonds
Vadim V Goremykin
Noisy data, especially in combination with misalignment and model misspecification can have an adverse effect on phylogeny reconstruction; however, effective methods to identify such data are few. One particularly important class of noisy d...
A tandem duplication of manganese superoxide dismutase in Nosema bombycis and its evolutionary origins [0.03%]
家蚕微孢子虫中锰超氧化物歧化酶串联重复及其进化来源
Heng Xiang,Guoqing Pan,Charles R Vossbrinck et al.
Heng Xiang et al.
Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnS...
Intronic AT skew is a defendable proxy for germline transcription but does not predict crossing-over or protein evolution rates in Drosophila melanogaster [0.03%]
在果蝇中,内含子AT偏斜可作为配体转录的可靠标记,但不能预测重组或蛋白质进化速率
Claudia C Weber,Laurence D Hurst
Claudia C Weber
Recent evidence suggests that germline transcription may affect both protein evolutionary rates, possibly mediated by repair processes, and recombination rates, possibly mediated by chromatin and epigenetic modification. Here, we test these...
Lack of evidence for sign epistasis between beneficial mutations in an RNA bacteriophage [0.03%]
关于RNA菌病毒中有利突变之间的表型上位性缺乏证据
Andrea J Betancourt
Andrea J Betancourt
In previous work (Betancourt, Genetics 181:1535, 2009), I propagated three large laboratory populations of an RNA phage (MS2) as they adapted to a controlled laboratory environment. These populations were large enough so that evolution migh...
Comparative genomics of marine mussels (Mytilus spp.) gender associated mtDNA: rapidly evolving atp8 [0.03%]
海洋贻贝壳关联mtDNA性别组学的比较基因组学:atp8的迅速进化
Beata Smietanka,Artur Burzyński,Roman Wenne
Beata Smietanka
The unusual mode of mitochondrial DNA inheritance, with two separate: maternal (F) and paternal (M) lineages, gives unique opportunities to study the evolution of the mitochondrial genome. This system was first discovered in the marine muss...
Comparative Study
Journal of molecular evolution. 2010 Dec;71(5-6):385-400. DOI:10.1007/s00239-010-9393-4 2010
Revisiting the thermodynamic theory of optimal ATP stoichiometries by analysis of various ATP-producing metabolic pathways [0.03%]
通过分析各种产ATP的代谢途径重新审视ATP的最佳化学计量比的热力学理论
Sarah Werner,Gabriele Diekert,Stefan Schuster
Sarah Werner
The stoichiometry of ATP-producing metabolic pathways had been analysed theoretically by several authors by using evolutionary arguments and optimality principles. Waddell et al. (Biochem Educ 27:12-13, 1999) analysed (lactate-producing) gl...
Genetic and evolutionary correlates of fine-scale recombination rate variation in Drosophila persimilis [0.03%]
模式生物果蝇persimilis种细尺度重组率变异的遗传及进化相关性研究
Laurie S Stevison,Mohamed A F Noor
Laurie S Stevison
Recombination is fundamental to meiosis in many species and generates variation on which natural selection can act, yet fine-scale linkage maps are cumbersome to construct. We generated a fine-scale map of recombination rates across two maj...
Evolution of dopamine-related systems: biosynthesis, degradation and receptors [0.03%]
多巴胺相关系统的进化:生物合成、降解和受体
Xianghui Ma,Zhiwen Wang,Xinbo Zhang
Xianghui Ma
The evolution of enzyme genes at the pathway level has attracted increasing attention in recent years. Most investigations have focused on microorganisms, plants and invertebrates but rarely on vertebrates. The dopamine pathway, which parti...
Loss of Octarepeats in two processed prion pseudogenes in the red squirrel, Sciurus vulgaris [0.03%]
红松鼠(Sciurus vulgaris)中两个加工的prion假基因的八聚体重复序列丢失
Ole Madsen,Timothy T Kortum,Marlinda Hupkes et al.
Ole Madsen et al.
The N-terminal region of the mammalian prion protein (PrP) contains an 'octapeptide' repeat which is involved in copper binding. This eight- or nine-residue peptide is repeated four to seven times, depending on the species, and polymorphism...