Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS,S/AS01 vaccine [0.03%]
非洲人口遗传多样性对RTS,S/AS01疫苗免疫原性和效力的影响
Stephen Tukwasibwe,Gerald Mboowa,Ivan Sserwadda et al.
Stephen Tukwasibwe et al.
In modern medicine, vaccination is one of the most effective public health strategies to prevent infectious diseases. Indisputably, vaccines have saved millions of lives by reducing the burden of many serious infections such as polio, tuber...
Jeannine A Ott,Christian Mitchell,Morgan Sheppard et al.
Jeannine A Ott et al.
The genomes of most vertebrates contain many V, D, and J gene segments within their Ig loci to construct highly variable CDR3 sequences through combinatorial diversity. This nucleotide variability translates into an antibody population cont...
Characterization and genetic diversity of MHC class II DRB genes in the Arabian camel (Camelus dromedarius) [0.03%]
阿拉伯骆驼(MHC类II型DRB基因的特征及遗传多样性分析
Mohamed Habib Yahyaoui
Mohamed Habib Yahyaoui
This study investigated the MHC DRB genes in the Arabian camel (Camelus dromedarius). The results revealed the presence of - at least - two transcribed DRB-like genes in chromosome 20, designated MhcCadr-DRB1 and MhcCadr-DRB2. These genes a...
Tumor necrosis factor-α induces proliferation and reduces apoptosis of colorectal cancer cells through STAT3 activation [0.03%]
肿瘤坏死因子-α通过激活STAT3诱导结直肠癌细胞增殖并减少其凋亡
Wei Wei,Juanhong Wang,Pu Huang et al.
Wei Wei et al.
Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory factor that plays an important role in establishing a complicated connection between inflammation and cancer. TNF-α promotes tumor proliferation, migration, invasion, and an...
The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3' untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides [0.03%]
HLA-G 3′非翻译区+3010/C单核苷酸多态性（rs1710）与一个由92个核苷酸缺失的短转录本相关联
Erick C Castelli,Gabriela Sato Paes,Isabelle Mira da Silva et al.
Erick C Castelli et al.
The physiological expression of HLA-G is mainly observed in the placenta, playing an essential role in maternal-fetal tolerance. Among the HLA-G mRNA alternative transcripts, the one lacking 92 bases at the HLA-G 3' untranslated region (3'U...
Anshika Srivastava,Jill A Hollenbach
Anshika Srivastava
Published Erratum
Immunogenetics. 2023 Jun;75(3):321. DOI:10.1007/s00251-023-01300-0 2023
Expression analysis of Carassius auratus-leukocyte-immune-type receptors (CaLITRs) during goldfish kidney macrophage development and in activated kidney leukocyte cultures [0.03%]
金鱼肾巨噬细胞发育过程中及活化肾白细胞培养上金鱼Leukocyte-Immune Tyupe Receptors（CaLITR）表达分析
Jiahui Wang,Amro M Soliman,Jeff Norlin et al.
Jiahui Wang et al.
Carassius auratus leukocyte immune-type receptors (CaLITRs) were recently discovered immunoregulatory receptors in goldfish that have diverse immunoglobulin-like (Ig-like) ectodomains and intracellular signaling motifs. Genomic analysis sho...
Correction to: Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct [0.03%]
Correction to: 羊驼外周B细胞群体产生传统和重链型IgG亚型，在表型上无法区分但在免疫遗传学上却存在差异
Kevin A Henry,Henk van Faassen,Doreen Harcus et al.
Kevin A Henry et al.
Published Erratum
Immunogenetics. 2023 Apr;75(2):195. DOI:10.1007/s00251-023-01299-4 2023
Role of T cells in severe COVID-19 disease, protection, and long term immunity [0.03%]
T细胞在重症COVID-19发病机制、保护和长期免疫中的作用
Julia Maret Hermens,Can Kesmir
Julia Maret Hermens
Infection with SARS-CoV-2 causes wide range of disease severities from asymptomatic to life-threatening disease. Understanding the contribution of immunological traits in immunity against SARS-CoV-2 and in protection against severe COVID-19...
Marina Brand,Can Keşmir
Marina Brand
Vaccination clearly decreases coronavirus disease 2019 (COVID-19) mortality; however, they also impose selection pressure on the virus, which promotes the evolution of immune escape variants. For example, despite the high vaccination level ...