Maryam B Yassai,Yuri N Naumov,Elena N Naumova et al.
Maryam B Yassai et al.
T cell receptor (TCR) nucleotide sequences are often generated during analyses of T cell responses to pathogens or autoantigens. The most important region of the TCR is the third complementarity-determining region (CDR3) whose nucleotide se...
The bovine T cell receptor alpha/delta locus contains over 400 V genes and encodes V genes without CDR2 [0.03%]
牛T细胞受体alphadelta基因座包含400多个V基因,并且编码无CDR2的V基因
Peter Reinink,Ildiko Van Rhijn
Peter Reinink
Alphabeta T cells and gammadelta T cells perform nonoverlapping immune functions. In mammalian species with a high percentage of very diverse gammadelta T cells, like ruminants and pigs, it is often assumed that alphabeta T cells are less d...
Comparative Study
Immunogenetics. 2009 Jul;61(7):541-9. DOI:10.1007/s00251-009-0384-9 2009
Polymorphism and selection in the major histocompatibility complex DRA and DQA genes in the family Equidae [0.03%]
马达加斯加哺乳动物多样性形成的系统基因组学研究:灵长类动物、食肉动物和缨趾袋鼠科动物中的种群扩张与收缩事件
Eva Janova,Jan Matiasovic,Jiri Vahala et al.
Eva Janova et al.
The major histocompatibility complex genes coding for antigen binding and presenting molecules are the most polymorphic genes in the vertebrate genome. We studied the DRA and DQA gene polymorphism of the family Equidae. In addition to 11 pr...
Elham Ashouri,Shirin Farjadian,Elaine F Reed et al.
Elham Ashouri et al.
Killer cell immunoglobulin-like receptors (KIR) regulate natural killer cell response against infection and malignancy. KIR genes are variable in the number and type, thereby discriminating individuals and populations. Herein, we analyzed t...
Evidence for balancing selection acting on KIR2DL4 genotypes in rhesus macaques of Indian origin [0.03%]
印度血统的食蟹猴中KIR2DL4基因型平衡选择作用的证据
Jeroen H Blokhuis,Marit K van der Wiel,Gaby G M Doxiadis et al.
Jeroen H Blokhuis et al.
The interaction of killer-cell immunoglobulin-like receptors (KIR) and their respective major histocompatibility complex (MHC) ligands can alter the activation state of the natural killer (NK) cell. In both humans and rhesus macaques, parti...
Comparative Study
Immunogenetics. 2009 Jul;61(7):503-12. DOI:10.1007/s00251-009-0379-6 2009
A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection [0.03%]
干扰素γ受体1启动子多态性与慢性乙型肝炎病毒感染易感性的关联研究
Jie Zhou,Ding-Qiang Chen,Vincent K M Poon et al.
Jie Zhou et al.
The antiviral cascade triggered by interferon-gamma (IFN-gamma) represents a vital event for eradicating hepatitis B virus (HBV) in experimental animals. IFN-gamma signaling is mediated through the ligand binding to IFN-gamma receptor 1 (IF...
Characterization of cynomolgus and vervet monkey placental MHC class I expression: diversity of the nonhuman primate AG locus [0.03%]
食蟹猴和绿猴胎盘MHC I类分子表达的特征:非人灵长类AG座位的多样性
Gennadiy I Bondarenko,Svetlana V Dambaeva,Richard L Grendell et al.
Gennadiy I Bondarenko et al.
Nonhuman primates are important animal models for the study of the maternal immune response to implantation within the decidua. The objective of this study was to define the placental expression of major histocompatibility complex (MHC) cla...
Extremely high MHC class I variation in a population of a long-distance migrant, the Scarlet Rosefinch (Carpodacus erythrinus) [0.03%]
长距离迁徙鸟类——红rise鸟(Carpodacus erythrinus)中极高的MHC I类基因多态性
M Promerová,T Albrecht,J Bryja
M Promerová
Although the number of studies focusing on the major histocompatibility complex (MHC) in non-model vertebrates is increasing, results are often contradictory, and the structure of MHC is still poorly understood in wild species. Here, we des...
Patterns of variation of the major histocompatibility complex class IIB loci in Chinese goose (Anser Cygnoides) [0.03%]
中国鹅主要组织相容性复合体IIb基因座变异类型的研究
Xu Zhou,Chunjin Li,Kangle Yi et al.
Xu Zhou et al.
In order to understand the variations of genomic organization of the major histocompatibility complex (MHC) and provide data for the studies on disease resistance of avian species, the MHC class II polymorphism in Chinese Z-goose was invest...
Origin and evolution of the vertebrate leukocyte receptors: the lesson from tunicates [0.03%]
脊椎动物白细胞受体的起源和进化:无颌类动物的启示
Ivana Zucchetti,Rosaria De Santis,Simona Grusea et al.
Ivana Zucchetti et al.
Two selected receptor genes of the immunoglobulin superfamily (IgSF), one CTX/JAM family member, and one poliovirus receptor-like nectin that have features of adhesion molecules can be expressed by Ciona hemocytes, the effectors of immunity...