40 years of CENP-A: the foundation of a new era of centromere biology [0.03%]
CENP-A发现40年：新的中心粒生物学时代的基石
Simona Giunta,Tatsuo Fukagawa,Rachel J O&#x;Neill et al.
Simona Giunta et al.
Natalia Y Kochanova,Itaru Samejima,William C Earnshaw
Natalia Y Kochanova
In the 40 years since the discovery of the CENP proteins, many studies have examined the role of these proteins and their interactions with other chromosomal proteins of the centromere and beyond. Together, these studies have yielded vast a...
Molecular and bioinformatics analysis of long non-coding RNAs in cervical cancer [0.03%]
宫颈癌长非编码RNA的分子和生物信息学分析
Shalu Ranga,Ritu Yadav,Meenakshi B Chauhan et al.
Shalu Ranga et al.
Various long non-coding RNAs (lncRNAs) have indicated their role in different regulatory processes and therapeutics in cervical cancer (CC). This study aims to assess the gene expression and methylation status of LINC00518 & MAFG-AS1 in CC ...
The synaptonemal complex component corolla regulates meiotic crossover formation in Drosophila melanogaster [0.03%]
模式生物果蝇中冠状体通过调控交换形成影响专一 Crossing Over 的研究
Stefanie Williams,Grace McKown,Zulin Yu et al.
Stefanie Williams et al.
In Drosophila melanogaster females, as in most organisms, the segregation of homologous chromosomes in meiosis depends on the formation of crossovers between them. In most cases, crossovers require the synaptonemal complex (SC), a conserved...
Phosphorylation as a regulatory mechanism of HP1 protein multifunctionality [0.03%]
组蛋白变异体HP1蛋白质多功能性的磷酸化调控机制研究
James C Walts,Nicole C Riddle
James C Walts
The Heterochromatin Protein 1 (HP1) family proteins are key regulators of chromatin structure and genome function, acting as "reader" proteins that recognize and bind to histone H3 lysine 9 methylation (H3K9me). Beyond their canonical role ...
Philipp Oberdoerffer
Philipp Oberdoerffer
RAD18 promotes cell malignant behaviors of esophageal squamous cell carcinoma by modulating ATM/STAT3/PD-L1 [0.03%]
RAD18通过调节ATM/STAT3/PD-L1促进食管鳞癌恶性表型
Xianghui Yang,Qishi Song,Min Li et al.
Xianghui Yang et al.
Background: Esophageal cancer (EC) is still a difficult problem in medicine, depriving many patients of their lives every year. RAD18 and ATM were implicated in cancers including esophageal squamous cell carcinoma (ESCC)....
A tribute to 40 years of CENP-A & centromere pioneer Bill Earnshaw [0.03%]
纪念CENP-A和着丝粒先驱Bill Earnshaw教授发现四十周年
Yamini Dalal,Daniël P Melters,Genevieve Almouzni
Yamini Dalal
Regulatory effects of lncRNA PVT1 on transcriptome in human breast cancer MDA-MB-231 cell line determined by in silico analyses [0.03%]
长链非编码RNA PVT1对人类乳腺癌MDA-MB-231细胞系转录组的调控作用的计算分析研究
Zohreh Jahanafrooz,Nassim Ghaffari-Tabrizi-Wizsy
Zohreh Jahanafrooz
Overexpression or knockdown of a specific gene is usually helpful in understanding its underlying molecular mechanism. PVT1 gene is regarded as an oncogenic long non-coding RNA (lncRNA) in many cancers, including breast invasive carcinoma (...
Variable organization of repeats and hidden diversity of XY sex chromosomes in Pentatomidae true Bugs (Hemiptera) revealed through comparative genomic hybridization [0.03%]
通过比较基因组杂交揭示的pentatomidae_true_bug_(hemiptera)_中xy性染色体重复序列的多样组织和隐藏多样性
Diogo Milani,Vanessa B Bardella,Frederico Hickmann et al.
Diogo Milani et al.
Sex chromosomes have independently evolved in various species, displaying unique evolutionary patterns, including differentiation, degeneration, and repetitive DNA accumulation. Pentatomidae hemipterans are characterized by a highly conserv...