Safety and efficacy of intravenous tenecteplase in patients with acute ischemic stroke in the extended time window: an updated meta-analysis [0.03%]
替奈普酶静脉给药在大时间窗急性缺血性卒中患者中的安全性和有效性：一项更新的meta分析
Mokhtar Rejili,Yumna Khan,Anurag Rawat et al.
Mokhtar Rejili et al.
Background: We performed an updated systematic review and meta-analysis to evaluate tenecteplase 0.25 mg/kg in the extended time window. Methods: ...
"Ondansetron augmentation for obsessive-compulsive disorder: A systematic review and meta-analysis of randomized placebo-controlled trials" [0.03%]
奥丹司琼增效治疗强迫症：系统评价和meta分析
Anas Mohammad,Mohammad Ibrahim,Aneeq Mahmood Khan et al.
Anas Mohammad et al.
Background: A substantial proportion of adults with obsessive-compulsive disorder (OCD) experience persistent symptoms despite optimized first-line treatment with exposure and response prevention and/or serotonin reuptake...
Development and validation of high-dose methotrexate population pharmacokinetic models to inform clinical decisions on dosing [0.03%]
高剂量甲氨蝶呤群体药代动力学模型的建立与验证以指导临床给药决策
Marisa H Blackman,Bradley Yelvington,Cole Beck et al.
Marisa H Blackman et al.
Purpose: High-dose methotrexate is an effective treatment for adult and pediatric patients with acute lymphoblastic leukemia, osteosarcoma, and lymphoma. However, its clearance is highly variable, and delayed clearance ca...
Dysesthesia associated with GLP-1 agonist therapies: data-mining analysis and literature review [0.03%]
关于GLP-1受体激动剂治疗的异常感觉不良反应：数据分析与文献回顾
Marie-Laure Laroche,Hélène Géniaux,Manon Jardou
Marie-Laure Laroche
Purpose: An increasing number of anecdotal reports on social media platforms and medical blogs describe dysesthesia, particularly burning skin sensations, in association with glucagon-like peptide-1 receptor (GLP-1R) agon...
The influence of hydroxychloroquine on the risk of pre-eclampsia, hypertension, and premature delivery in patients with systemic lupus erythematosus during pregnancy: a meta-analysis [0.03%]
羟氯喹对系统性红斑狼疮患者妊娠期子痫前期、高血压和早产风险的影响：一项荟萃分析
Dong Liu,Yingying Chen,Fang Liu
Dong Liu
Objective: To evaluate the associations between hydroxychloroquine (HCQ) use and the risks of pre-eclampsia, hypertensive disorders of pregnancy (HDP), and preterm delivery in pregnant women with systemic lupus erythemato...
The Effect of the combination therapy of statin and dapagliflozin, a selective inhibitor of sodium_glucose Co-transporter type 2, in the treatment of Ischemic heart disease with heart failure: A randomized controlled trial [0.03%]
他汀类药物与钠葡萄糖共转运体2选择性抑制剂达格列净联合治疗缺血性心肌病合并心力衰竭的疗效：一项随机对照试验
Asmaa M Abdelkader,Hasnaa Osama,Eman S Hassan et al.
Asmaa M Abdelkader et al.
Purpose: Gliflozins (SGLT2 inhibitors) and statins are key treatments commonly used in patients with ischemic heart failure. Although both are well known for diminishing cardiovascular risk and heart failure-related morta...
Randomized Controlled Trial
European journal of clinical pharmacology. 2026 May 14;82(6):152. DOI:10.1007/s00228-026-04050-6 2026
Healthcare professionals' perspectives on medication adherence-supporting tools: a cross‑sectional survey in Italy [0.03%]
意大利医疗专业人员视角下的药物依从性支持工具调查
Monia Donati,Carlotta Lunghi,Giulia Grillini et al.
Monia Donati et al.
Purpose: Medication adherence is essential for treatment effectiveness, yet the uptake of adherence-supporting tools in routine care remains suboptimal. This study assessed Italian healthcare professionals' knowledge, per...
Comparison of loop diuretics for chronic heart failure: a systematic review and meta-analysis [0.03%]
利尿剂治疗慢性心力衰竭的疗效和安全性：系统评价和meta分析
Sami Taleghani,Cecilie C Sørensen,Jasmin Dam Lukoschewitz et al.
Sami Taleghani et al.
Background: Loop diuretics relieve congestion in chronic heart failure (CHF). We systematically reviewed randomised clinical trials (RCTs) evaluating their effects. ...
Short-term effect of rosuvastatin versus atorvastatin on the corrected QT interval: a target trial emulation [0.03%]
Rosuvastatin与阿托伐他汀对校正QT间期短期影响的靶向试验模拟研究
Xin Chen,Yang Liu,Wei Wei et al.
Xin Chen et al.
Objective: To estimate the short-term effect of rosuvastatin versus atorvastatin on the corrected QT interval (QTc) by emulating a published randomized controlled trial (RCT) using electronic health record (EHR) data, and...