Strategies to prevent drug incompatibility during simultaneous multi-drug infusion in intensive care units: a literature review [0.03%]
重症监护病房中预防同时使用多种药物输注时发生药物不相容性的策略：综述文献
Laura Négrier,Anthony Martin Mena,Gilles Lebuffe et al.
Laura Négrier et al.
Purpose: Drug protocols in intensive care units may require the concomitant administration of many drugs as patients' venous accesses are often limited. A major challenge for clinicians is to limit the risk of simultaneou...
Evaluation of the effects of atazanavir-ritonavir on the pharmacokinetics of lumefantrine in patients living with HIV in Lagos University Teaching Hospital, South-Western Nigeria [0.03%]
尼日利亚拉各斯大学教学医院HIV患者中评估阿扎那韦-利托那韦对卢美latin1 Fanlatin1宁药代动力学影响的研究
Sikiru Olatunji Usman,Ibrahim Adekunle Oreagba,Michael Rotimi Kadri et al.
Sikiru Olatunji Usman et al.
Purpose: Atazanavir-ritonavir (ATVr)-based antiretroviral therapy and artemether-lumefantrine (AL) are commonly used drugs for the treatment of human immune deficiency virus (HIV) infection and malaria respectively. Howev...
S-warfarin limited sampling strategy with a population pharmacokinetic approach to estimate exposure and cytochrome P450 (CYP) 2C9 activity in healthy adults [0.03%]
基于人群药代动力学的S-华法林限采样策略在健康成人中的应用以估计暴露量和细胞色素P450（CYP）2C9活性
Lana Tran,Mina Nikanjam,Edmund V Capparelli et al.
Lana Tran et al.
Purpose: S-warfarin is used to phenotype cytochrome P450 (CYP) 2C9 activity. This study evaluated S-warfarin limited sampling strategy with a population pharmacokinetic (PK) approach to estimate CYP2C9 activity in healthy...
Sertraline concentrations in pregnant women are steady and the drug transfer to their infants is low [0.03%]
孕期妇女的盐酸舍曲林浓度稳定且该药物转移到其婴儿体内的量较低
E Heinonen,M Blennow,M Blomdahl-Wetterholm et al.
E Heinonen et al.
Purpose: Sertraline, a selective serotonin reuptake inhibitor (SSRI), is one of the most commonly used antidepressant during pregnancy. Plasma sertraline concentrations vary markedly between individuals, partly explained ...
Randomized Controlled Trial
European journal of clinical pharmacology. 2021 Sep;77(9):1323-1331. DOI:10.1007/s00228-021-03122-z 2021
Drug-drug interactions and inappropriate medicines impact on glycemic control and kidney function in older adults with diabetes-attending specialty care institution [0.03%]
药物相互作用及不适当用药对糖尿病专病机构就诊老年人血糖和肾功能的影响
Labib Al-Musawe,Carla Torre,Jose Pedro Guerreiro et al.
Labib Al-Musawe et al.
Purpose: To describe and assess the impact of polypharmacy, and its potential adverse reactions; serious clinically relevant drug-drug interactions (DDIs) and inappropriate medicines (PIMs) on glycemic target, and kidney ...
Luca Pasina,Barbara Rizzi,Alessandro Nobili et al.
Luca Pasina et al.
Background: Delirium is a neuropsychiatric syndrome associated with negative outcomes, including worsening of cognitive and functional status and an increased burden on patients and caregivers. Medications with anticholin...
Correction to: Iron chelation may harm patients with COVID-19 [0.03%]
Correction to：铁螯合可能对COVID-19患者造成伤害
Michael D Garrick,Andrew J Ghio
Michael D Garrick
Is there association between clinically relevant toxicities of pazopanib and sunitinib with the use of weak CYP3A4 and P-gp inhibitors? [0.03%]
帕唑帕尼和索拉非尼与临床相关的毒性与弱CYP3A4及P-糖蛋白抑制剂的使用有关吗？
Setayesh Sadeghi,Mona Kargar
Setayesh Sadeghi
Silvio Garattini
Silvio Garattini
There is a need of comparative studies to understand the differences in term of efficacy and safety of drugs with different mechanisms of action but similar therapeutic indications. This requires changes in the European Legislation of crite...
SGLT2 inhibitors and euglycemic diabetic ketoacidosis [0.03%]
sodium-glucose cotransporter 2抑制剂与正常血糖糖尿病酮症酸中毒
Zohaib Yousaf,Fateen Ata,Adeel Ahmad Khan et al.
Zohaib Yousaf et al.