Second-generation antipsychotic use during pregnancy and risk of congenital malformations [0.03%]
孕期间二代抗精神病药物的使用及其与先天畸形风险的关系
Maria Ellfolk,Maarit K Leinonen,Mika Gissler et al.
Maria Ellfolk et al.
Purpose: To study if second-generation antipsychotic (S-GA) use during the first trimester of pregnancy is associated with an increased risk of major congenital malformations (MCM). ...
Ana Mafalda Gonçalves Gonçalo,Maria Augusta Vieira-Coelho
Ana Mafalda Gonçalves Gonçalo
Trazodone is a widely used antidepressant that is also useful in the control of agitation and insomnia in Alzheimer's disease. This drug is now recognized as having a new mechanism of action, an effect on the unfolded protein response (UPR)...
Effect of a proton-pump inhibitor on intestinal microbiota in patients taking low-dose aspirin [0.03%]
质子泵抑制剂对小剂量阿司匹林服用者肠道微生物群的影响
Hiroyuki Tsujimoto,Yuki Hirata,Yasuhiro Ueda et al.
Hiroyuki Tsujimoto et al.
Background and aim: Low-dose aspirin (LDA) administration prevents cerebral infarction and myocardial infarction, but many studies found an association with mucosal injury. Proton-pump inhibitors (PPIs) can prevent gastri...
Randomized Controlled Trial
European journal of clinical pharmacology. 2021 Nov;77(11):1639-1648. DOI:10.1007/s00228-021-03167-0 2021
Marta Kučan,Igor Lulić,Jasenka Mršić Pelčić et al.
Marta Kučan et al.
Purpose: Arterial hypertension (AH) is associated with a high economic burden for the individual patient and for society in general. The study evaluates antihypertensives and their cost-effectiveness, comparing diuretics ...
Effects of pirenzepine on vonoprazan-induced gastric acid inhibition and hypergastrinemia [0.03%]
pirenzepine对vonoprazan所致胃酸抑制和高血 gastrin的作用
Takahiro Suzuki,Tomohiro Higuchi,Takuma Kagami et al.
Takahiro Suzuki et al.
Background: Compared to proton pump inhibitors, vonoprazan exerts a greater inhibitory effect on gastric acid secretion and is useful for treating acid-related diseases, such as gastro-esophageal reflux disease. However, ...
Randomized Controlled Trial
European journal of clinical pharmacology. 2021 Jul;77(7):971-978. DOI:10.1007/s00228-021-03162-5 2021
Severe rhabdomyolysis and acute kidney failure due to synthetic opioid brorphine exposure in combination with chronic sertraline therapy [0.03%]
合成阿片类药物溴普芬中毒合并长期舍曲林治疗导致严重横纹肌溶解和急性肾衰竭
Gasper Razinger,Damjan Grenc,Tomaž Pezdir et al.
Gasper Razinger et al.
Correction to: Estimation of a preliminary therapeutic reference range for children and adolescents with tic disorders treated with tiapride [0.03%]
Correction to: 估计用于治疗抽动障碍儿童和青少年的钛普利的初步治疗参考范围
Stefanie Fekete,K Egberts,T Preissler et al.
Stefanie Fekete et al.
Cardiovascular safety of long-term anti-obesity drugs in subjects with overweight or obesity: a systematic review and meta-analysis [0.03%]
长期抗肥胖药物的心血管安全性：针对超重和肥胖受试者的系统评价和meta分析
Lin Zhang,Zhi Liu,Shenling Liao et al.
Lin Zhang et al.
Purpose: Anti-obesity therapy can reduce body weight; however, it is not clear whether it can reduce major adverse cardiovascular events (MACEs). We conducted a systematic review and meta-analysis to assess the effect of ...
Correction to: Pharmacological evaluation of prophylactic anti-microbial use in laparoscopic cholecystectomy; an open labelled study evaluating the concentrations of single dose intravenous ceftriaxone at serum and tissue level [0.03%]
对胆囊切除术中预防性抗微生物药使用的药理评价的更正：一项开放标记研究，评估单剂量静脉注射ceftriaxone在血清和组织水平的浓度
Salim Sheikh,Neeraj Kumar Malik,Chakra Dhar Tripathi et al.
Salim Sheikh et al.
Predictors for a high apixaban level in elderly patients with atrial fibrillation prescribed reduced dose of apixaban [0.03%]
预测接受阿哌沙班减量治疗的老年人房颤患者高药物浓度的影响因素
Shinya Suzuki,Takeshi Yamashita,Masaharu Akao et al.
Shinya Suzuki et al.