Sex differences in the meiotic behavior of an XX sex chromosome pair in males and females of the mole vole Ellobius tancrei: turning an X into a Y chromosome? [0.03%]
分子生态学视角下的性别反转：Ellobius tancrei中一对性染色体的分裂行为差异分析
Ana Gil-Fernández,Sergey Matveevsky,Marta Martín-Ruiz et al.
Ana Gil-Fernández et al.
Sex determination in mammals is usually provided by a pair of chromosomes, XX in females and XY in males. Mole voles of the genus Ellobius are exceptions to this rule. In Ellobius tancrei, both males and females have a pair of XX chromosome...
Deletion of the XIST promoter from the human inactive X chromosome compromises polycomb heterochromatin maintenance [0.03%]
人类失活X染色体的XIST启动子删除会破坏组蛋白多梳沉默异染色质结构
Natalia Westervelt,Andrea Yoest,Sadia Sayed et al.
Natalia Westervelt et al.
Silencing most gene expression from all but one X chromosome in female mammals provides a means to overcome X-linked gene expression imbalances with males. Central to establishing gene silencing on the inactivated X chromosome are the actio...
Ectopic expression of pericentric HSATII RNA results in nuclear RNA accumulation, MeCP2 recruitment, and cell division defects [0.03%]
HSATII卫星DNA转录产物的异位表达通过募集MeCP2导致核内RNA聚集和细胞分裂缺陷
Catherine C Landers,Christina A Rabeler,Emily K Ferrari et al.
Catherine C Landers et al.
Within the pericentric regions of human chromosomes reside large arrays of tandemly repeated satellite sequences. Expression of the human pericentric satellite HSATII is prevented by extensive heterochromatin silencing in normal cells, yet ...
Imaging assay to probe the role of telomere length shortening on telomere-gene interactions in single cells [0.03%]
一种检测端粒长度缩短对单细胞中端粒-基因相互作用影响的成像测定法
Ning Zhang,Yanhui Li,Tsung-Po Lai et al.
Ning Zhang et al.
Telomeres are repetitive non-coding nucleotide sequences (TTAGGGn) capping the ends of chromosomes. Progressive telomere shortening with increasing age has been associated with shifts in gene expression through models such as the telomere p...
Chromosome Y pericentric heterochromatin is a primary target of HSF1 in male cells [0.03%]
HSF1主要作用于男性细胞中的Y染色体臂间异染色质区域
Jessica Penin,Solenne Dufour,Virginie Faure et al.
Jessica Penin et al.
The heat shock factor 1 (HSF1)-dependent transcriptional activation of human pericentric heterochromatin in heat-shocked cells is the most striking example of transcriptional activation of heterochromatin. Until now, pericentric heterochrom...
Two telomeric ends of acrocentric chromosome play distinct roles in homologous chromosome synapsis in the fetal mouse oocyte [0.03%]
近端着丝粒染色体的两个端粒在小鼠胎儿卵母细胞同源染色体联会过程中扮演不同角色
Parinaz Kazemi,Teruko Taketo
Parinaz Kazemi
In mammalian oocytes, proper chromosome segregation at the first meiotic division is dictated by the presence and site of homologous chromosome recombination, which takes place in fetal life. Our current understanding of how homologous chro...
A deformation energy model reveals sequence-dependent property of nucleosome positioning [0.03%]
一个变形能量模型揭示了核小体定位的序列依赖性属性
Guoqing Liu,Hongyu Zhao,Hu Meng et al.
Guoqing Liu et al.
We present a deformation energy model for predicting nucleosome positioning, in which a position-dependent structural parameter set derived from crystal structures of nucleosomes was used to calculate the DNA deformation energy. The model i...
Limitation of current probe design for oligo-cross-FISH, exemplified by chromosome evolution studies in duckweeds [0.03%]
寡核苷酸交叉FISH设计的局限性——基于水鳖科植物染色体进化的研究实例
Phuong T N Hoang,Jean-Marie Rouillard,Jiří Macas et al.
Phuong T N Hoang et al.
Duckweeds represent a small, free-floating aquatic family (Lemnaceae) of the monocot order Alismatales with the fastest growth rate among flowering plants. They comprise five genera (Spirodela, Landoltia, Lemna, Wolffiella, and Wolffia) var...
Carlos García de la Vega,Rocío Gómez,Jesús Page et al.
Carlos García de la Vega et al.
spn-A/rad51 mutant exhibits enhanced genomic damage, cell death and low temperature sensitivity in somatic tissues [0.03%]
孢子母细胞/spi51突变体在体细胞组织中表现出增强的基因组损伤、细胞死亡和低温敏感性
Chaitali Khan,Sonia Muliyil,Champakali Ayyub et al.
Chaitali Khan et al.
Homologous recombination (HR) is one of the key pathways to repair double-strand breaks (DSBs). Rad51 serves an important function of catalysing strand exchange between two homologous sequences in the HR pathway. In higher organisms, rad51 ...