Celebrating 50 Years of Single-Channel Recording with the Patch Clamp [0.03%]
纪念膜片钳技术发明50周年：单通道记录的里程碑
Luigi Catacuzzeno,Fabio Franciolini
Luigi Catacuzzeno
Fifty years ago, Erwin Neher and Bert Sakmann published a Nature paper on their recording of discrete, step-like currents of a few picoamps passing through individual acetylcholine receptor channels of frog muscle fibers. This observation, ...
Bilayer-Dependent Recognition of Docosahexaenoic Acid by the Transmembrane Domain of FATP3 [0.03%]
脂肪酸转运蛋白FATP3的跨膜结构域对二十二碳六烯酸的识别依赖于双层环境
Yi Ding,Yonghua Wang,Wen Chen
Yi Ding
Fatty acid Transport Protein 3 (FATP3) is a single-pass transmembrane protein implicated in the uptake and intracellular transport of long-chain fatty acids, yet the molecular contribution of its transmembrane domain (TMD) remains poorly de...
Dario M Genovese,Facundo L Scarzello,Georgina M Domini et al.
Dario M Genovese et al.
Yeasts are able to tolerate different environmental conditions, including stress situations. Given their broad applications in the food industry, their ability to adapt to stressful conditions is an active area of research. Lipid compositio...
Design of a Multi-Epitope Vaccine using β-barrel Outer Membrane Proteins Identified in Chlamydia trachomatis [0.03%]
基于沙眼衣原体β-桶状外膜蛋白的多表位疫苗设计
Amisha Panda,Jahnvi Kapoor,B Hareramadas et al.
Amisha Panda et al.
Chlamydia trachomatis is an obligate intracellular Gram-negative pathogen that causes sexually transmitted infections (STIs) and trachoma. Current interventions are limited due to the widespread nature of asymptomatic infections, and the ab...
Prema Kumari Agarwala,Shobhna Kapoor
Prema Kumari Agarwala
Aggressive cancer cells such as pancreatic cells exhibit an enhanced metastatic phenotype that involves cell migration and invasion. Cellular membrane deformation is a key process implicit in cell movement. This implicates a link between al...
Molecular Insights into Interactions between Ofloxacin and Ionic Micelles [0.03%]
分子水平奥司他韦与离子型micelles相互作用研究
Saqib Rabbani,Areesha Maryam,Muhammad Sohail et al.
Saqib Rabbani et al.
The growing antimicrobial resistance presents a challenge in developing new potent drugs, but this effort is hindered by a lack of information regarding how these new drugs would behave in biomembranes. Surfactants are considered mimetic mo...
Correction to: Introduction to Special Issue on Role of Membranes in the Pore-Formation Mechanism of Pore-Forming Proteins and Toxins [0.03%]
对专题“膜在孔形成蛋白和毒素机制中的作用”的介绍的更正
Kausik Chattopadhyay
Kausik Chattopadhyay
Published Erratum
The Journal of membrane biology. 2025 Jul 11. DOI:10.1007/s00232-025-00356-1 2025
Stomatin and Stomatin-Like Proteins Can Regulate Transporter Proteins Activity and Has a Role in Cancer Metastasis [0.03%]
stomatin 和 stomatin-like 蛋白调节转运蛋白活性并参与癌症转移
Abira Dey,Debabani Ganguly
Abira Dey
Stomatin, encoded by STOM gene, is an integral membrane protein found in a wide variety of species. Although years have passed since the identification of stomatin, little has been known about the functional insights of stomatin among which...
Passage of the Channel-Forming Agent Nystatin Through Ergosterol-Containing Lipid Membranes [0.03%]
含麦角固醇的脂质膜上的通道形成剂奈斯替丁的透过性研究
Megi Tinev,Luka Kristanc,Gregor Gomišček et al.
Megi Tinev et al.
The passage of nystatin through the ergosterol-containing phospholipid bilayer was studied on monovesicular and multivesicular giant unilamellar vesicles (GUVs and MVVs). Phase-contrast optical microscopy was used to examine vesicles compos...
Mycobacterium tuberculosis TtfA is a Highly Stable Membrane-Anchored DNA-Binding Protein [0.03%]
稳定锚定于膜的DNA结合蛋白米氏体TtfA
Saksham Jain,Akanksha Gajanan Patil,Saniya Patil et al.
Saksham Jain et al.
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a deadly intracellular pathogen, with a persistent infectivity and high morbidity rate. Mtb has successfully evaded drugs and modern antibiotics, while also deve...