MHC class I A loci polymorphism and diversity in three Southeast Asian populations of cynomolgus macaque [0.03%]
三种东南亚地区食蟹猴的I类主要组织相容性复合体A位点多态性及多样性研究
Yuki F Kita,Kazuyoshi Hosomichi,Sakae Kohara et al.
Yuki F Kita et al.
Cynomolgus macaques (Macaca fascicularis, Mafa) have emerged as important animal models for biomedical research, necessitating a more extensive characterization of their major histocompatibility complex polymorphic regions. The current info...
MHC class II polymorphism is associated with a canine SLE-related disease complex [0.03%]
主要组织相容性复合体II型多态性与犬系统性红斑狼疮相关疾病复杂性状有关
Maria Wilbe,Päivi Jokinen,Christina Hermanrud et al.
Maria Wilbe et al.
Nova Scotia duck tolling retrievers are predisposed to a SLE-related disease complex including immune-mediated rheumatic disease (IMRD) and steroid-responsive meningitis-arteritis (SRMA). IMRD involves symptoms that resemble those seen in s...
sTRAIL levels and TRAIL gene polymorphisms in Chinese patients with fatty liver disease [0.03%]
脂肪肝患者中TRAIL水平及其基因多态性研究
Xiaohua Yan,Liyun Xu,Jianni Qi et al.
Xiaohua Yan et al.
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily, and has been identified as a novel mediator of fatty liver disease (FLD). The aim of our study was to further investigate the relation...
On the genomics of immunoglobulins in the gray, short-tailed opossum Monodelphis domestica [0.03%]
灰短尾矮袋鼠单孔目动物免疫球蛋白的基因组学研究
Xinxin Wang,Jonathan J Olp,Robert D Miller
Xinxin Wang
Annotated maps of the IGH, IGK, and IGL loci in the gray, short-tailed opossum Monodelphis domestica were generated from analyses of the available whole genome sequence for this species. Analyses of their content and organization confirmed ...
Identification of natural killer cell receptor clusters in the platypus genome reveals an expansion of C-type lectin genes [0.03%]
鸭嘴兽基因组中的自然杀伤细胞受体群的鉴定揭示了C型凝集素基因的扩张
Emily S W Wong,Claire E Sanderson,Janine E Deakin et al.
Emily S W Wong et al.
Natural killer (NK) cell receptors belong to two unrelated, but functionally analogous gene families: the immunoglobulin superfamily, situated in the leukocyte receptor complex (LRC) and the C-type lectin superfamily, located in the natural...
Songlin Qiao,Yanyan Yang,Yunchao Liu et al.
Songlin Qiao et al.
Neutrophils and macrophages in cattle express a novel class of immunoglobulin Fc receptor, specific for bovine IgG2, termed boFcgamma2R. In cows, the ability of neutrophils to kill immunoglobulin-opsonized microorganisms appears to depend l...
Characterization of equine and other vertebrate TLR3, TLR7, and TLR8 genes [0.03%]
马及其他脊椎动物TLR3、TLR7和TLR8基因的鉴定
Natalia M Astakhova,Andrey A Perelygin,Andrey A Zharkikh et al.
Natalia M Astakhova et al.
Toll-like receptors 3, 7, and 8 (TLR3, TLR7, and TLR8) were studied in the genomes of the domestic horse and several other mammals. The messenger RNA sequences and exon/intron structures of these TLR genes were determined. An equine bacteri...
Comparative Study
Immunogenetics. 2009 Jul;61(7):529-39. DOI:10.1007/s00251-009-0381-z 2009
Maryam B Yassai,Yuri N Naumov,Elena N Naumova et al.
Maryam B Yassai et al.
T cell receptor (TCR) nucleotide sequences are often generated during analyses of T cell responses to pathogens or autoantigens. The most important region of the TCR is the third complementarity-determining region (CDR3) whose nucleotide se...
The bovine T cell receptor alpha/delta locus contains over 400 V genes and encodes V genes without CDR2 [0.03%]
牛T细胞受体alphadelta基因座包含400多个V基因，并且编码无CDR2的V基因
Peter Reinink,Ildiko Van Rhijn
Peter Reinink
Alphabeta T cells and gammadelta T cells perform nonoverlapping immune functions. In mammalian species with a high percentage of very diverse gammadelta T cells, like ruminants and pigs, it is often assumed that alphabeta T cells are less d...
Comparative Study
Immunogenetics. 2009 Jul;61(7):541-9. DOI:10.1007/s00251-009-0384-9 2009
Polymorphism and selection in the major histocompatibility complex DRA and DQA genes in the family Equidae [0.03%]
马达加斯加哺乳动物多样性形成的系统基因组学研究：灵长类动物、食肉动物和缨趾袋鼠科动物中的种群扩张与收缩事件
Eva Janova,Jan Matiasovic,Jiri Vahala et al.
Eva Janova et al.
The major histocompatibility complex genes coding for antigen binding and presenting molecules are the most polymorphic genes in the vertebrate genome. We studied the DRA and DQA gene polymorphism of the family Equidae. In addition to 11 pr...