SMAD2/3 signaling determines the colony architecture in a hydrozoan, Dynamena pumila [0.03%]
Dynamena pumila水母中SMAD2/3信号确定了子代的排列格局
Alexandra A Vetrova,Stanislav V Kremnyov
Alexandra A Vetrova
Most hydrozoan cnidarians form complex colonies that vary in size, shape, and branching patterns. However, little is known about the molecular genetic mechanisms responsible for the diversity of the hydrozoan body plans. The Nodal signaling...
WNT16 primer [0.03%]
WNT16引物
McLean H Williamson,Wilson K Clements
McLean H Williamson
Deciphering endocrine function of adipose tissue and its significant influences in obesity-related diseases caused by its dysfunction [0.03%]
解读脂肪组织的内分泌功能及其功能障碍引起的肥胖相关疾病中的重要作用
Feiyi Duan,Jiaoyan Wu,Jiayi Chang et al.
Feiyi Duan et al.
Current research has found that adipose tissue is not only involved in energy metabolism, but also a highly active endocrine organ that secretes various adipokines, including adiponectin, leptin, resistin and apelin, which are involved in t...
Dissecting the role of vitamin B12 metabolism in craniofacial development through analysis of clinical phenotypes and model organism discoveries [0.03%]
通过临床表型和模式生物研究解析维生素B12代谢在颅面发育中的作用
Briana E Pinales,Carlos E Palomino,German Rosas-Acosta et al.
Briana E Pinales et al.
Vitamin B12, otherwise known as cobalamin, is an essential water-soluble vitamin that is obtained from animal derived dietary sources. Mutations in the genes that encode proteins responsible for cobalamin uptake, transport, or processing ca...
Divergent functions of the evolutionarily conserved, yet seemingly dispensable, Wnt target, sp5 [0.03%]
进化上保守但却似乎可以没有的Wnt靶基因sp5的不同功能
Saurav Mohanty,Arne C Lekven
Saurav Mohanty
The activation of sp5 in response to Wnt/β-catenin signaling is observed in many species during axis patterning, neural crest induction, maintenance and differentiation of stem cells. Indeed, the conserved response of sp5 orthologs to Wnt-...
NEDD4's effect on osteoblastogenesis potential of bone mesenchymal stem cells in rats concerned with PI3K/Akt pathway [0.03%]
NEDD4通过PI3K/Akt信号通路影响大鼠骨髓间充质干细胞成骨分化潜能的作用机制研究
Bo Li,Shuang Zhang,Xiaoxian Yun et al.
Bo Li et al.
Neural precursor cell expressed developmentally down-regulated 4 (NEDD4) is an E3 ubiquitin ligase implicated in craniofacial development. Emerging evidence suggests that NEDD4 may down-regulates Akt signaling, a key element of the PI3K/Akt...
Diana Rigueur
Diana Rigueur
During the discovery of the Fibroblast Growth Factor superfamily, scientists were determined to uncover all the genes that encoded FGF proteins. In 1998, FGF16 was discovered with classical cloning techniques in human and rat heart samples....
Redefining retinoic acid receptor expression in zebrafish embryos using Hybridization Chain Reaction [0.03%]
利用杂交链反应重新定义斑马鱼胚胎中视黄酸受体的表达
Raèden Gray,C Ben Lovely
Raèden Gray
Retinoic Acid (RA) is the key signaling molecule during embryonic development with the RA pathway playing multiple roles in throughout development. Previous work has shown RA signaling to be key in development of the craniofacial skeleton. ...
Amber D Ide,Stephanie Grainger
Amber D Ide
WNT9 paralogues, WNT9A and WNT9B, are secreted ligands driving both the canonical (β-catenin dependent) and non-canonical (β-catenin independent) Wnt signaling pathways. These pathways play roles in cell fate determination, embryonic patt...
Samantha Bromley-Coolidge,Diego Iruegas,Bruce Appel
Samantha Bromley-Coolidge
The extracellular matrix (ECM) provides critical biochemical and structural cues that regulate neural development. Chondroitin sulfate proteoglycans (CSPGs), a major ECM component, have been implicated in modulating oligodendrocyte precurso...