The burden of nasopharyngeal carcinoma in countries of the Association of Southeast Asian Nations (ASEAN), 1990-2023: findings from the Global Burden of Disease Study 2023 [0.03%]
2023年全球疾病负担研究（GBD 2023）发现：1990年至2023年东南亚国家联盟（ASEAN）成员国鼻咽癌疾病负担分析
Lijun Cheng,Jianxin Dong,Jun Li
Lijun Cheng
Background: Nasopharyngeal carcinoma (NPC) remains a major cancer burden in parts of Asia, particularly in the Association of Southeast Asian Nations (ASEAN). However, the burden and trends within ASEAN have not been comp...
Correlation of preoperative radiological lymph node assessment with pathological nodal and tumor findings in tongue and oral floor squamous cell carcinoma [0.03%]
术前放射学淋巴结评估与舌和口底鳞癌病理淋巴结和肿瘤结果的相关性
Jannik Ketschau,Yannik Leonhardt,Cornelius Leopold et al.
Jannik Ketschau et al.
Purpose: Preoperative imaging is central to cervical lymph node staging in oral squamous cell carcinoma (OSCC). However, the pathological and biological determinants underlying radiological lymph node suspicion remain poo...
Ondansetron oral soluble pellicles vs. azasetron for preventing nausea and vomiting in patients receiving antitumor therapies: a comparative observational study [0.03%]
口服奥丹司琼包衣片与盐酸阿扎司琼预防抗肿瘤药物引起的恶心呕吐的疗效观察研究
Cheng Zhao,Haibao Cao,Shuowen Yan et al.
Cheng Zhao et al.
Objective: Ondansetron oral soluble pellicles (OSP) show satisfactory effects on preventing nausea and vomiting following antitumor therapies. This study aimed to compare the antiemetic efficacy and safety profiles of ond...
Hypoxia-induced endoplasmic reticulum stress mediates lenvatinib resistance in hepatocellular carcinoma through the IRE1α-XBP1s-HIF1α pathway [0.03%]
缺氧诱导的内质网应激通过IRE1α-XBP1s-HIF1α通路介导肝癌细胞对仑伐替尼耐药性
Chong Zhang,Yuxin Jiang,Jiatao Liu et al.
Chong Zhang et al.
Background: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths globally, with a dismal prognosis for advanced patients. Lenvatinib, a first-line anti-angiogenic agent, has improved clinical...
Health economic evaluation of Mirvetuximab soravtansine for the treatment of FRα-positive, platinum resistant ovarian cancer in Germany [0.03%]
德国抗FRα人单克隆抗体偶联药物Mirvetuximab Soravtansine治疗铂耐药卵巢癌的卫生经济学评价
Franz F Janke,Ross J Baldessarini,Dirk Bauerschlag et al.
Franz F Janke et al.
Purpose: Mirvetuximab soravtansine (MIRV) is an antibody-drug conjugate targeting the folate receptor α (FRα), approved for FRα-positive platinum-resistant ovarian cancer based on improved progression-free and overall ...
Malignant uterine PEComa: a narrative literature review and challenging case report [0.03%]
恶性子宫平滑肌瘤样PECOMA的文献综述及一例疑难病例报道
Mauro Francesco Pio Maiorano,Joana Sorino,Mario Della Mura et al.
Mauro Francesco Pio Maiorano et al.
Uterine perivascular epithelioid cell tumors (PEComas) are exceptional mesenchymal neoplasms of the gynecologic tract that often mimic common uterine lesions and lack pathognomonic clinical or radiologic features. We report a malignant uter...
Basal cell subsets, as biomarker to predict the therapeutic effect of neoadjuvant therapy for esophageal carcinoma [0.03%]
基底细胞亚群作为预测新辅助治疗食管癌疗效的生物标志物
Xiangbing Xin,Jiayu Lu,Xuxu Zhang et al.
Xiangbing Xin et al.
Background: At present, neoadjuvant therapy before surgery has important application prospects in esophageal carcinoma (ESCA). However, there is still a lack of effective biomarkers to predict the prognosis of neoadjuvant...
Evaluating reasoning models for therapy recommendations in gastrointestinal stromal tumors: expert and LLM-based evaluations of OpenAI o1 and DeepSeek-R1 [0.03%]
胃肠间质瘤治疗推荐推理模型的评估：OpenAI o1和DeepSeek-R1模型的专家与大语言模型基于的评价
Melissa Harbrücker,Franka Menge,Arshia Taebi et al.
Melissa Harbrücker et al.
Purpose: This study aims to evaluate two advanced reasoning LLMs in generating treatment recommendations for real-world gastrointestinal stromal tumor (GIST) cases and assess their concordance with multidisciplinary team ...
Self-reported awareness of the prevention and early detection of oral cancer: a survey of 50+ year old people in Germany [0.03%]
德国50岁以上人群口腔癌预防及早诊意识的自我报告调查
Lisa Felgendreff,Eva Baumann,Sarah Habig et al.
Lisa Felgendreff et al.
Purpose: Tumours of the oral cavity are an under-recognised type of cancer, with many people being diagnosed at a late tumour stage. This study investigated knowledge of signs, symptoms and risk factors of oral cancer in ...