Derivation and validation of a nomogram based on clinical characteristics to diagnose endometriosis associated ovarian cancer preoperatively [0.03%]
基于临床特征建立和验证可用于术前诊断卵巢子宫内膜异位症的列线图模型
Ting Xu,Xianglin Nie,Lin Zhang et al.
Ting Xu et al.
Purpose: The preoperative diagnosis of endometriosis associated ovarian cancer (EAOC) remains challenging for lack of effective diagnostic biomarker. We aimed to study clinical characteristics and develop a nomogram for d...
FSTL3 is associated with prognosis and immune cell infiltration in lung adenocarcinoma [0.03%]
FSTL3与肺腺癌的预后和免疫细胞浸润相关
Xiangzhi Meng,Xiaojian Zhao,Boxuan Zhou et al.
Xiangzhi Meng et al.
Purpose: FSTL3 expression is altered in various types of cancer. However, the role and mechanism of action of FSTL3 in lung adenocarcinoma development and tumor immunity are unknown. We investigated the association betwee...
Ultrasound-based deep learning radiomics nomogram for risk stratification of testicular masses: a two-center study [0.03%]
基于超声的深度学习放射组学列线图对睾丸肿块进行风险分层：两项中心研究
Fuxiang Fang,Yan Sun,Hualin Huang et al.
Fuxiang Fang et al.
Objective: To develop an ultrasound-driven clinical deep learning radiomics (CDLR) model for stratifying the risk of testicular masses, aiming to guide individualized treatment and minimize unnecessary procedures. ...
Efficacy of CDK4/6 inhibitors combined with endocrine therapy in HR+/HER2- breast cancer: an umbrella review [0.03%]
CDK4/6抑制剂联合内分泌治疗在HR+/HER2-乳腺癌中的疗效：一项伞式综述
Dongqing Pu,Debo Xu,Yue Wu et al.
Dongqing Pu et al.
Background: The use of Cyclin-Dependent kinase 4 and 6 (CDK4/6) inhibitors has profoundly changed the challenge of endocrine therapy (ET) resistance in hormone receptor-positive (HR+)/HER2-negative (HER2-) breast cancer. ...
Long-term survival of stage IV melanoma patients: evaluation on 640 melanoma patients entering stage IV between 2014 and 2017 [0.03%]
四期黑色素瘤患者长期生存分析：对2014至2017年进入四期的640例黑色素瘤患者的评估
Markus Reitmajer,Ulrike Leiter,Lena Nanz et al.
Markus Reitmajer et al.
Purpose: Since the introduction of immune checkpoint inhibitors (ICI) and targeted therapies (TT), survival rates of metastatic melanoma patients have increased significantly and complete remissions are no longer rarities...
Mitophagy plays a "double-edged sword" role in the radiosensitivity of cancer cells [0.03%]
线粒体自噬在癌细胞的放射敏感性中扮演着"双刃剑"的角色
Qian Wang,Chengxin Liu
Qian Wang
Mitochondria are organelles with double-membrane structure of inner and outer membrane, which provides main energy support for cell growth and metabolism. Reactive oxygen species (ROS) mainly comes from mitochondrial and can cause irreversi...
Vemurafenib combined with chemotherapy achieved sustained remission in pediatric LCH: a multi-center observational study [0.03%]
维美拉芬尼联合化疗在儿童LCH中实现了持续缓解：一项多中心观察研究
Jiaying Lei,Wenxia Wang,Danna Lin et al.
Jiaying Lei et al.
Background: Langerhans cell histiocytosis (LCH) is a myeloid neoplasia with potentially fatal consequences, and about 2/3 of cases involve the BRAFV600E kinase-activated mutation. Vemurafenib, a BRAF inhibitor, has demons...
An update of predictive biomarkers related to WEE1 inhibition in cancer therapy [0.03%]
癌症治疗中与WEE1抑制相关的预测性生物标志物的最新研究
Zizhuo Wang,Wenting Li,Fuxia Li et al.
Zizhuo Wang et al.
Purpose: WEE1 is a crucial kinase involved in the regulation of G2/M checkpoint within the cell cycle. This article aims to comprehensively review the existing knowledge on the implication of WEE1 as a therapeutic target ...
Incidence of second malignancies in patients with thymic carcinoma and thymic neuroendocrine tumor [0.03%]
胸腺癌和胸腺神经内分泌肿瘤患者第二恶性肿瘤的发生率
Guanghao Qiu,Fuqiang Wang,Yun Wang
Guanghao Qiu
Objectives: Thymic carcinoma and thymic neuroendocrine tumor (NET) are rare and are more likely to develop second malignancies. The purpose of this study was to explore the incidence and lifetime risk of second malignanci...
Value of high-speed videoendoscopy as an auxiliary tool in differentiation of benign and malignant unilateral vocal lesions [0.03%]
高速视频内镜在声带良恶性病变鉴别诊断中的辅助价值
Jakub Malinowski,Wioletta Pietruszewska,Magdalena Kowalczyk et al.
Jakub Malinowski et al.
Purpose: The study aimed to assess the relevance of objective vibratory parameters derived from high-speed videolaryngoscopy (HSV) as a supporting tool, to assist clinicians in establishing the initial diagnosis of benign...