Impact of comorbidities on treatment management and prognosis in patients with anaplastic thyroid cancer (ATC) [0.03%]
合并症对广泛型甲状腺癌(ATC)治疗管理和预后的影响
Teresa Augustin,Dmytro Oliinyk,Marlen Haderlein et al.
Teresa Augustin et al.
To evaluate the impact of comorbidities on treatment allocation and prognosis in anaplastic thyroid cancer, 137 patients from 10 German tertiary cancer centers treated with radiotherapy between 2001 and 2020 were analyzed. Four validated co...
Extracellular vesicles-derived non-coding RNA in leukemias and pre-leukemic syndromes: a systematic review [0.03%]
急性髓系白血病和癌前综合征中外泌体衍生非编码RNA的研究进展系统性综述
Narjes Seddighi,Malihe Najafpour,Mohammadreza Riyahi et al.
Narjes Seddighi et al.
Background: Hematological malignancies, including leukemia, lymphoma, and multiple myeloma, are among the most aggressive cancers, with high mortality rates and limited early diagnostic tools. Exosomes, nano-sized extrace...
Neoadjuvant SBRT and intraoperative electron radiotherapy in pancreatic cancer resection [0.03%]
新辅助立体定向体部放射治疗和术中电子束放疗在胰腺癌切除术中的应用
Gianella Cornejo,Alon Pikarsky,Ayala Hubert et al.
Gianella Cornejo et al.
Background/objectives: Pancreatic cancer surgery frequently results in positive margins and local recurrence despite multimodal treatment. This study evaluated whether combining neoadjuvant stereotactic body radiotherapy ...
Brahmi (Bacopa monnieri) plant preparation facilitates to enhance the activities of dendritic cells to control non-small cell lung cancer (NSCLC) [0.03%]
独脚金(Bacopa monnieri)促进树突状细胞抗非小细胞肺癌(NSCLC)作用的研究
R Ilaya Kumar,Kavya Jain,Prashasti Arora et al.
R Ilaya Kumar et al.
Background: Brahmi (Bacopa monnieri) plant preparation (BPP) has been recognizedfor its immunomodulatory capabilities, but its molecular and epigenetic effects onimmune cells in non-small cell lung cancer (NSCLC) remain u...
Performance of large language models in reporting oral health concerns and side effects in head and neck cancer: a comparative study [0.03%]
大型语言模型在头颈癌口腔健康问题和副作用报告中的表现：一项比较研究
Jonas Rast,Susanne Wiegand,Jana Biermann et al.
Jonas Rast et al.
Purpose: With increasing reliance on large language models (LLMs) for health information, this study evaluated reliability and quality, understandability, actionability, readability and misinformation risk of responses fr...
Safety and efficacy of zolbetuximab plus chemotherapy for claudin 18 isoform 2-positive advanced gastric cancer: initial report of real-world experience [0.03%]
扎莫特珠单抗联合化疗治疗CLDN18.2阳性晚期胃癌的安全性和有效性：真实世界初步经验报告
Keitaro Shimozaki,Akira Ooki,Shota Fukuoka et al.
Keitaro Shimozaki et al.
Purpose: This study evaluated the safety and preliminary efficacy of zolbetuximab plus chemotherapy in patients with claudin 18 isoform 2 (CLDN18.2)-positive advanced gastric cancer (AGC). ...
Unveiling hidden players: the role of intratumoral microbiota in gastrointestinal cancer dynamics [0.03%]
揭开隐形玩家的面纱：肿瘤内微生物群在胃肠癌症动态中的作用
Wanfen Tang,Fakai Li,Hongjuan Zheng et al.
Wanfen Tang et al.
The intratumoral microbiota has emerged as a critical modulator of gastrointestinal (GI) tumour pathogenesis, influencing cancer initiation, progression, and treatment response. Recent studies have revealed that tumour-resident microbes, su...
TC check: a web app for thyroid cancer recurrence prediction using explainable machine learning [0.03%]
基于可解释机器学习的甲状腺癌复发预测网络应用TC check
Huashu Wen,Xiaohua Li,Xia Zhao
Huashu Wen
Background: Thyroid cancer (TC) is one of the most prevalent endocrine malignancies, and its recurrence presents a major clinical challenge that can adversely affect patient prognosis and treatment outcomes. Despite the p...
Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin [0.03%]
基于空间组的综合分析鉴定出CD44是葛根素的作用靶点
Song-Yang Xi,Hui Zhang,Qi-Juan Wang et al.
Song-Yang Xi et al.
Background: Melanoma, a highly metastatic and treatment-resistant malignancy, urgently requires novel therapeutic strategies. Puerarin, a natural isoflavone with established anti-tumorigenic effects in diverse cancers, re...
Quality of care before and after initial certification at a German certified hereditary breast and ovarian cancer center [0.03%]
德国遗传性乳腺癌和卵巢癌中心认证前后护理质量的评估
Niklas Amann,Manuel Hörner,Henrik Spannring et al.
Niklas Amann et al.
Purpose: Genetic mutations contribute to around 10% of breast and 25% of ovarian cancers, with one third of patients having a familial cancer history. The German Consortium for Familial Breast and Ovarian Cancer was found...