Kinesin-7 CENP-E mediates chromosome alignment and spindle assembly checkpoint in meiosis I [0.03%]
KINESIN-7 CENP-E介导减数分裂I期染色体排列与纺锤体组装检查点
Jing-Lian Zhang,Meng-Fei Xu,Jie Chen et al.
Jing-Lian Zhang et al.
In eukaryotes, meiosis is the genetic basis for sexual reproduction, which is important for chromosome stability and species evolution. The defects in meiosis usually lead to chromosome aneuploidy, reduced gamete number, and genetic disease...
Chromatin organization and behavior in HRAS-transformed mouse fibroblasts [0.03%]
HRAS转化的小鼠成纤维细胞中的染色质组织和行为
Aoi Otsuka,Katsuhiko Minami,Koichi Higashi et al.
Aoi Otsuka et al.
In higher eukaryotic cells, a string of nucleosomes, where long genomic DNA is wrapped around core histones, are rather irregularly folded into a number of condensed chromatin domains, which have been revealed by super-resolution imaging an...
Evi Soutoglou,Philipp Oberdoerffer
Evi Soutoglou
Histone FRET reports the spatial heterogeneity in nanoscale chromatin architecture that is imparted by the epigenetic landscape at the level of single foci in an intact cell nucleus [0.03%]
组蛋白FRET报告了由表观遗传景观在完整细胞核的单个焦点水平上赋予的纳米级染色质结构的空间异质性
Zhen Liang,Ashleigh Solano,Jieqiong Lou et al.
Zhen Liang et al.
Genome sequencing has identified hundreds of histone post-translational modifications (PTMs) that define an open or compact chromatin nanostructure at the level of nucleosome proximity, and therefore serve as activators or repressors of gen...
Dicentric chromosomes are resolved through breakage and repair at their centromeres [0.03%]
双着丝粒染色体通过其着丝粒处的断裂和修复得以解决
Diana Cook,Stanislav G Kozmin,Elaine Yeh et al.
Diana Cook et al.
Chromosomes with two centromeres provide a unique opportunity to study chromosome breakage and DNA repair using completely endogenous cellular machinery. Using a conditional transcriptional promoter to control the second centromere, we are ...
DNA replication and replication stress response in the context of nuclear architecture [0.03%]
染色体结构背景下的DNA复制与复制作应响应
Daniel González-Acosta,Massimo Lopes
Daniel González-Acosta
The DNA replication process needs to be coordinated with other DNA metabolism transactions and must eventually extend to the full genome, regardless of chromatin status, gene expression, secondary structures and DNA lesions. Completeness an...
Karyotypes of water frogs from the Pelophylax esculentus complex: results of cross-species chromosomal painting [0.03%]
Pelophylax_esculentus复合体水蛙的染色体核型：跨物种染色体原位杂交结果
Dmitrij Dedukh,Antonina Maslova,Ahmed Al-Rikabi et al.
Dmitrij Dedukh et al.
Amphibian species have the largest genome size enriched with repetitive sequences and relatively similar karyotypes. Moreover, many amphibian species frequently hybridize causing nuclear and mitochondrial genome introgressions. In addition,...
CTCF is essential for proper mitotic spindle structure and anaphase segregation [0.03%]
CTCF对于有丝分裂纺锤体结构和后期分离至关重要
Katherine Chiu,Yasmin Berrada,Nebiyat Eskndir et al.
Katherine Chiu et al.
Mitosis is an essential process in which the duplicated genome is segregated equally into two daughter cells. CTCF has been reported to be present in mitosis and has a role in localizing CENP-E, but its importance for mitotic fidelity remai...
H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos [0.03%]
Planococcus citri雄配子体中H3K9和H4K20甲基转移酶直接参与父本染色质异染色质化过程
Yakov A Osipov,Olga V Posukh,Darya A Kalashnikova et al.
Yakov A Osipov et al.
Using a new method for bulk preparation of early stage embryos, we have investigated the role played by putative Planococcus citri H3K9 and H4K20 histone methyl transferases (HMTases) in regulating heterochromatinization of the imprinted pa...
Nucleolin is required for multiple centrosome-associated functions in early vertebrate mitosis [0.03%]
nucleolin对于早期脊椎动物有丝分裂中多个中心体相关功能是必不可少的
Chandan Kumar,Sivaram V S Mylavarapu
Chandan Kumar
Nucleolin is a multifunctional RNA-binding protein that resides predominantly not only in the nucleolus, but also in multiple other subcellular pools in the cytoplasm in mammalian cells, and is best known for its roles in ribosome biogenesi...