Investigating associations between HLA DQA1 ~ DQB1 haplotypes, H. pylori infection, metaplasia, and anti-CagA IgA seropositivity in a Turkish gastritis cohort [0.03%]
在一组土耳其胃炎患者中研究HLA-DQA1~DQB1单倍型、幽门螺旋杆菌感染、不典型增生和抗CagA-IgA阳性之间的关联
Mukaddes Colakogullari,Lokman Karatas,Zeynep Tatar
Mukaddes Colakogullari
Helicobacter pylori was reported as an important cause of gastritis, and gastric ulcers and CagA oncoprotein-producing H. pylori subgroups were blamed to increase the severity of gastritis. Disparities were reported in that the presence of ...
Immunogenetics, sylvatic plague and its vectors: insights from the pathogen reservoir Mastomys natalensis in Tanzania [0.03%]
免疫遗传学、丛林鼠疫及其传播媒介：来自坦桑尼亚病原体库的洞穴老鼠Mastomys natalensis的新见解
Lavinia Haikukutu,Japhet R Lyaku,Charles M Lyimo et al.
Lavinia Haikukutu et al.
Yersinia pestis is a historically important vector-borne pathogen causing plague in humans and other mammals. Contemporary zoonotic infections with Y. pestis still occur in sub-Saharan Africa, including Tanzania and Madagascar, but receive ...
Macroevolution of avian T cell receptor C segments using genomic data [0.03%]
利用基因组数据研究鸟类T细胞受体C区段的宏进化
Chunhong Liang,Lin Sun,Ying Zhu et al.
Chunhong Liang et al.
All jawed vertebrates have four T cell receptor (TCR) chains expressed by thymus-derived lymphocytes that play a significant role in animal immune defense. However, avian TCR studies have been limited to a few species, although their co-fun...
The KIR2DL1 intermediate upstream element participates in gene activation [0.03%]
KIR2DL1中间上游元件参与基因激活
Paul W Wright,Hongchuan Li,Md Ahasanur Rahman et al.
Paul W Wright et al.
The human KIR genes encode a family of class I MHC receptors that are expressed on subsets of NK cells. The expression of KIR proteins is controlled by a stochastic process, and competition between sense and antisense promoter elements has ...
Comparative genomics of the T cell receptor μ locus in marsupials and monotremes [0.03%]
有袋类和单孔类胎盘T细胞受体μ基因位点的比较基因组学研究
K A Morrissey,M R Stammnitz,E Murchison et al.
K A Morrissey et al.
T cells are a primary component of the vertebrate adaptive immune system. There are three mammalian T cell lineages based on their T cell receptors (TCR). The αβ T cells and γδ T cells are ancient and found broadly in vertebrates. The m...
Morgan E Janes,Allison Kinlein,Martin F Flajnik et al.
Morgan E Janes et al.
NKp30 is an activating natural killer cell receptor (NKR) with a single-exon variable (VJ)-type immunoglobulin superfamily (IgSF) domain. Such VJ-IgSF domains predate the emergence of the antigen receptors (immunoglobulin and T cell recepto...
Correlation between human leukocyte antigen ligands and killer cell immunoglobulin-like receptors in aplastic anemia patients from Shaanxi Han [0.03%]
汉族陕西籍再障患者HLA配体与杀伤细胞免疫球蛋白样受体相关性分析
Tianju Wang,Jun Qi,Manni Wang et al.
Tianju Wang et al.
Regulating natural killer (NK) cell responses in hematological malignancies largely depend on molecular interactions between killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen (HLA) class I ligands. The goal of the ...
Ancient fish lineages illuminate toll-like receptor diversification in early vertebrate evolution [0.03%]
古代鱼类谱系揭示了早期脊椎动物进化中 Toll 样受体的多样化发展
Kara B Carlson,Cameron Nguyen,Dustin J Wcisel et al.
Kara B Carlson et al.
Since its initial discovery over 50 years ago, understanding the evolution of the vertebrate RAG- mediated adaptive immune response has been a major area of research focus for comparative geneticists. However, how the evolutionary novelty o...
Increased circulating Th17 cell populations in patients with pancreatic ductal adenocarcinoma [0.03%]
胰腺导管腺癌患者循环中的Th17细胞群增加
Imteyaz Ahmad Khan,Nidhi Singh,Deepak Gunjan et al.
Imteyaz Ahmad Khan et al.
T-helper 17 (Th17) cells are a subset of CD4+ helper T cells that produce interleukin 17 (IL-17) and play a crucial role in the pathogenesis of inflammatory and autoimmune diseases. Few studies have been conducted to determine the role of T...
Ronald Bontrop,Martin Flajnik,Colm S O&#x;Huigin et al.
Ronald Bontrop et al.