Conservation of NLRP3 Inflammasome Pathway in Monotremes and Large-Scale Restructuring of the Caspase-1 Gene Cluster Region in Mammals [0.03%]
单孔目中NLRP3炎性小体通路的保守性和哺乳动物中Caspase-1基因簇区域的大规模重排
David Stevens,Tasman Daish,Frank Grützner
David Stevens
Activation of the NLRP3 inflammasome can be triggered by components of fungi, bacteria and viruses, as well as cellular stress and environmental irritants. The NLRP3 inflammasome has been well characterised in mouse and humans but limited i...
The evolutionary path of widespread IR heteroplasmy of chloroplast genomes in the context of Rhodophyta phylogeny [0.03%]
从红藻谱系的角度看裂体藻基因组广泛存在红外杂合性及其进化路径
Yang Li,Xiaomei Huang,Yuanhao Li et al.
Yang Li et al.
Ujwal Dahal,Rupendra Shakya,Bhumandeep Kour et al.
Ujwal Dahal et al.
A Bayesian Framework for the Network Analysis of Transmission Dynamics in Infectious Disease [0.03%]
传染病传播动力学的网络分析的贝叶斯框架
Jianing Xu,Jihyun Kim,Pengsheng Ji et al.
Jianing Xu et al.
Understanding the transmission dynamics of infectious diseases is critical for effective public health intervention. Traditional models often rely on simplifying assumptions that overlook the complexity of real-world contact patterns. In th...
Genetic Exchanges Shape the Evolutionary Diversification Among Shigella phages [0.03%]
基因交流塑造志贺氏菌噬菌体的进化分化
Joyeeta Chatterjee,Pratanu Kayet,Manisha Ghosh et al.
Joyeeta Chatterjee et al.
Shigella is a genus of bacteria that is a prevalent cause of bacterial diarrhoea (i.e., shigellosis). Shigella bacteriophages are shaping bacterial fitness. Bacteriophages can carry genes that contribute to Shigella virulence and antibiotic...
Molecular Phylogeny of "Chemosensory Proteins" in Bacteria and Arthropods: CSP as an Extremely Ancient Gene [0.03%]
细菌和节肢动物的“化学感受蛋白”分子系统发育：“化学感受蛋白”是一种极为古老的基因
Jean-François Picimbon
Jean-François Picimbon
In this research paper, I provided a comprehensive overview of "Chemosensory Proteins" (CSPs), which have traditionally been thought to be involved in transporting odorant or tastant molecules to chemosensory receptors. However, CSPs are pe...
Comparative Analysis of AlphaFold2 Models and Intrinsic Disorder Illuminates Structural Divergence as a Symptom of Functional Divergence Across the Calmodulin Superfamily [0.03%]
AlphaFold2模型的比较分析及其内在无序性表明结构分歧是钙调蛋白超家族功能分歧的症状
Kyoko Nakamura,Jessica Siltberg-Liberles
Kyoko Nakamura
Protein structure enables function. Eukaryotic genomes contain paralogous genes often encoding functionally diverse proteins forming superfamilies. As protein sequences evolve, their function may change but identifying functional divergence...
Type II LDH/MDH Oxidoreductases in Pacific Oyster Magallana gigas (Thunberg, 1793): Gene Organization and Expression Patterns During Development and Across Tissues [0.03%]
太平洋牡蛎马氏幼虫（Magallana gigas）中II型LDH / MDH氧化还原酶：发育过程中的基因组织与表达模式及各类组织的表达模式研究
Mikhail V Puzakov,Ludmila V Puzakova,Polina M Puzakova et al.
Mikhail V Puzakov et al.
Decoding the Evolution and Co-Phospho-Regulatory Networks of SHROOM Proteins [0.03%]
SHROOM蛋白的磷酸化调控网络及其进化分析
Noreen A Khan,Athira C Rajeev,Althaf Mahin et al.
Noreen A Khan et al.
2025 Zuckerkandl Prize [0.03%]
2025 扎克坎德尔奖
Megan G Behringer,Michael DeGiorgio,Maeva Perez et al.
Megan G Behringer et al.