Ana Clara de Oliveira,Ana Paula Macedo,Antonio Carlos Shimano
Ana Clara de Oliveira
The incidence of osteoporosis and related fractures increases significantly with age, impacting public health and associated costs. Postmenopausal osteoporosis results from increased bone resorption due to decreased estrogen levels. The end...
Saturation Effect of Lipid Accumulation Product (LAP) Index on Spinal Bone Mineral Density: A Population-Based Study [0.03%]
基于人群的横断面研究：脂质积累产物指数(LAP)对脊椎骨矿密度的影响存在饱和效应
Ting Sun,Xin Tie,Lu Liu et al.
Ting Sun et al.
Lipid accumulation product (LAP) has a positive effect on spinal bone mineral density (BMD). However, once LAP levels exceed 27.26, the rate of spinal BMD increase slow down or even decline. This indicates a biphasic relationship between li...
Bone Quality and Mineralization and Effects of Treatment in Osteogenesis Imperfecta [0.03%]
骨质量及矿化作用和成骨不全症的治疗效果
Barbara M Misof,Nadja Fratzl-Zelman
Barbara M Misof
Osteogenesis imperfecta (OI) is a rare congenital bone dysplasia characterized by high fracture rates and broad variations in clinical manifestations ranging from mild to increasingly severe and perinatal lethal forms. The underlying mutati...
Morinda Officinalis Polysaccharides Inhibit Osteoclast Differentiation by Regulating miR-214-3p/NEDD4L in Postmenopausal Osteoporosis Mice [0.03%]
牛膝多糖通过调控miR-214-3p/NEDD4L信号抑制绝经后骨质疏松小鼠破骨细胞分化
Hui Huang,Jian Chen,Xiaomei Lin et al.
Hui Huang et al.
To investigate the potential mechanism of Morinda officinalis F. C. How polysaccharides (MOPs) in regulating osteoclast differentiation and apoptosis through miR-214-3p and its target protein. Ovariectomy was performed in 8-week female C57B...
Deficiency of Trps1 in Cementoblasts Impairs Cementogenesis and Tooth Root Formation [0.03%]
成牙本质细胞中Trps1缺乏影响根袖和牙根形成
Kaoru Fujikawa,Mairobys Socorro,Lyudmila Lukashova et al.
Kaoru Fujikawa et al.
Cementum is the least studied of all mineralized tissues and little is known about mechanisms regulating its formation. Therefore, the goal of this study was to provide new insights into the transcriptional regulation of cementum formation ...
Skeletal and Non-skeletal Phenotypes in Children with Osteogenesis Imperfecta [0.03%]
儿童成骨不全症的骨骼和非骨骼表现特征
Juliana Marulanda,Jean-Marc Retrouvey,Frank Rauch
Juliana Marulanda
Although fractures are the defining characteristic of osteogenesis imperfecta (OI), the disorder affects many tissues. Here we discuss three facets of the OI phenotype, skeletal growth and development, skeletal muscle weakness and the denta...
Cardiac Biomarkers are Associated with Incident Fracture Risk in Advanced Chronic Kidney Disease [0.03%]
心脏生物标志物与慢性肾脏病晚期骨折风险的关系
Louise Aaltonen,Tapio Hellman,Roosa Lankinen et al.
Louise Aaltonen et al.
Cardiovascular disease is associated with increased fracture risk in the general population. Few data exist on the association between cardiovascular health and incident fracture risk in patients with advanced CKD, a high-risk population fo...
Validation of Ten Osteoporosis Screening Tools in Rural Communities of Taiwan [0.03%]
台湾农村社区10种骨质疏松症筛查工具的验证研究
Wen-Tung Hsieh,Tom Maarten Groot,Hung-Kuan Yen et al.
Wen-Tung Hsieh et al.
Patients with osteoporosis are at risk of fractures, which can lead to immobility and reduced quality of life. Early diagnosis and treatment are crucial for preventing fractures, but many patients are not diagnosed until after a fracture ha...
Developing Cut-off Values for Low and Very Low Bone Mineral Density at the Thoracic Spine Using Quantitative Computed Tomography [0.03%]
基于定量CT的腰椎骨密度分层的界值确定研究
Andia Cheneymann,Josephine Therkildsen,Laust Dupont Rasmussen et al.
Andia Cheneymann et al.
Osteoporosis is under-diagnosed while detectable by measuring bone mineral density (BMD) using quantitative computer tomography (QCT). Opportunistic screening for low BMD has previously been suggested using lumbar QCT. However, thoracic QCT...
Analyses of Osteogenesis Imperfecta in South Korea Using the Nationwide Health Insurance Service Claim Data: A Propensity Score-Matched Study [0.03%]
利用韩国全国健康保险服务理赔数据进行OI分析：倾向分值匹配研究
Sin Hyung Park,Ho Yoon,Siyeong Yoon et al.
Sin Hyung Park et al.
Osteogenesis imperfecta (OI) is the most common inherited form of bone fragility and includes a heterogeneous group of genetic disorders that most commonly result from defects associated with type I collagen. Although genetic analyses have ...