Influence of specific immunotherapy on the activity of human T lymphocyte Kv1.3 voltage-gated potassium channels in insect venom allergic patients [0.03%]
昆虫毒液过敏患者特异性免疫治疗对人T淋巴细胞Kv1.3电压门控钾通道活性的影响
Marita Nittner-Marszalska,Andrzej Teisseyre,Bożena Jaźwiec et al.
Marita Nittner-Marszalska et al.
Kv1.3 channels play an important role in T lymphocytes function. CD4(+) and CD4(+)CD25(+) T cells are two broad categories of T cells that are critically involved in the immunoresponse to allergens and that are also a major target for aller...
Na,K-ATPase activity in mouse muscle is regulated by AMPK and PGC-1α [0.03%]
AMPK和PGC-1α调控小鼠肌肉Na,K-ATP酶活性
Maria S Ingwersen,Michael Kristensen,Henriette Pilegaard et al.
Maria S Ingwersen et al.
Na,K-ATPase activity, which is crucial for skeletal muscle function, undergoes acute and long-term regulation in response to muscle activity. The aim of the present study was to test the hypothesis that AMP kinase (AMPK) and the transcripti...
Vasily V Kuvichkin
Vasily V Kuvichkin
The basic problem of nuclear pore assembly is the big perinuclear space that must be overcome for nuclear membrane fusion and pore creation. Our investigations of ternary complexes: DNA-PC liposomes-Mg²⁺, and modern conceptions of nuclear...
New insights into the translocation route of enrofloxacin and its metalloantibiotics [0.03%]
恩罗氟沙星及其金属衍生物的新转运机制研究进展
C Ribeiro,S C Lopes,P Gameiro
C Ribeiro
Probing drug/lipid interactions at the molecular level represents an important challenge in pharmaceutical research, drug discovery and membrane biophysics. Previous studies showed that enrofloxacin metalloantibiotic has potential as an ant...
The death of ouabain-treated renal epithelial C11-MDCK cells is not mediated by swelling-induced plasma membrane rupture [0.03%]
ouabain诱导的肾小管上皮细胞死亡非渗透性肿胀所致
Alexandra Platonova,Svetlana Koltsova,Georgy V Maksimov et al.
Alexandra Platonova et al.
This study examined the role of cell volume modulation in plasma membrane rupture and death documented in ouabain-treated renal epithelial cells. Long-term exposure to ouabain caused massive death of C11-MDCK (Madin-Darby canine kidney) epi...
Lipid rafts and cytoskeletal proteins in placental microvilli membranes from preeclamptic and IUGR pregnancies [0.03%]
子痫前期和宫内生长受限胎盘微绒毛膜脂筏及细胞骨架蛋白分布差异研究
Gloria Riquelme,Catalina Vallejos,Nicole de Gregorio et al.
Gloria Riquelme et al.
Intrauterine growth restriction (IUGR) and preeclampsia (PE) are leading causes of perinatal and maternal morbidity and mortality. Previously we reported the expression of lipid rafts in classical microvillous membrane (MVM) and light micro...
Improved technique for reconstituting incredibly high and soluble amounts of tetrameric K⁺ channel in natural membranes [0.03%]
一种在自然膜中重构四聚体K+通道的改进方法
Mobeen Raja,Elisabeth Vales
Mobeen Raja
The reconstitution of large amounts of integral proteins into lipid vesicles is largely prompted by the complexity of most biological membranes and protein stability. We optimized a particular system which maximized the incorporation effici...
Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems [0.03%]
磷脂酰胆碱-癸酸和磷脂酰胆碱-癸胺体系所形成的脂质膜的界面张力
Aneta D Petelska,Zbigniew A Figaszewski
Aneta D Petelska
Interfacial tension has been determined for phosphatidylcholine (PC)-decanoic acid (DA) and PC-decylamine (DE) membranes. PC (lecithin), DA and DE were used in the experiments; the interfacial tension values of the pure components are 1.62...
William F Heinz,Jeffrey L Werbin,Eaton Lattman et al.
William F Heinz et al.
The spatial relationships between molecules can be quantified in terms of information. In the case of membranes, the spatial organization of molecules in a bilayer is closely related to biophysically and biologically important properties. H...