Comparative and immunohistochemical analyses on hepatic zonation in vertebrates with a special reference to evolution [0.03%]
以进化为重点的脊椎动物肝区带的比较与免疫组织化学分析
Nobuyoshi Shiojiri,Noriaki Ota,Haruka Hirose et al.
Nobuyoshi Shiojiri et al.
The mammalian liver lobules have zonation for various hepatic functions. It remains to be precisely determined which vertebrate taxa exhibit the hepatic zonation. There are two types of liver architectures in vertebrates: the portal triad t...
Comparative Study
Cell and tissue research. 2026 Mar 25;404(1):3. DOI:10.1007/s00441-026-04063-8 2026
Glucose transporter 1 deficiency impairs glucose homeostasis, cell proliferation, and morphology in human embryonic kidney cells 293 [0.03%]
葡萄糖转运蛋白1缺乏损害人胚肾细胞293的葡萄糖稳态、细胞增殖和形态学
Yash Mehta,Abraham Jacob Al-Ahmad
Yash Mehta
Glucose represents a major source of energy for mammalian cells. In such cells, glucose uptake is facilitated by the presence of various glucose transporters (GLUTs). Amongst the different GLUT isoforms expressed in mammalian cells, GLUT1 i...
Early intestinal barrier changes in A53T transgenic Parkinson's disease mice [0.03%]
A53T帕金森病转基因小鼠早期肠道屏障变化
Myat Noe Han,Olivia Artaiz,Matthew C Rowe et al.
Myat Noe Han et al.
Gut dysfunction commonly precedes motor symptoms in Parkinson's disease (PD), but the mechanistic sequence of gut versus brain pathology remains unclear. This work aimed to define the timing of intestinal barrier dysfunction relative to cen...
Fertility classification of the cow and peri-estrus sex-steroid hormones is associated with endometrial epithelial cell responses to conceptus and inflammatory signals [0.03%]
牛的生育分类和发情前期性类固醇激素与子宫内膜上皮细胞对概念uses和炎症信号的反应有关
Cecilia Constantino Rocha,Mariangela Bueno Cordeiro Maldonado,Fernando S Mesquita et al.
Cecilia Constantino Rocha et al.
In cattle, uterine receptivity to the embryo is programmed by intrinsic characteristics of the cow, the oscillation in sex-steroid hormones, and uterine health. The hypothesis is that fertility classification of cows and sex-steroid hormone...
Lgr5 positive stem cells sustain homeostasis and drive regeneration of the nasal septum olfactory epithelium [0.03%]
Lgr5阳性干细胞维系和支持鼻中隔嗅粘膜的稳态并驱动其再生
Suyeon Lee,Hyun-Yi Kim,Jonghoon Choi et al.
Suyeon Lee et al.
Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5)-expressing cells function as stem cells in various epithelial tissues. However, their specific roles in the olfactory epithelium (OE) are still not well understood. In this ...
Histological, ultrastructural, and single-cell profiling reveal immune-mediated remodeling in gallbladder inflammation [0.03%]
组织学、电镜及单细胞转录组分析揭示胆囊炎免疫重塑特征
Dmytro Vlasenko,Andrea Maccagno,Adriano Sanna et al.
Dmytro Vlasenko et al.
Gallbladder inflammation comprises distinct pathological entities, including acute, neutrophil-dominated injury and chronic, fibrotic remodeling. This study aimed to define the cellular and structural programs that characterize these two in...
Proteolytic dysregulation in the skin: insight from rare monogenic skin diseases [0.03%]
来自罕见单基因皮肤病的见解：皮肤蛋白酶失调
Zhongtao Li,Sheng Wang,Diana C Blaydon et al.
Zhongtao Li et al.
Proteases are essential enzymes that, through the breakdown of proteins, regulate many aspects of tissue homeostasis including barrier function, cellular signaling, and tissue repair mechanisms in organisms. Disease gene discovery in a numb...
Brain peptides in Alzheimer's disease - pathophysiology and therapeutic advances [0.03%]
阿尔茨海默病的脑肽研究-病理生理和治疗进展
Sonu Pahal,Arushi Gupta,Vivek Kumar et al.
Sonu Pahal et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and hallmark neuropathological features, including extracellular amyloid-β (Aβ) plaques and intracellular neurofib...
Three-dimensional structure and epithelial changes of the piriform sinus fistula in cotton rats [0.03%]
棉鼠梨状窝瘘的三维结构及上皮改变
Teppei Nakamura,Marina Hosotani,Osamu Ichii et al.
Teppei Nakamura et al.
Piriform sinus fistula (PSF) is a rare congenital anomaly derived from the third or fourth pharyngeal pouch. However, its developmental mechanisms remain poorly understood owing to the absence of suitable animal models. Cotton rats (Sigmodo...
TGFβ signaling regulates Col15a1 expression in fenestrated endothelial cells of the rat pituitary [0.03%]
TGFβ信号调节大鼠垂体窗孔内皮细胞中Col15a1的表达
Takashi Nakakura,Takehiro Tsukada,Takeshi Suzuki
Takashi Nakakura
Fenestrated capillaries in the anterior lobe (AL) of the pituitary gland are specialized for efficient hormone exchange and are surrounded by extracellular matrix-rich basement membranes (BMs). Although several collagens have been implicate...