Elisabet Stener-Victorin,Sofia Carlsson,Hannes Hagström et al.
Elisabet Stener-Victorin et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes, which affect approximately 38% and 10.5%, respectively, of adults globally, intersect critically in women through polyendocrine metabolic ovarian syndrome...
Early glycaemic exposure and cancer risk in people with newly diagnosed type 2 diabetes [0.03%]
新诊断的2型糖尿病患者早期血糖暴露与癌症风险的关系
Xinge Zhang,Aimin Yang,Hongjiang Wu et al.
Xinge Zhang et al.
Aims/hypothesis: The aim of this study was to determine whether overall and time-specific patterns of hyperglycaemia, particularly soon after diagnosis, are associated with incident cancer in adults with newly diagnosed t...
Diabetes-associated MYT1 and ST18 genes regulate human beta cell insulin secretion and survival via other diabetes risk genes [0.03%]
糖尿病相关基因MYT1和ST18通过其他糖尿病风险基因调控人类β细胞的胰岛素分泌及生存能力
Ruiying Hu,Nala Hamilton,Yu Wang et al.
Ruiying Hu et al.
Aims/hypothesis: Genetic and environmental factors work together to cause islet beta cell failure, leading to type 2 diabetes. How these factors are integrated to regulate beta cells remains largely unclear. Based on our ...
Olfactory dysfunction in obesity and type 2 diabetes: mechanistic insights from preclinical models [0.03%]
肥胖和2型糖尿病的嗅觉障碍:来自临床前模型的机制见解
Janice Bulk,Laura Casanueva Reimon,Sophie M Steculorum
Janice Bulk
Olfaction and its dysfunction have gained increasing interest across a broad spectrum of research areas including ageing and neurodegenerative and psychiatric disorders. In addition, olfactory dysfunction is increasingly recognised as a com...
Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes [0.03%]
一组病例描述中获得的1型糖尿病和饮食紊乱的临床及心理特征:T1DE特征
Divina Pillay,Nadine Paul,Amy Harrison et al.
Divina Pillay et al.
Aims/hypothesis: Type 1 diabetes and disordered eating (T1DE) is a common, complex comorbidity of type 1 diabetes with high morbidity and mortality risk. T1DE currently lacks a clear definition, diagnostic differentiation...
A randomised clinical trial testing the safety of and metabolic responses to short-term duodenal infusion of recombinant RORDEP1 in healthy men [0.03%]
评估杜氏肠灌注重组RORDEP1短期疗法安全性的随机临床试验
Joachim Gæde,Yong Fan,Liwei Lyu et al.
Joachim Gæde et al.
Aims/hypothesis: RUMTOR-derived peptides (RORDEPs) 1 and 2 are polypeptides synthesised by specific strains of the human gut commensal Ruminococcus torques. Preclinical studies have shown that RORDEPs lower blood glucose ...
Correction: SGLT2 inhibitor use and disparities in all-cause mortality in type 2 diabetes: insights from a multi-ethnic population [0.03%]
纠正:在第2型糖尿病患者中使用SGLT2抑制剂与全因死亡率差异的关系:来自多民族人群的启示
Lynne Chepulis,Han Gan,David Simmons et al.
Lynne Chepulis et al.
Published Erratum
Diabetologia. 2026 May 22. DOI:10.1007/s00125-026-06752-z 2026
Age-related patterns of cardiometabolic risk factors for complications in type 2 diabetes [0.03%]
2型糖尿病并发症的代谢性危险因素及年龄相关模式
Seyedeh Forough Sajjadi,Julian W Sacre,Sudhir Kowlessur et al.
Seyedeh Forough Sajjadi et al.
Aims/hypothesis: Beyond longer diabetes duration, uncertainty remains regarding the factors that contribute to a higher risk of developing complications in younger vs older people with type 2 diabetes. We investigated whe...
Effect of somatostatin receptor 2 antagonism on glucagon counterregulation during a hyperinsulinaemic euglycaemic-hypoglycaemic glucose clamp in adult men and women with long-standing type 1 diabetes: a randomised crossover phase 1 study [0.03%]
长效1型糖尿病成人男性和女性在高胰岛素血症正常血糖-低血糖糖钳夹期间, somatostatin受体2拮抗剂对胰高血糖素代偿反应的影响:一项随机交叉I期研究
Alexander Abitbol,Michael C Riddell,Susan Peers et al.
Alexander Abitbol et al.
Aims/hypothesis: The aim of this study was to determine the effect of a novel somatostatin receptor 2 (SSTR2) antagonist, ZT-01, on impaired glucagon counterregulation in hypoglycaemia and its safety in adults with type 1...