Ephemeral association between gene CG5762 and hybrid male sterility in Drosophila sibling species [0.03%]
果蝇姊妹物种中基因CG5762与杂种雄性不育的短暂关联
Daina Ma,Pawel Michalak
Daina Ma
Interspecies divergence in regulatory pathways may result in hybrid male sterility (HMS) when dominance and epistatic interactions between alleles that are functional within one genome are disrupted in hybrid genomes. The identification of ...
Amphiphilic α-helical potential: a putative folding motif adding few constraints to protein evolution [0.03%]
两亲性α-螺旋位形势能：一种可能的折叠模体，对蛋白质进化增加少量约束条件
S Y Ryan Lee,William Parker
S Y Ryan Lee
Evidence from a number of studies indicates that protein folding is dictated not only by factors stabilizing the native state, but also by potentially independent factors that create folding pathways. How natural selection might cope simult...
Yi Zhou,Helmae Wubneh,Clayton Schwarz et al.
Yi Zhou et al.
In a process similar to exon splicing, ciliates use DNA splicing to produce a new somatic macronuclear genome from their germline micronuclear genome after sexual reproduction. This extra layer of DNA rearrangement permits novel mechanisms ...
Phylogenetic and preliminary phenotypic analysis of yeast PAQR receptors: potential antifungal targets [0.03%]
酵母PAQR受体的系统发育和初步表型分析：潜在的抗真菌靶点
Nancy Y Villa,Patricia Moussatche,Stephen G Chamberlin et al.
Nancy Y Villa et al.
Proteins belonging to the Progestin and AdipoQ Receptor (PAQR) superfamily of membrane bound receptors are ubiquitously found in fungi. Nearly, all fungi possess two evolutionarily distinct paralogs of PAQR protein, which we have called the...
Toni I Gossmann,Karl J Schmid
Toni I Gossmann
Gene duplications are one of the most important mechanisms for the origin of evolutionary novelties. Even though various models of the fate of duplicated genes have been established, current knowledge about the role of divergent selection a...
Prestin shows divergent evolution between constant frequency echolocating bats [0.03%]
恒频回声定位蝙蝠听觉基因发散演化
Bin Shen,Rafael Avila-Flores,Yang Liu et al.
Bin Shen et al.
The gene Prestin encodes a motor protein that is thought to confer the high-frequency sensitivity and selectivity that characterizes the mammalian auditory system. Recent research shows that the Prestin gene has undergone a burst of positiv...
Ryoiti Kiyama,Yuko Wada-Kiyama
Ryoiti Kiyama
We provide here evidence for a conserved regulatory element for transcription of the β-family globin genes based on a comparative study of 32 genes from 16 mammals. The element is characterized by the appearance of AA or TT dinucleotides i...
Reconstructing the fungal tree of life using phylogenomics and a preliminary investigation of the distribution of yeast prion-like proteins in the fungal kingdom [0.03%]
基于系统基因组学重建真菌生命之树并初步研究酵母prion样蛋白在真菌界中的分布规律
Edgar M Medina,Gary W Jones,David A Fitzpatrick
Edgar M Medina
We have used three independent phylogenomic approaches (concatenated alignments, single-, and multi-gene supertrees) to reconstruct the fungal tree of life (FTOL) using publicly available fungal genomes. This is the first time multi-gene fa...
Interspecific and intragenic differences in codon usage bias among vertebrate myosin heavy-chain genes [0.03%]
脊椎动物肌球蛋白重链基因的种间和种内密码子使用偏好差异
Mikio C Aoi,Bryan C Rourke
Mikio C Aoi
Synonymous codon usage bias is a broadly observed phenomenon in bacteria, plants, and invertebrates and may result from selection. However, the role of selective pressures in shaping codon bias is still controversial in vertebrates, particu...
Selection and constraint on regulatory elements in Drosophila simulans [0.03%]
果蝇Drosophila simulans调控元件的选择及限制
Tami Cruickshank,Phil Nista
Tami Cruickshank
We utilized available Drosophila simulans molecular population genomic data to characterize sequence polymorphism in noncoding regulatory regions and their corresponding transcribed target genes or interacting transcription factors. We high...