Predictive value of Slug-positive circulating tumor cells for neoadjuvant chemotherapy response in mesenchymal malignancies [0.03%]
SLUG阳性循环肿瘤细胞预测肉瘤新辅助化疗疗效价值的研究
Niezhenghao He,Shilei Liu,Haowen Cui et al.
Niezhenghao He et al.
Purpose: To evaluate the predictive value of Slug-positive circulating tumor cells (CTCs) for responses to neoadjuvant chemotherapy in mesenchymal malignancies. ...
Photon counting computed tomography in head and neck squamous cell carcinoma: iodine concentration and histopathological features [0.03%]
光子计数CT在头颈鳞癌中的应用：碘浓度及病理特征分析
Alexey Surov,Raihanatou Diallo-Danebrock,Hagen Sonnemann et al.
Alexey Surov et al.
Purpose: Head and neck squamous cell carcinoma (HNSCC) is a common malignancy with increasing relevance in oncologic imaging. Photon-counting computed tomography (PCCT) allows for quantitative assessment in iodine concent...
Lactylation-augmented DCBLD1-mediated PDIA3 stabilization reprograms glycolysis metabolism in oesophageal cancer [0.03%]
乳酰化增强的DCBLD1介导的PDIA3稳定重组食道癌糖酵解代谢路径
Ming Yin,Shan Wang,HaiMin Liu et al.
Ming Yin et al.
Objective: Histone lactylation (Hla) represents a novel epigenetic mark priming cells toward the malignant state. Discoidin, CUB, and LCCL domain-containing type I (DCBLD1) has been reported as a carcinogenic gene so far....
Residential radon exposure and lung cancer histology and stage: a population-based ecological study in Central Germany [0.03%]
住宅氡暴露与肺癌的组织学和分期：德国中部地区的一项基于人口的生态学研究
Philipp Ernst,Tobias Rachow,Sebastian Henn et al.
Philipp Ernst et al.
Purpose: Residential radon exposure is recognised as one of the leading environmental risk factors for lung cancer and acts synergistically with tobacco smoking. Thuringia, Germany, exhibits high geogenic radon potential;...
Diagnostic performance and clinical limitations of sentinel lymph node biopsy in head and neck melanoma: a 20-year retrospective cohort study [0.03%]
头颈部黑色素瘤哨点淋巴结活检的诊断性能及临床局限性：一项20年的回顾性队列研究
Lukas Lükewille,Susanne Wiegand,Asita Fazel et al.
Lukas Lükewille et al.
Purpose: Sentinel lymph node biopsy (SLNB) is a standard procedure for nodal staging in cutaneous melanoma. However, its diagnostic performance in the head and neck region remains limited due to complex lymphatic drainage...
Diving into the transcriptional landscape of leukemic stem cells in acute myeloid leukemia at single-cell resolution [0.03%]
单细胞分辨率下探究急性髓系白血病中白血病干细胞的转录组景观
Zuzanna Rzetelska,Lidia Gil,Francesco Buccisano et al.
Zuzanna Rzetelska et al.
Purpose: The aim of this review is to summarize transcriptomic studies using single-cell RNA sequencing (scRNA-seq) and bulk RNA-seq to investigate leukemic stem cells (LSCs) population in acute myeloid leukemia (AML). ...
Prediction of personalized therapeutic response in pediatric clivus chordoma: chemoresistance test [0.03%]
儿科儿童斜坡部位未分化胆管索状瘤个性化治疗反应的预测：化学抗性试验
Sérgio Cavalheiro,Lorena Favaro Pavon,Caroline Brunetto de Farias et al.
Sérgio Cavalheiro et al.
Precision medicine has expanded therapeutic options for rare central nervous system tumors, yet actionable molecular targets remain limited in pediatric cases. Functional ex vivo drug-response assays may complement genomic approaches by ide...
Years of life lost in cutaneous squamous cell carcinoma: analysis of a prospective cohort of 1400 patients [0.03%]
1400例前瞻性队列中皮肤鳞状细胞癌的生命年损失分析
Klaus Dietz,Thomas K Eigentler,Helmut Breuninger
Klaus Dietz
Purpose: Cutaneous squamous cell carcinoma (cSCC) occurs predominantly in older adults. Disease-specific mortality is low, but conventional survival estimates do not capture the reduction in remaining life expectancy attr...
Molecular mechanisms of 5-FU resistance in colorectal cancer: the regulatory role of lncRNAs [0.03%]
长链非编码RNA对结直肠癌中氟尿嘧啶耐药的分子机制的影响作用研究
Bing Bai,Yaqiu Guo,Xiaojun Xie et al.
Bing Bai et al.
Long non-coding RNAs (lncRNAs) are non-coding RNAs (ncRNAs) that serve as key regulators of a variety of biological processes such as tumorigenesis and drug resistance. LncRNAs are more than 200 nucleotides in length and influence cancer pr...
Clinical significance of circulating FcγRIIa in the prognosis of patients with metastatic non-small cell lung cancer [0.03%]
循环FcγRIIa在转移性非小细胞肺癌患者预后中的临床意义
Xiaojie Wang,Yu Teng,Mei Jiang et al.
Xiaojie Wang et al.
Background: The tumor microenvironment plays a crucial role in determining the prognosis of tumors. Fc gamma receptor IIa (FcγRIIa), one of the three subtypes of FcγRII, is expressed on platelets and immunocytes such as...