Keith T Ballingall,Riccardo Tassi
Keith T Ballingall
The immunopolymorphism database (IPD) provides a single nomenclature for alleles at the major histocompatibility complex (MHC) loci for a range of different species. The minimum requirements for inclusion of a sheep class II DRB1 sequence i...
Genetic control of the B cell response to LPS: opposing effects in peritoneal versus splenic B cell populations [0.03%]
遗传控制的B细胞对LPS的反应：腹膜与脾脏B细胞群体的相反效应
A M Vale,E Hayashi,A Granato et al.
A M Vale et al.
Lipopolysaccharide (LPS) from gram-negative bacteria activates B cells, enabling them to proliferate and differentiate into plasma cells. This response is critically dependent on the expression of TLR4; but other genes, such as RP105 and MH...
Definition of Mafa-A and -B haplotypes in pedigreed cynomolgus macaques (Macaca fascicularis) [0.03%]
圈养猕猴（断眉(macaca fascicularis)）中Mafa-A和Mafa-B座位单体型的定义
Nel Otting,Gaby G M Doxiadis,Ronald E Bontrop
Nel Otting
The major histocompatibility complex (MHC) class I B gene/allelic repertoire was investigated in a pedigreed population of cynomolgus macaques of mixed Indonesian/Malaysian origin. The Mafa-B alleles detected in this cohort are mostly speci...
Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations [0.03%]
两种伊朗人群中杀伤细胞免疫球蛋白样受体(KIR)及其HLA-C配体的分布
Susan E Hiby,Maziar Ashrafian-Bonab,Lydia Farrell et al.
Susan E Hiby et al.
Killer cell immunoglobulin-like receptors (KIR) gene frequencies vary between populations and contribute to functional variation in immune responses to viruses,autoimmunity and reproductive success. This study describes the frequency distri...
Cattle Ly49 is polymorphic [0.03%]
牛Ly49是多态的
Melanie J Dobromylskyj,Timothy Connelley,John A Hammond et al.
Melanie J Dobromylskyj et al.
Cattle are the only non-primate species to have an expanded KIR gene family. In addition they have a single Ly49 gene, thought to be monomorphic. We have identified two additional Ly49 cDNA sequences in cattle that encode molecules predicte...
Genetic variants in the mannose receptor gene (MRC1) are associated with asthma in two independent populations [0.03%]
两个独立人群中甘露糖受体基因多态性与哮喘的关系研究
Takeshi Hattori,Satoshi Konno,Nobuyuki Hizawa et al.
Takeshi Hattori et al.
Mannose receptor is a member of the C-type lectin receptor family involved in pathogen molecular pattern recognition and thought to be critical in shaping host immune responses and maintaining homeostasis. The aim of this study was to inves...
Association of TNFAIP3 polymorphism with rheumatic heart disease in Chinese Han population [0.03%]
TNFAIP3基因多态性与中国汉族人群风湿性心脏病的关联分析
Rong Hua,Ji-bin Xu,Jiu-cun Wang et al.
Rong Hua et al.
In a pair-matched case-control study (239 versus 478) conducted in Chinese Han population, we investigated the association between tumor necrosis factor-alpha-induced protein 3 (TNFAIP3) gene, tumor necrosis factor receptor-associated facto...
KIR3DL1/S1 genotypes and KIR2DS4 allelic variants in the AB KIR genotypes are associated with Plasmodium-positive individuals in malaria infection [0.03%]
AB型KIR基因组中KIR3DL1/S1基因型和KIR2DS4等位基因变异与疟疾感染患者有关
Michiko Taniguchi,Masato Kawabata
Michiko Taniguchi
The importance of innate immunity in malaria has been suggested for early protection from maturation and multiplication of Plasmodium parasites injected via infected mosquitoes. In this study, the killer cell immunoglobulin-like receptor (K...
Identification and characterisation of a novel immune-type receptor (NITR) gene cluster in the European sea bass, Dicentrarchus labrax, reveals recurrent gene expansion and diversification by positive selection [0.03%]
欧洲海鲈免疫受体（NITR）基因家族的鉴定、定位和特征分析：正选择引发反复的基因扩张及多样化
Serena Ferraresso,Heiner Kuhl,Massimo Milan et al.
Serena Ferraresso et al.
In the last decade, a new gene family encoding non-rearranging receptors, called novel immune-type receptors (NITRs), has been discovered in teleost fish. NITRs belong to the immunoglobulin superfamily and represent an extraordinarily diver...
Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503 [0.03%]
HLA-B*3501和HLA-B*3503的装配及胞内转运
Vilasack Thammavongsa,Malinda Schaefer,Tracey Filzen et al.
Vilasack Thammavongsa et al.
Residue 116 of major histocompatibility complex (MHC) class I heavy chains is an important determinant of assembly, that can influence rates of ER-Golgi trafficking, binding to the transporter associated with antigen processing (TAP), tapas...