Regulation of Skeletogenic Pathways by m6A RNA Modification: A Comprehensive Review [0.03%]
m６A修饰调控成骨途径：综述
Ehsan Pashay Ahi
Ehsan Pashay Ahi
In the complex process of skeletal development, the significance of m6A RNA methylation-a predominant form of RNA modification-has not been fully explored. This review discuss how m6A RNA methylation plays an important, though not yet fully...
TGF-β Enhances Phosphate-Driven Calcification of Human OA Articular Chondrocytes [0.03%]
TGF-β增强磷驱动的人类骨关节炎软骨细胞钙化
Roderick H M J Stassen,Guus G H van den Akker,Marjolein M J Caron et al.
Roderick H M J Stassen et al.
The pathological relevance of articular cartilage calcification in osteoarthritis (OA) is becoming increasingly evident. We are only beginning to understand the pathobiological mechanisms that contribute to articular cartilage calcification...
Office Blood Pressure and Obesity in Children with X-Linked Hypophosphatemia [0.03%]
儿童X连锁低磷血症的办公血压和肥胖问题
Ineke Böckmann,Maren Leifheit-Nestler,Mirko Rehberg et al.
Ineke Böckmann et al.
X-linked hypophosphatemia (XLH) is the most common inherited form of hypophosphatemic rickets. Children with XLH have an increased risk of obesity, which may promote high blood pressure, but data on blood pressure in XLH are inconclusive. W...
Observational Study
Calcified tissue international. 2025 Mar 28;116(1):56. DOI:10.1007/s00223-025-01363-z 2025
Marie Teissonnière,Mathieu Point,Emmanuel Biver et al.
Marie Teissonnière et al.
Considerable progress has been made in the management of cancer patients in the last decade with the arrival of anti-cancer immunotherapies (immune checkpoint inhibitors) and targeted therapies. As a result, a broad spectrum of cancers, not...
Impact of Zoledronic Acid on Bone Mineral Density and Trabecular Score Following Denosumab Discontinuation in Older Adults in Long-Term Care [0.03%]
唑来膦酸对长期护理中老年人大肠杆菌停用后骨矿物密度和 trabecular 分数的影响
Nami Safai Haeri,Subashan Perera,Susan L Greenspan
Nami Safai Haeri
Discontinuation of denosumab can result in rebound bone loss and increased vertebral fracture risk. In residents of long-term care communities (LTCCs) with osteoporosis, there is limited data on managing the risks after discontinuation. We ...
Randomized Controlled Trial
Calcified tissue international. 2025 Mar 27;116(1):55. DOI:10.1007/s00223-025-01364-y 2025
Osteomesopyknosis: A Bone-Sclerosing Disorder that May be Confused with Bone Metastases [0.03%]
骨质硬化症：一种可能被误诊为骨转移的疾病
José A Riancho,Alvaro Del Real,Ana I Vega et al.
José A Riancho et al.
Sclerosing bone disorders encompass a range of genetic and acquired diseases. The potential for bone metastases is often a significant concern, especially when multiple discrete lesions are present. Several non-malignant disorders can also ...
Loss of the Ubiquitin-Associated Domain of sqstm1/p62 in Zebrafish Causes a Phenotype Resembling Paget's Disease of Bone [0.03%]
斑马鱼中与泛素关联域的丢失导致类似于骨Paget病的表型变化
Yentl Huybrechts,Raphaël De Ridder,Dylan Bergen et al.
Yentl Huybrechts et al.
The ubiquitin-binding protein p62, encoded by Sequestosome 1 (SQSTM1), is an essential molecular adaptor for selective autophagy. Heterozygous mutations deleting or disrupting the ubiquitin-associated (UBA) domain of p62 have been reported ...
Atractylenolide I Attenuates Glucocorticoid-Induced Osteoporosis via Inhibiting NF-κB Signaling Pathway [0.03%]
atractylenolide I通过抑制NF-κB信号通路减轻糖皮质激素诱导的骨质疏松症
Yamei Liu,Xiaoqi Deng,Chen Chen et al.
Yamei Liu et al.
Long-term treatment with glucocorticoids significantly impacts bone health, with glucocorticoid-induced osteoporosis (GIOP) being the most prevalent consequence. Previous studies have established that Atractylenolide I (Atr I) possesses ant...
Prevalence of Comorbid Hyperparathyroidism and Its Association with Renal Dysfunction in Asian Patients with X-Linked Hypophosphatemic Rickets/Osteomalacia [0.03%]
伴发甲旁亢及其与X连锁低磷性佝偻病/骨软化症患者肾功能不全的关联研究
Nobuaki Ito,Hee Gyung Kang,Toshimi Michigami et al.
Nobuaki Ito et al.
In patients with X-linked hypophosphatemic rickets/osteomalacia (XLH) in Asia, the current prevalence of hyperparathyroidism and its association with renal dysfunction have not been determined. We used patient data retrospectively collected...
Observational Study
Calcified tissue international. 2025 Mar 12;116(1):50. DOI:10.1007/s00223-025-01359-9 2025
The Relationship Between the Heterogeneity of Lumbar Vertebral Trabecular Bone Mineral Density Distribution and Osteoporotic Vertebral Fractures [0.03%]
腰椎松质骨矿物质密度分布异质性与骨质疏松性椎体骨折的关系
Yan Wang,Duoshan Ma,Chunyu Wang et al.
Yan Wang et al.
This study aims to investigate the relationship between the spatial distribution and heterogeneity of lumbar vertebral trabecular volumetric bone mineral density (vBMD) and osteoporotic vertebral fractures(OVF). This retrospective study inc...