Regression of high-grade squamous intraepithelial lesions in women aged 30 years or younger: a retrospective cohort study [0.03%]
一项回顾性队列研究：30岁或以下女性的高级别鳞状上皮内病变的消退情况
Oliver M Schleicher,Anna K Dietl,Annika S Behrens et al.
Oliver M Schleicher et al.
Purpose: To assess the rate and timing of spontaneous regression of high-grade cervical intraepithelial lesions (CIN2/HSIL and CIN3/HSIL) in young women and to identify associated factors. ...
Interpreting the apparent benefit of thoracic radiotherapy in metastatic NSCLC: patient selection and analytical issues remain important-a comment on Xue et al [0.03%]
对徐等人关于非小细胞肺癌转移性肿瘤的研究的评论——评价胸部放疗的表面益处：患者选择和分析问题仍然重要
Lili Qin,Shasha Wang,Haifeng Qin
Lili Qin
Thoracic radiotherapy (TRT) has been proposed as a potentially beneficial adjunct to first-line targeted therapy or chemoimmunotherapy in metastatic non-small cell lung cancer (NSCLC). This commentary discusses the retrospective study by Xu...
Real-world insights into bone marrow carcinomatosis in metastatic breast cancer: a retrospective analysis from two large university breast cancer centers [0.03%]
转移性乳腺癌骨髓癌栓的现实世界研究见解：来自两个大型大学乳腺癌中心的回顾性分析
Nikolas Tauber,Melissa Neubacher,Niklas Amann et al.
Nikolas Tauber et al.
Purpose: Bone marrow carcinomatosis (BMC) is a rare but clinically relevant manifestation of metastatic breast cancer (mBC), characterized by diffuse marrow infiltration and hematologic dysfunction. Evidence on epidemiolo...
The prognostic potential of an immunology score in patients treated with curative surgery for non-small cell lung cancer [0.03%]
非小细胞肺癌根治术后患者预后评分中免疫学指标的作用研究
Sara Witting Christensen Wen,Signe Timm,Morten Borg et al.
Sara Witting Christensen Wen et al.
Purpose: Curative surgery is the best treatment for patients with early-stage non-small cell lung cancer (NSCLC), but around 40% experience recurrence impacting survival. Does the individual immunological status affect th...
Impact of early vs. delayed metastasis-directed therapy on clinical outcomes in high Gleason score metastatic prostate cancer: long-term results of a landmark cohort study (PROMPT-G) [0.03%]
早期与延迟转移灶导向治疗对高格利森分级评分的转移性前列腺癌临床结局影响：前瞻性队列研究（PROMPT-G）长期结果报告
Huizhu Chen,Xueying Ren,Yun Bai et al.
Huizhu Chen et al.
Purpose/objective(s): For patients who have received standard systemic treatment during the metastatic hormone-sensitive prostate cancer (mHSPC) stage, the optimal timing of radiotherapy (RT) is still not clear. We compar...
The influence of urban versus rural residence and travel distance on net income, out-of-pocket payments and quality of life in German head and neck cancer survivors [0.03%]
德国头颈部癌症幸存者中城市与农村居住地及旅行距离对净收入、自付费用和生活质量的影响
Jonas Rast,Theresa Wald,Veit Zebralla et al.
Jonas Rast et al.
Purpose: German HNC survivors frequently experience substantial financial burden (FB). Geographic distance to cancer care centers (CCC) may increase FB negatively affecting QoL and outcome by creating barriers to diagnosi...
The human trophoblast cell-surface antigen 2 (TROP-2) expression on metastasized breast cancer [0.03%]
转移性乳腺癌中人滋养层细胞膜表面抗原2(TROP-2)的表达
M Weich,L Christl,M Kiesel et al.
M Weich et al.
Purpose: The antibody-drug conjugates (ADCs) sacituzumab govitecan (SG) and datopotamab deruxtecan target trophoblast cell surface antigen 2 (TROP-2) and have shown significant efficacy in HER2-negative metastatic breast ...
Effects of CDDO‑TFEA on non‑small cell lung cancer growth, apoptosis, and stemness via the MEK/ERK pathway [0.03%]
CDDO-TFEA通过MEK/ERK途径抑制非小细胞肺癌的生长、凋亡和干细胞特性的影响
Jui-Ying Lee,Chia-Li Chung,Tzu-Ting Tseng et al.
Jui-Ying Lee et al.
Purpose: Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, and therapeutic resistance limits durable responses. We investigated the antitumor activity of CDDO-TFEA, a synthetic triflu...
Timosaponin AIII-based liposomes loaded with Auranofin for the induction of ferroptosis in anaplastic thyroid carcinoma [0.03%]
载有秋水仙酰胺AIII的包载奥拉芬的脂质体诱导甲状腺癌铁死亡
Xinyi Deng,Lei Yang,Dihua Li et al.
Xinyi Deng et al.
Purpose: Anaplastic thyroid carcinoma (ATC) is an exceptionally aggressive malignancy that, despite accounting for only 1%-1.5% of all thyroid cancers, is responsible for over half of thyroid cancer-related deaths. Charac...
Comment on: "The status and determinants of demoralization in patients with colorectal cancer: a cross-sectional study in China" [0.03%]
对“中国结直肠癌患者绝望感及其影响因素的横断面研究”的点评
Kunyu Han,Jiahe Wang,Jiumao Lin
Kunyu Han
Zhou et al. investigated demoralization syndrome (DS) among Chinese patients with colorectal cancer and identified cancer metastasis, anxiety, and depression as factors independently associated with greater DS severity. Their study provides...