Comparative efficacy and safety of carboplatin-based versus cisplatin-based chemotherapy in muscle-invasive and advanced bladder cancer: A systematic review and meta-analysis [0.03%]
卡铂与顺铂为基础的化疗治疗肌层浸润性及晚期膀胱癌疗效和安全性的比较：系统评价和Meta分析
Jiahao Liao,Xiaomeng Li,Guowei Li
Jiahao Liao
Background: Cisplatin-based chemotherapy is the standard of care for muscle-invasive and advanced bladder cancer, but its significant toxicity renders approximately 30-50% of patient ineligible. Carboplatin is widely used...
Efficacy of NEPA for prevention of chemotherapy induced nausea and vomiting in head and neck cancer patients receiving cisplatin-based chemotherapy [0.03%]
奈培洛芬预防头颈部肿瘤患者顺铂引起的化疗恶心呕吐疗效观察
Tzer-Zen Hwang,Chih-Chun Wang,Chuan-Chien Yang et al.
Tzer-Zen Hwang et al.
Background: A 5-hydroxytryptamine-3 receptor antagonist (5-HT3RA) in combination with a neurokinin-1 receptor antagonist (NK-1RA) are effective for the prevention of chemotherapy induced nausea and vomiting. ...
SGLT2 inhibitors and incretin-based therapies for metabolic dysfunction-associated steatohepatitis: a systematic review [0.03%]
用于代谢紊乱相关性非酒精性脂肪肝病/非酒精性steatohepatitis的钠-葡萄糖协同转运蛋白2抑制剂和肠泌素类药物：一项系统综述
Artur Macedo Cruz,Bruna Carolyne Venancio Lima,José Erivelton Souza Maciel de Ferreira et al.
Artur Macedo Cruz et al.
Background: In recent years, metabolic therapies originally developed to treat systemic metabolic disorders have been investigated as potential therapeutic strategies for Metabolic dysfunction-associated steatohepatitis (...
From authorisation to clinical practice: evolution of the use of biological medicines according to the SmPC and guidelines (2006 to 2025) [0.03%]
从批准到临床实践：根据SmPC和指南（2006-2025年）生物制剂的使用演变
B M F Penninx,C E M Hollak,S W Tas et al.
B M F Penninx et al.
Purpose: After the marketing authorisation of biologicals, uncertainty often remains regarding their real-world effectiveness, safety, and rational use. This study investigates how frequently the recommended use of biolog...
Curcumin versus placebo in benign prostatic hyperplasia: a systematic review and meta-analysis [0.03%]
姜黄素治疗良性前列腺增生的疗效和安全性：系统综述和.meta.分析
Diogo Souto Santana,Breno Cordeiro Porto,Rafael Baldissera Cardoso et al.
Diogo Souto Santana et al.
Background: Benign prostatic hyperplasia (BPH) is a highly prevalent condition among aging men and a major cause of lower urinary tract symptoms (LUTS). Although α1-adrenoceptor blockers and 5-alpha-reductase inhibitors ...
Secondary data analysis of Adverse Drug Reactions reported by healthcare professionals and patients: interventions to manage ADRs of ACE inhibitors and ARBs [0.03%]
医务人员和患者报告的不良事件 secondary 数据分析：管理ACE抑制剂和ARB类药品不良反应的干预措施
S H Spronk,J T H Nielen,L Heier et al.
S H Spronk et al.
Purpose: Prescribing cascades occur when an adverse drug reaction (ADR) of a first medication is treated with a second medication, potentially leading to polypharmacy and harm. While various interventions are recommended ...
Population pharmacokinetics of lumefantrine in pregnant and non-pregnant Nigerian women receiving efavirenz-based antiretroviral therapy [0.03%]
基于依非韦伦的抗逆转录病毒治疗对妊娠和非妊娠尼日利亚妇女鲁莫法内TRINE药代动力学的影响
Tawakalt Olamide Akinrinade,Ibrahim Adebayo Hassan,Adebanjo Jonathan Adegbola et al.
Tawakalt Olamide Akinrinade et al.
Purpose: Lumefantrine is a key partner drug in artemether-lumefantrine therapy, yet data describing its pharmacokinetics among women with efavirenz-based antiretroviral therapy remains limited. This study aimed to charact...
Influence of antihypertensive drug classes on circadian blood pressure patterns and left ventricular remodeling - a retrospective study [0.03%]
抗高血压药物种类对血压节律及左心室重构的影响——一项回顾性研究
Qin Ma,Shaoping Wang,Hua Chen
Qin Ma
Background: Circadian blood pressure (BP) abnormalities, including nondipping and reverse-dipping patterns, are increasingly recognized as major determinants of cardiovascular target-organ damage, independent of clinic BP...
Observational Study
European journal of clinical pharmacology. 2026 Jun 1;82(6):161. DOI:10.1007/s00228-026-04087-7 2026
Transdermal drug delivery systems in cancer therapy: advances, challenges, and future perspectives [0.03%]
癌症治疗中的经皮药物输送系统：进展、挑战与未来展望
Faezeh Arghidash,Amir Ali Judaki,Mohammad Moein Salehi Nejad et al.
Faezeh Arghidash et al.
Conventional cancer therapies, particularly oral and intravenous chemotherapy, are frequently associated with systemic toxicity, non-specific drug distribution, fluctuating plasma concentrations, and limited patient compliance. These drawba...
Efficacy and safety of Ongericimab in patients with hypercholesterolemia: a systematic review and meta-analysis [0.03%]
艾美赛珠单抗治疗高胆固醇血症患者的有效性和安全性：系统评价和.meta.分析
Ahmed L Youseif,Ahmed F Younis,Ziad W Elmezayen et al.
Ahmed L Youseif et al.
Background: Hypercholesterolemia represents abnormally elevated cholesterol levels and constitutes a major modifiable risk factor for cardiovascular diseases (CVDs). Low-density lipoprotein cholesterol (LDL-C) reduction r...