Regular Proton-Pump Inhibitor Intake is Associated with Deterioration of Peripheral Bone Mineral Density, Microarchitecture, and Strength in Older Patients as Assessed by High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) [0.03%]
定期质子泵抑制剂的摄入与老年人外周骨密度、微结构和强度下降有关——由高分辨率外周定量计算机断层扫描（HR-pQCT）评估得出
Ursula Heilmeier,Alexandra Siegenthaler,Ursina Meyer et al.
Ursula Heilmeier et al.
Proton-pump inhibitors (PPI) are widely used among older adults and PPI intake has been associated with increased fracture risk. However, their association with bone microarchitecture and strength remains unclear as prior clinical PPI studi...
Birth Characteristics and Bone Mineral Density and Content in Young Adults: The HUNT Study, Norway [0.03%]
出生特征与青年成年人骨密度和骨量的相关性：来自挪威HUNT研究的证据
H T Holltrø,T I L Nilsen,B Schei et al.
H T Holltrø et al.
Purpose: To examine the association between birth characteristics and bone mineral density (BMD) and bone mineral content (BMC) in young adults. Methods: ...
Membrane Palmitoylated Protein 7 is Required for Osteogenesis and is Linked with Bone Mineralization and Osteoporosis: The Functional Evaluation of GEFOS GWAS Hit [0.03%]
膜棕榈酰化蛋白7对成骨作用是必需的并与骨矿化和骨质疏松症相关：GEFOS基因组研究结果的功能评估
Petra Malavašič,Jasna Lojk,Marija Nika Lovšin et al.
Petra Malavašič et al.
Genome-wide association studies have identified multiple loci associated with bone mineral density, a major determinant of osteoporotic fracture risk. At one such locus, genetic, bioinformatic, and zebrafish knockout data strongly prioritiz...
Differential Impact of Interferon-Based and Direct-Acting Antiviral Therapies on Bone Metabolism in Chronic Hepatitis C: Insights from Transcriptomic and Clinical Analyses [0.03%]
基于干扰素的直接抗病毒疗法对慢性丙型肝炎骨代谢的影响：来自转录组学和临床分析的启示
Yi-Lin Chiu,Tsai-Yuan Hsieh,Yu-Juei Hsu et al.
Yi-Lin Chiu et al.
Chronic hepatitis C (CHC) is a risk factor for hepatic osteodystrophy, increasing osteoporosis and fracture risks. While historical pegylated interferon/ribavirin (PEG-IFN/RBV) showed variable bone effects, the newer direct-acting antiviral...
Observational Study
Calcified tissue international. 2025 Oct 17;116(1):129. DOI:10.1007/s00223-025-01435-0 2025
Would Exosome Therapy be Effective for Bone Regeneration? Systematic Review and Meta-Analysis [0.03%]
外泌体疗法能有效促进骨再生吗？系统综述和.meta.分析
Virgínia Amorin Fróes de Moraes,Francisco Mônico Moreira,Carolina Dos Santos Santinoni et al.
Virgínia Amorin Fróes de Moraes et al.
Tissue engineering creates possibilities for promoting bone regeneration, which can culminate in an ideal therapy for treating bone defects. Considering its tools, especially exosomes (Exos), inferring its efficiency is fundamental for futu...
Correction: Evaluation of Low Alkaline Phosphatase Levels in Clinical Practice: Implications for Diagnosing Hypophosphatasia [0.03%]
关于评价临床低碱性磷酸酶水平及诊断低磷血症意义的更正：临床实践中低碱性磷酸酶水平评估及诊断低磷血症的意义再评价纠正意见
Gonul Buyukyilmaz,Serkan Bilge Koca,Refika Gören et al.
Gonul Buyukyilmaz et al.
Published Erratum
Calcified tissue international. 2025 Oct 11;116(1):126. DOI:10.1007/s00223-025-01434-1 2025
Letter to the Editor: Oral Semaglutide did not Significantly Improve Volumetric BMD in Overweight/Obese Type 2 Diabetes [0.03%]
读者来信：利拉鲁肽对超重或肥胖2型糖尿病患者骨密度无显著影响
Robin M Daly,David Scott,Jakub Mesinovic
Robin M Daly
Severe Osteoporosis in Larsen Syndrome-A Case Report of Bone Morphology and A Novel Filamin B (FLNB) Variant [0.03%]
Larsen综合征的重度骨质疏松一例报告：骨骼形态及新型肌球蛋白结合蛋白FLNB变异型
Trine Maxel Juul,Lisbeth Koch Thomsen,Christina Møller Andreasen et al.
Trine Maxel Juul et al.
Larsen syndrome is a rare genetic condition characterized by facial dysmorphism and skeletal deformities. It is caused by heterozygous pathogenic variants in the Filamin B encoding gene (FLNB). FLNB is a cytoskeletal protein that plays a ke...
Balanced Basic Multicellular Unit Activity in Cortical Bone of Ovariohysterectomized Rabbits [0.03%]
卵巢切除兔皮质骨平衡的基本多细胞单元活性
Lindsay L Loundagin,Kim D Harrison,David M L Cooper
Lindsay L Loundagin
It is well documented that the activation frequency of basic multicellular units (BMUs) is increased following menopause, but it is unclear if a negative BMU balance also contributes to osteoporosis-related bone loss or how remodeling dynam...
Real-World Effectiveness of Burosumab in Adults with X-Linked Hypophosphataemia (XLH) in the UK [0.03%]
布罗舒马斯特在英国成人X连锁低磷血症患者中的真实世界有效性研究
Judith Bubbear,Robin Lachmann,Elaine Murphy et al.
Judith Bubbear et al.
X-linked hypophosphataemia (XLH) is a genetic phosphate-wasting disorder caused by excess fibroblast growth factor 23 (FGF23), which leads to skeletal morbidities, pain, stiffness, and impairments in physical function and health-related qua...