Mineral Content and Extracellular Matrix Protein Expression in Mouse Growth Plates During Epiphyseal Fusion: An Observational Study [0.03%]
小鼠骨骺融合期间生长板中的矿化和基质蛋白表达:一项观察性研究
Xinhang Yu,Megumi Nakamura,Miyuki Mayanagi et al.
Xinhang Yu et al.
In humans, the growth plate cartilage is completely replaced by bone in late puberty, resulting in epiphyseal fusion. However, in rats and mice, commonly used experimental model systems, the growth plate does not fuse completely even after ...
Observational Study
Calcified tissue international. 2025 Jun 6;116(1):81. DOI:10.1007/s00223-025-01391-9 2025
Patterns of Bone Mineral Density Loss at Multiple Skeletal Sites Following Recent Menopause in Users and Non-Users of Menopausal Hormone Therapy [0.03%]
近期绝经后应用及未应用绝经激素治疗者的多个骨质疏松部位骨矿密度变化规律研究
Kara L Holloway-Kew,Amelia G Morse,Kara B Anderson et al.
Kara L Holloway-Kew et al.
Post-menopausal bone loss has been well described, however fewer studies have focussed on changes around the time of menopause. This study describes bone mineral density (BMD) loss following recent menopause, stratified by hormone replaceme...
Ranjitha Chandrashekar,Bharath K Mulakala,Manoj Gurung et al.
Ranjitha Chandrashekar et al.
Early-life resource limitation is one factor that could have a major impact on child health and development. Thus, using a rat model of limited bedding and nesting (LBN), we investigated the postnatal bone development, mineralization, and m...
Comparison of Type 2 Diabetes Risk in Osteoporosis Patients Treated with Denosumab or Alendronate: A Nationwide Cohort Study [0.03%]
一项全国队列研究:与阿仑膦酸钠相比,地舒单抗治疗骨质疏松症患者发生2型糖尿病的风险比较
Kyoung Jin Kim,Seol A Jang,Su Jin Kwon et al.
Kyoung Jin Kim et al.
Recent studies have suggested potential metabolic effects of anti-osteoporotic medications, but their impact on type 2 diabetes mellitus (T2D) risk remains unclear. This study investigated the incidence of T2D in patients with osteoporosis ...
Comparative Study
Calcified tissue international. 2025 May 30;116(1):78. DOI:10.1007/s00223-025-01385-7 2025
Geraniin Promotes Osteoblast Proliferation, Bone Formation, and Autophagy by Regulating the PI3K/Akt/mTOR Cascade to Improve Glucocorticoid-Induced Osteoporosis [0.03%]
牻牛儿芽素通过调节PI3K/Akt/mTOR信号通路促进骨形成、成骨细胞增殖和自噬以改善糖皮质激素诱导的骨丢失效应
XueGang Liang,QianPeng Ma,LiJuan Wang et al.
XueGang Liang et al.
Geraniin is a plant natural product that has been testified to perfect osteoporosis (OP). However, Geraniin's impacts on osteoblast autophagy and its latent molecular mechanisms remain uncertain. In this study, Geraniin's impacts on autopha...
Association of a Body Shape Index with Bone Mineral Density and Osteoporosis Among U.S. Adults: Evidence from NHANES [0.03%]
美国成人骨密度和骨质疏松症与身体形状指数关系——来自NHANES的证据
He-Gang Niu,Gao-Kai Hu,Tong Li et al.
He-Gang Niu et al.
Obesity significantly impacts bone health. The ABSI is an innovative metric for assessing obesity, offering greater accuracy than traditional measures such as body mass index and waist circumference in reflecting visceral fat accumulation. ...
The Association Between Two Different Non-invasive Advanced Glycation End Products and Osteoporosis in the Non-diabetic Population: A Cross-Sectional Study [0.03%]
两种不同非侵入性晚期糖基化终产物与非糖尿病人群骨质疏松症的关联:一项横断面研究
Yu-Yi Tian,Lu-Lu Xu,Ya-Qian Fu et al.
Yu-Yi Tian et al.
Advanced glycation end products (AGEs) are associated with osteoporosis (OP) in the diabetic population. However, their relationship with OP in the non-diabetic population remains unclear. This study aimed to investigate cross-sectional ass...
Grading Pseudo Fractures [0.03%]
伪骨折的评估
Sudhaker D Rao
Sudhaker D Rao
Transition Care for Young Persons with Rare Bone Mineral Conditions: A Consensus Recommendation from the ECTS Rare Bone Disease Action Group [0.03%]
罕见骨矿症青年患者的过渡护理:来自欧洲罕见骨病行动小组的共识建议
Corinna Grasemann,Joline Wernsmann,Natasha M Appelman-Dijkstra et al.
Corinna Grasemann et al.
Transition care (TC) is crucial for young persons with rare bone and mineral conditions (RBMCs) as they move from pediatric to adult healthcare. Effective TC prevents care disruptions and supports medical and psychosocial needs. However, ga...
Associations of Serum Vitamin D with Sarcopenia in Patients with Chronic Liver Disease: A Population-Based Cross-Sectional Study [0.03%]
血清维生素D与慢性肝病患者肌少症的相关性:一项基于人口的横断面研究
Xinxing Tantai,Zhang Wen,Shuyue Tuo et al.
Xinxing Tantai et al.
The association between vitamin D and sarcopenia in patients with chronic liver disease (CLD) has yet to be conclusively established, particularly in Western populations. We investigated the association between serum 25(OH)D levels and sarc...