Yoichi Asaoka,Shunsuke Tarumoto,Yoshinobu Hirose et al.
Yoichi Asaoka et al.
Since human inner ear hair cells do not regenerate, the current treatments of hereditary deafness depend on hearing aids or cochlear implant. However, uncovering the functions of genes responsible for hereditary hearing loss is not only use...
Phagophores originate from endoplasmic reticulum membranes in vasopressin neurons in a mouse model of familial neurohypophysial diabetes insipidus [0.03%]
在家族性神经垂体糖尿病利倍特症小鼠模型中，自噬体来源于血管加压素能神经元的内质网膜
Takashi Miyata,Daisuke Hagiwara,Ryosei Ashida et al.
Takashi Miyata et al.
Familial neurohypophysial diabetes insipidus (FNDI) is an autosomal dominant disorder caused by mutations in the arginine vasopressin (AVP) gene. In AVP neurons in a mouse model of FNDI, aggregates of mutant AVP precursors accumulate within...
MicroRNA-29b targets ADAM12 and 19 to regulate the extracellular matrix in lamina cribrosa cells [0.03%]
微小核糖核酸-29b通过靶向基质金属蛋白酶ADAM家族成员12和19调节筛板细胞外基质代谢
Aoife Smyth,Breedge Callaghan,Mustapha Irnaten et al.
Aoife Smyth et al.
Glaucoma remains the leading cause of irreversible blindness worldwide, with elevated intraocular pressure (IOP) being the only modifiable risk factor in primary open-angle glaucoma (POAG). Despite adequate IOP control, many patients contin...
Lenka Rouhová,Gabriela Krejčová,Ana Beatriz Barletta Ferreira et al.
Lenka Rouhová et al.
In the larvae of the mosquito Aedes aegypti, the three most important endocrine glands, the corpora allata (CA), the corpora cardiaca (CC), and the prothoracic gland (PG), together form the glandular complexes (GC). Using confocal laser sca...
Catecholaminergic system in the brain of the terrestrial slug Limax valentianus [0.03%]
生活在陆地上的蜗牛Limax valentianus的脑干黑质胆碱能系统研究
Ryota Matsuo,Aika Matsuki,Yuko Matsuo
Ryota Matsuo
Catecholamines, including dopamine, are thought to play important roles in the nervous system of mollusks. In the brains of the terrestrial gastropods, the procerebrum is the higher olfactory center involved in olfactory associative learnin...
Phagocytic hemocytes, independent of pericardial cells, modulate cellular immune responses on the dorsal vessel of mosquitoes, including the infection-induced reduction of the heart rate [0.03%]
蚊子中的吞噬血细胞（独立于心包细胞）调节背血管的免疫反应，包括感染诱导的心率降低现象
Cole J Meier,Shabbir Ahmed,Tania Y Estévez-Lao et al.
Cole J Meier et al.
Infection induces the aggregation of hemocytes on the dorsal vessel of mosquitoes. These hemocytes, called periostial hemocytes, phagocytose pathogens and produce immune factors on the abdominal portion of the dorsal vessel, called the hear...
Exploring the antiangiogenic effects of Phospholipases A2 from Bothrops diporus venom [0.03%]
博特普斯 Lancehead 蝮蛇毒中磷脂酶A2的抗血管生成效应探讨
Daniela J Sasovsky,Gabriela B Olea,Gonzalo Ojeda et al.
Daniela J Sasovsky et al.
Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is a crucial process in both physiological and pathological contexts, including cancer. Phospholipases A2 (PLA2s), enzymes found in snake venoms, have attracted...
Retraction Note to: Overexpression of miR-429 impairs intestinal barrier function in diabetic mice by down-regulating occludin expression [0.03%]
撤回 notice:miR-429过表达通过下调闭塞素表达损害糖尿病小鼠肠屏障功能
Tao Yu,Xi-Ji Lu,Jie-Yao Li et al.
Tao Yu et al.
Parvin is essential for indirect flight muscle (IFM) performance and Zasp52 localisation to the Z-disc in Drosophila melanogaster [0.03%]
Parvin对果蝇Drosophila melanogaster间接飞行肌肉（IFM）性能和Zasp52定位到Z-盘是必不可少的
Ushashi Ain,Benazir Fatma,Hena Firdaus
Ushashi Ain
The integrin-associated proteins (IAPs) function in a tightly regulated and coordinated manner to maintain the complex cytoarchitecture at the myotendinous junctions (MTJs) of Drosophila indirect flight muscles (IFMs). Parvin, a conserved b...
Differential expression of villin and advillin by neuroendocrine and tuft cells in the murine lower airways [0.03%]
小鼠下呼吸道神经内分泌细胞和刷状细胞中villin和advillin的差异表达
Wafaa Mahmoud,Alexander Perniss,Krupali Poharkar et al.
Wafaa Mahmoud et al.
Previous studies identified a rare cell type in the mouse tracheal epithelium with immunoreactivity to the microvillus protein villin (Vil1), which persisted in mice lacking tuft cells due to deletion of the transcription factor Pou2f3. Thi...