Ability to detect potentially inappropriate prescribing in older patients: comparative analysis between PIM-Check and STOPP/STARTv2 [0.03%]
PIM-Check和STOPP/START V2规则识别潜在不适当用药的能力比较分析研究
Akram Farhat,Alice Panchaud,Amal Al-Hajje et al.
Akram Farhat et al.
Purpose: Potentially inappropriate prescribing (PIP) is a source of preventable adverse drug events. The objective of this study was a comparative analysis (quantitative and qualitative) between two tools used to detect P...
Observational Study
European journal of clinical pharmacology. 2021 Nov;77(11):1747-1756. DOI:10.1007/s00228-021-03171-4 2021
Shih-Wei Lai,Yu-Hung Kuo,Kuan-Fu Liao
Shih-Wei Lai
Markus Zeitlinger
Markus Zeitlinger
Research on Beers Criteria and STOPP/START Criteria based on the FDA FAERS database [0.03%]
基于美国食品药品监督管理局不良事件报告系统数据库的Beer's标准和STOPP/START标准研究
Qianqian Shao,Yulong Xu,Meng Li et al.
Qianqian Shao et al.
Purpose: Inappropriate medication criteria for the elderly have played an important role in ensuring the safety of medications for the elderly. Too few drugs included in the criteria cannot guarantee the safety of medicat...
The effects of polymorphisms in CYP2C19, ATP-binding cassette transporter B1, and paraoxonase-1 on clopidogrel treatment of Uygur patients following percutaneous coronary intervention [0.03%]
CYP2C19、ABCB1和PARAOXONASE-1多态性对维吾尔族患者经皮冠状动脉介入术后氯吡格雷治疗效果的影响研究
Tingting Wang,Hongjian Li,Fengxia Wang et al.
Tingting Wang et al.
Background: Acute coronary syndrome (ACS) carries a high mortality in Uygur populations. Percutaneous coronary intervention (PCI) is a safe treatment for patients with ACS. Clopidogrel reduces the risk for recurrent cardi...
Observational Study
European journal of clinical pharmacology. 2021 Nov;77(11):1679-1686. DOI:10.1007/s00228-021-03176-z 2021
Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens [0.03%]
用于优化剂量的静脉和口服环丙沙星在儿童中的群体药代动力学研究
D Hirt,M Oualha,B Pasquiers et al.
D Hirt et al.
Purpose: This study aimed to characterize pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing scheme. Methods: ...
Lack of association between CYB5A gene rs1790834 polymorphism and the response to leflunomide in women with rheumatoid arthritis [0.03%]
CYB5A基因多态性与女性类风湿关节炎患者来氟米特疗效无相关性分析
Małgorzata Łączna,Damian Malinowski,Agnieszka Paradowska-Gorycka et al.
Małgorzata Łączna et al.
Aim: Leflunomide is a disease-modifying antirheumatic drug used in therapy for rheumatoid arthritis (RA). Previous studies indicated that oestrogens and androgens may affect the response to leflunomide in RA patients. The...
A patient-centred web-based adverse drug reaction reporting system identifies not yet labelled potential safety issues [0.03%]
基于患者的网络不良事件报告系统可识别出尚未注明的潜在安全性问题
J Hasford,F Bruchmann,M Lutz et al.
J Hasford et al.
Purpose: Reporting of adverse drug reactions (ADRs) by patients is essential for a comprehensive risk-benefit evaluation of drugs after marketing, but only few data are available regarding patient-centred web-based ADR re...
Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial [0.03%]
褪黑素辅助治疗糖尿病疼痛性神经病变的临床疗效研究：一项随机、双盲、对照试验
Maryam Shokri,Firozeh Sajedi,Younes Mohammadi et al.
Maryam Shokri et al.
Purpose: The trial aimed to investigate the effectiveness of exogenous melatonin as an adjuvant to pregabalin for relief of pain in patients suffering from painful diabetic neuropathy (PDN). ...
Randomized Controlled Trial
European journal of clinical pharmacology. 2021 Nov;77(11):1649-1663. DOI:10.1007/s00228-021-03170-5 2021
REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors (REMEDI[e]S): French implicit and explicit criteria [0.03%]
老年人潜在不适当用药评估：隐性和显性标准（REMEDISES）法文版
Barbara Roux,Julie Berthou-Contreras,Jean-Baptiste Beuscart et al.
Barbara Roux et al.
Purpose: To establish a consensus on both explicit and implicit criteria in order to identify potentially inappropriate prescribing (PIP) in French older people aged 75 years and over or 65 years and over with multimorbid...