Using Synthetic DNA Libraries to Investigate Chromatin and Gene Regulation [0.03%]
利用合成DNA文库研究染色质和基因调控
Holly Kleinschmidt,Cheng Xu,Lu Bai
Holly Kleinschmidt
Despite the recent explosion in genome-wide studies in chromatin and gene regulation, we are still far from extracting a set of genetic rules that can predict the function of the regulatory genome. One major reason for this deficiency is th...
Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors [0.03%]
Tof1-Csm3和Mrc1连系建立因子通过重新启动复合物-粘着素相互作用提供
Sudikchya Shrestha,Masashi Minamino,Zhuo A Chen et al.
Sudikchya Shrestha et al.
The chromosomal cohesin complex establishes sister chromatid cohesion during S phase, which forms the basis for faithful segregation of DNA replication products during cell divisions. Cohesion establishment is defective in the absence of ei...
Chromosome stability @10! [0.03%]
染色体稳定@10!
K T Nishant,Kaustuv Sanyal
K T Nishant
A report on the 5th International Chromosome Stability Meeting, Thiruvananthapuram, India, Dec. 14-18, 2022. Keywords: ...
Emmely A Patrasso,Sweta Raikundalia,Daniel Arango
Emmely A Patrasso
Chemical modifications of nucleotides expand the complexity and functional properties of genomes and transcriptomes. A handful of modifications in DNA bases are part of the epigenome, wherein DNA methylation regulates chromatin structure, t...
Fluorescence-based super-resolution-microscopy strategies for chromatin studies [0.03%]
基于荧光的染色质研究超分辨率显微策略
Thomas C Q Burgers,Rifka Vlijm
Thomas C Q Burgers
Super-resolution microscopy (SRM) is a prime tool to study chromatin organisation at near biomolecular resolution in the native cellular environment. With fluorescent labels DNA, chromatin-associated proteins and specific epigenetic states ...
Establishment and inheritance of minichromosomes from Arabidopsis haploid induction [0.03%]
基于拟南芥单倍体诱导的最小染色体的建立与遗传
Ek Han Tan,Benny Ordoñez,Tejas Thondehaalmath et al.
Ek Han Tan et al.
Minichromosomes are small, sometimes circular, rearranged chromosomes consisting of one centromere and short chromosomal arms formed by treatments that break DNA, including plant transformation. Minichromosomes have the potential to serve a...
A cytological revisit on parthenogenetic Artemia and the deficiency of a meiosis-specific recombinase DMC1 in the possible transition from bisexuality to parthenogenesis [0.03%]
关于无性生殖枝角类 Artemia的细胞学再研究及其专性减数重组酶DMC1的缺乏在有性生殖到无性生殖转变过程中的作用缺陷
Lian-Ying Xu,Wen-Tao Wu,Ning Bi et al.
Lian-Ying Xu et al.
Although parthenogenesis is widespread in nature and known to have close relationships with bisexuality, the transitional mechanism is poorly understood. Artemia is an ideal model to address this issue because bisexuality and "contagious" o...
Are extraordinary nucleosome structures more ordinary than we thought? [0.03%]
我们之前认为的非同寻常的核小体结构原来是司空见惯吗？
Claris Y Y Chong,Lu Gan
Claris Y Y Chong
The nucleosome is a DNA-protein assembly that is the basic unit of chromatin. A nucleosome can adopt various structures. In the canonical nucleosome structure, 145-147 bp of DNA is wrapped around a histone heterooctamer. The strong histone-...
The launch of satellite: DNA repeats as a cytogenetic tool in discovering the chromosomal universe of wild Triticeae [0.03%]
微卫星在野生 Triticeae 染色体宇宙探索中的细胞遗传学工具作用及其应用效果初报
Pavel Yu Kroupin,Daniil S Ulyanov,Gennady I Karlov et al.
Pavel Yu Kroupin et al.
Fluorescence in situ hybridization is a powerful tool that enables plant researchers to perform systematic, evolutionary, and population studies of wheat wild relatives as well as to characterize alien introgression into the wheat genome. T...
A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase [0.03%]
一项基于全基因组的RNAi筛选发现了一些对在低温下培养的果蝇细胞增殖重要的基因，并且鉴定了其间的Ball/VRK蛋白激酶的作用
Anna Mendaluk,Emmanuel Caussinus,Michael Boutros et al.
Anna Mendaluk et al.
A change in ambient temperature is predicted to disrupt cellular homeostasis by affecting all cellular processes in an albeit non-uniform manner. Diffusion is generally less temperature-sensitive than enzymes, for example, and each enzyme h...