Molecular evolution of the transcription factor PRDM genes and expression profiles in response to stimulations and spinal cord injury repair in lamprey (Lethenteron reissneri) [0.03%]
亚洲七鳃鳗转录因子PRDM基因的分子进化及其对刺激和脊髓损伤修复的响应模式分析
Jinyang Guo,Xinyu Du,Jiaqi Wu et al.
Jinyang Guo et al.
Positive regulatory domain member (PRDM) family proteins play important roles in nervous system development, neural stem cell proliferation and differentiation, and central nervous system inflammation. The unique evolutionary position of th...
Full-length gene polymorphism of the non-classical HLA-E in Estonian individuals [0.03%]
爱沙尼亚人HLA-E非全长基因多态性研究
Timo I Olieslagers,Ingrid Tagen,Mathijs Groeneweg et al.
Timo I Olieslagers et al.
Estonia is a small country in the Baltic region of Northern Europe with 1.3 million inhabitants. As a coastal area, the population of Estonia was subjected to migration influences. Due to this admixture of populations, HLA gene diversity in...
HLA diversity and signatures of selection in the Maniq, a nomadic hunter-gatherer population in Southern Thailand [0.03%]
泰国南部游牧狩猎采集人群Maniq的HLA多样性及选择印记
Helmut Schaschl,Tobias Herzog,Victoria Oberreiter et al.
Helmut Schaschl et al.
The Maniq, a small and isolated nomadic hunter-gatherer population from the rainforests of Southern Thailand, offer a unique context for investigating how demographic history, genetic drift, and pathogen-driven selection shape human leucocy...
Histocompatibility in Botryllus schlosseri and the origins of adaptive immunity [0.03%]
Botryllus schlosseri同种移植兼容性与适应性免疫的起源
Anthony W De Tomaso,Henry Rodriguez-Valbuena
Anthony W De Tomaso
The basal chordate, Botryllus schlosseri, undergoes a natural transplantation reaction that is controlled by a single, highly polymorphic locus called the fuhc. The fuhc is one of the most polymorphic loci ever described, with most populati...
Genome-wide diversity and MHC characterisation in a critically endangered freshwater turtle susceptible to disease [0.03%]
全基因组多样性和MHC表征：一种易受疾病影响的濒危淡水龟物种的研究
Holly V Nelson,Luke Silver,Toby G L Kovacs et al.
Holly V Nelson et al.
Small, isolated populations are often vulnerable to increased inbreeding and genetic drift, both of which elevate the risk of extinction. The Bellinger River turtle (Myuchelys georgesi) is a critically endangered species endemic to a single...
Correction to: HCV immunodominant peptide mapping reveals unique HLA‑A* 02‑restricted signatures: insights for CD8+ T‑cell‑based vaccines and immunotherapies [0.03%]
致：丙型肝炎病毒免疫显性肽图谱绘制揭示独特的HLA-A* 02限制特征：基于CD8+T细胞的疫苗和免疫治疗的启示校正发表信息
Laura Cardoso Corrêa-Dias,Ágata Lopes-Ribeiro,Geovane Marques-Ferreira et al.
Laura Cardoso Corrêa-Dias et al.
Published Erratum
Immunogenetics. 2025 Apr 23;77(1):20. DOI:10.1007/s00251-025-01377-9 2025
Allele co-segregation and haplotype diversity of MHC IIβ genes in the small-spotted catshark Scyliorhinus canicula [0.03%]
小斑猫鲨(MScyliorhinus canicula)MHC IIβ基因的等位基因共分离和单倍型多样性
Alessia Rota,Ana Veríssimo,Arnaud Gaigher
Alessia Rota
The major histocompatibility complex (MHC) constitutes a functionally relevant multigene family playing an essential role in the adaptive immune responses of jawed vertebrates, being directly involved in pathogen recognition. MHC diversity,...
Phylogenetic and structural insights into the origin of C-type lectin Mincle in vertebrates [0.03%]
脊椎动物C型凝集素Mincle起源的系统发育和结构研究
Taiki Ito,Carla Guenther,Eri Ishikawa et al.
Taiki Ito et al.
Our bodies are continuously exposed to injurious insults by infection and tissue damage, which are primarily sensed by innate immune receptors to maintain homeostasis. Among such receptors is macrophage-inducible C-type lectin (Mincle, gene...
Hans-Georg Rammensee,Olaf Rötzschke
Hans-Georg Rammensee
Suppressed activation of the IRF7 and TLR9 by JAK2V617F gold nanoparticles [0.03%]
JAK2V617F金纳米颗粒对IRF7和TLR9的激活抑制作用
Berkay Tokcan,Esra Nur Demirtaş,Selçuk Sözer
Berkay Tokcan
Philadelphia chromosome-negative myeloproliferative neoplasms (Ph-MPNs) are characterized by the overproduction of myeloid cells and a lack of response to cytokine signaling, along with genomic instability and the accumulation of nucleic ac...