Bioinformatic Study of Possible Acute Regulation of Acid Secretion in the Stomach [0.03%]
胃酸分泌急性调节的生物信息学研究
Yan Hay Grace Lee,Nicole T Cerf,Nicholas Shalaby et al.
Yan Hay Grace Lee et al.
The gastric H+,K+-ATPase is an integral membrane protein which derives energy from the hydrolysis of ATP to transport H+ ions from the parietal cells of the gastric mucosa into the stomach in exchange for K+ ions. It is responsible for the ...
Potential Role of Nrf2, HER2, and ALDH in Cancer Stem Cells: A Narrative Review [0.03%]
Nrf2、HER2 和 ALDH 在癌症干细胞中的潜在作用：叙事综述
Azadeh Fakhrioliaei,Sepideh Tanhaei,SeyedAbbas Pakmehr et al.
Azadeh Fakhrioliaei et al.
Cancer is one of the main causes of death among humans, second only to cardiovascular diseases. In recent years, numerous studies have been conducted on the pathophysiology of cancer, and it has been established that this disease is develop...
Study of the Membrane Activity of the Synthetic Peptide ∆M3 Against Extended-Spectrum β-lactamase Escherichia coli Isolates [0.03%]
合成肽∆M3对超广谱β内酰胺酶大肠杆菌膜活性的研究
Estefanía Fandiño-Devia,Gloria A Santa-González,Maria C Klaiss-Luna et al.
Estefanía Fandiño-Devia et al.
Escherichia coli is the most common microorganism causing nosocomial or community-acquired bacteremia, and extended-spectrum β-lactamase-producing Escherichia coli isolates are identified worldwide with increasing frequency. For this reaso...
Streamlined Biotinylation, Enrichment and Analysis for Enhanced Plasma Membrane Protein Identification Using TurboID and TurboID-Start Biotin Ligases [0.03%]
使用TurboID和TurboID-Start生物素连接酶对等离子膜蛋白进行增强识别的简化生物素标记、富集和分析方法
Mehmet Sarihan,Murat Kasap,Gurler Akpinar
Mehmet Sarihan
Plasma membrane proteins (PMPs) play pivotal roles in various cellular events and are crucial in disease pathogenesis, making their comprehensive characterization vital for biomedical research. However, the hydrophobic nature and low expres...
Schisandrin B Alleviates LPS Induced Mitochondrial Damage in C28I2 Cells [0.03%]
北沙参二醇B缓解LPS诱导的C28I2细胞线粒体损伤
Fei Hu,WenJie Hu,Hongming Xu
Fei Hu
Osteoarthritis is a common joint disease characterized by damage to the joint cartilage that occurs throughout the entire joint tissue. This damage primarily manifests as pain in the affected area. In clinical practice, medication is common...
Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals [0.03%]
不同哺乳动物孤立的心脏ryanodine受体的功能存在差异
Catherine Carvajal,Jiajie Yan,Alma Nani et al.
Catherine Carvajal et al.
Concerted robust opening of cardiac ryanodine receptors' (RyR2) Ca2+ release 1oplasmic reticulum (SR) is fundamental for normal systolic cardiac function. During diastole, infrequent spontaneous RyR2 openings mediate the SR Ca2+ leak that n...
Correction: Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity [0.03%]
校正：水生氨基酸侧链在CFTR氯离子通道窄选择过滤器中对电导率和选择性的作用
Paul Linsdell
Paul Linsdell
Published Erratum
The Journal of membrane biology. 2024 Apr;257(1-2):143-149. DOI:10.1007/s00232-023-00304-x 2024
Effects of Chemical Fixatives on Kinetic Measurements of Biomolecular Interaction on Cell Membrane [0.03%]
化学固定剂对细胞膜上生物分子相互作用的动态测量的影响
Tianbao Dong,Shengyang Wan,Yanhui Wang et al.
Tianbao Dong et al.
Understanding the interaction between ligands and membrane proteins is important for drug design and optimization. Although investigation using live cells is desirable, it is not feasible in some circumstances and cell fixation is performed...
Lidocaine Inhibits Rat Prostate Cancer Cell Invasiveness and Voltage-Gated Sodium Channel Expression in Plasma Membrane [0.03%]
利多卡因抑制雄性大鼠前列腺癌细胞的侵略性以及质膜中电压门控钠通道的表达
Nahit Rizaner,Scott P Fraser,Ilknur Bugan Gul et al.
Nahit Rizaner et al.
There is increasing evidence, mostly from breast cancer, that use of local anaesthetics during surgery can inhibit disease recurrence by suppressing the motility of the cancer cells dependent on inherent voltage-gated sodium channels (VGSCs...
Identification of Prognostic and Immune Characteristics of Two Lung Adenocarcinoma Subtypes Based on TRPV Channel Family Genes [0.03%]
基于瞬时受体电位V家族基因的两种肺腺癌亚型预后和免疫特征的识别
Jianhua Jiang,Pengchao Zheng,Lei Li
Jianhua Jiang
Lung adenocarcinoma (LUAD) is one of the deadliest malignant tumors worldwide. Transient receptor potential vanilloid (TRPV) channels take pivotal parts in many cancers, but their impact on LUAD remains unexplored. In this study, LUAD sampl...