Age-independent immune subtypes in type 1 diabetes exhibit distinct post-onset progression rates and immunotherapeutic responses [0.03%]
1型糖尿病中的年龄独立的免疫亚型表现出不同的发病后进展情况和免疫治疗反应
Amina Bedrat,Nathan A Truchan,Tarun Pant et al.
Amina Bedrat et al.
Aims/hypothesis: The development of improved prevention and treatment strategies for type 1 diabetes requires a deeper understanding of its heterogeneity. Our aim was to measure immunological heterogeneity among individua...
Andreas Müller,Solange Aurrecoechea Duran,Patrícia I Santos et al.
Andreas Müller et al.
Islets of Langerhans constitute the endocrine component of the pancreas and comprise the main cell types responsible for the regulation of glucose homeostasis. Beta cells produce and secrete insulin, the principal hormone capable of lowerin...
Unhealthy fat distribution as a sex-specific predictor of declining hippocampus insulin sensitivity [0.03%]
不健康的脂肪分布作为性别特异性的预测因子预测海马体胰岛素敏感性下降
Leontine Sandforth,Ralf Veit,Jürgen Machann et al.
Leontine Sandforth et al.
Aims/hypothesis: Impairments in peripheral glucose metabolism and reduced brain insulin sensitivity are linked to an increased risk of both metabolic and neurodegenerative diseases. Brain insulin resistance represents a s...
Baseline and longitudinal joint associations of alcohol consumption and obesity with diabetes risk: evaluating multiplicative and additive interactions [0.03%]
饮酒和肥胖与糖尿病风险的基线和纵向联合关联：评估乘法和加性交互作用
Junghyun Yoon,Somin Jeon,Boyoung Park
Junghyun Yoon
Aims/hypothesis: The aim of this study was to examine whether the independent and joint effects of obesity and alcohol consumption on diabetes risk differ when exposures are assessed at baseline or as time-varying variabl...
GIP contributes to postprandial regulation of splanchnic blood supply in humans with type 2 diabetes: a randomised, single-blinded, placebo-controlled, crossover study [0.03%]
胃抑制多肽对2型糖尿病患者餐后内脏血流调节的影响：一项随机、单盲、安慰剂对照交叉试验
Rasmus S Rasmussen,Sophie W Nielsen,Lotte Alstrup et al.
Rasmus S Rasmussen et al.
Aims/hypothesis: In healthy lean humans, endogenous glucose-dependent insulinotropic polypeptide (GIP) contributes significantly to the postprandial increase in arteria mesenterica superior blood flow. The vascular biolog...
Correction: Analysis of glycaemic control with a connected smart pen cap in adults with type 1 diabetes: a randomised, open-label, parallel-group trial [0.03%]
对1型糖尿病成人使用智能笔帽连接装置控制血糖的分析：一项随机、开放标记、平行组试验的更正通知
Fernando Sebastian-Valles,Carolina Sager-La Ganga,Alicia Justel Enriquez et al.
Fernando Sebastian-Valles et al.
Published Erratum
Diabetologia. 2026 Jul 2. DOI:10.1007/s00125-026-06786-3 2026
History of infertility, risk of type 2 diabetes and HbA1c levels in the Nurses' Health Study II [0.03%]
护士健康研究第二期中的既往不孕史、2型糖尿病风险和HbA1c水平
Leslie V Farland,William J Degnan rd,Siwen Wang et al.
Leslie V Farland et al.
Aims/hypothesis: The aim of the study was to investigate the relationship between infertility history, the risk of type 2 diabetes and HbA1c levels. Metho...
Alexandra J Roth-Schulze,Katrina M Ngui,Guinevere Martin et al.
Alexandra J Roth-Schulze et al.
Aims/hypothesis: The breastmilk microbiome plays a crucial role in gut microbial colonisation and immune development, but little is known about how it is influenced by type 1 diabetes. ...
Remodelling of body composition surrounding the diagnosis of type 2 diabetes in three longitudinal cohorts [0.03%]
三项纵向队列中2型糖尿病诊断前后身体组成的变化
Jiaxing Du,Kun Zeng,Fen Zhang et al.
Jiaxing Du et al.
Aims/hypothesis: The temporal evolution of body composition surrounding type 2 diabetes diagnosis is unclear. To clarify this process, we characterised and compared the trajectories of BMI, boplledy roundness index (BRI) ...
Noora Said,Ian Jones,Emily K Anderson-Baucum et al.
Noora Said et al.
The COVID-19 pandemic was a dynamic and often confusing period for clinical and biomedical research. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread globally, knowledge accumulated rapidly through publications that we...