Polygenic background contributes to GCK-MODY clinical presentation and glycaemic variability [0.03%]
多基因背景对GCK-MODY临床表现和血糖变异性的贡献
Jacques Murray Leech,Ankit M Arni,V Kartik Chundru et al.
Jacques Murray Leech et al.
Aims/hypothesis: GCK-MODY (glucokinase MODY) causes lifelong, mild hyperglycaemia with high penetrance. Variation in glycaemic phenotype among carriers remains unexplained. We hypothesised that polygenic background contri...
Differential healthcare costs in individuals with type 2 diabetes and incident chronic kidney disease in Hong Kong: a latent class trajectory analysis [0.03%]
香港二型糖尿病并发慢性肾脏病患者的医疗成本差异：潜类轨迹分析
Yanrong Du,Minglu Zhang,Abby Q Y Li et al.
Yanrong Du et al.
Aims/hypothesis: Chronic kidney disease (CKD) represents a major and costly comorbidity in type 2 diabetes management. Identifying individuals with high healthcare costs due to CKD will support decision-making for early i...
The glycaemic response to morning fasted resistance exercise is more consistent than the response to afternoon fed resistance exercise for adults with type 1 diabetes: a randomised crossover comparison [0.03%]
与1型糖尿病成人相比，晨时空腹抗阻运动后的血糖反应比下午餐后抗阻运动后的血糖反应更一致：交叉随机对照试验
Reid D McClure,Alice L J Carr,Normand G Boulé et al.
Reid D McClure et al.
Aims/hypothesis: People with type 1 diabetes are recommended to modify insulin dosing and/or carbohydrate intake before, during and after exercise to manage blood glucose levels and prevent hypoglycaemia. An exercise stra...
Challenges in and opportunities for individualising diabetes technology: a position statement by the European Association for the Study of Diabetes (EASD) and the American Diabetes Association (ADA) Diabetes Technology Working Group [0.03%]
糖尿病技术的个体化面临的挑战和机遇：欧洲糖尿病研究协会（EASD）与美国糖尿病协会（ADA）糖尿病技术工作组立场声明
Daniela Bruttomesso,John R Petrie,Mark Evans et al.
Daniela Bruttomesso et al.
From fingerstick blood glucose monitoring and mechanical insulin pens in the 1970s to modern automated insulin delivery systems, rapidly progressing advances in diabetes technology are transforming management options for people with diabete...
Impact of canagliflozin on the cardiorenal effects of dietary sodium intake in type 2 diabetes: a post hoc analysis of the CREDENCE trial [0.03%]
卡格列净对2型糖尿病患者饮食钠摄入的心肾效应的影响：CREDENCE试验的事后分析
Martina Chiriacò,Domenico Tricò,Alberto Giannoni et al.
Martina Chiriacò et al.
Aims/hypothesis: Sodium-glucose cotransporter 2 (SGLT2) inhibitors provide cardiovascular and renal protection in type 2 diabetes and chronic kidney disease (CKD). Although both excess and restricted sodium intake are lin...
Integrated intraocular-plasma proteomics reveals conserved biomarkers for diabetic retinopathy progression: a multi-fluid biopsy study [0.03%]
整合的房水-血浆蛋白质组学发现糖尿病视网膜病变进展过程中保守的生物标志物：一种多体液活检研究方法
Jiahui Cao,Fenghao Liu,Huiqian Kong et al.
Jiahui Cao et al.
Aims/hypothesis: The aim of this study was to identify conserved biomarkers for diabetic retinopathy progression, addressing the lack of minimally invasive biomarkers to track the entire continuum of diabetic retinopathy....
Beta cell glucose sensitivity identifies clinical response to disease-modifying therapies initiated at stage 3 type 1 diabetes onset [0.03%]
β细胞葡萄糖敏感性可识别临床III型1糖尿病发病时启动的疾病修正疗法的临床反应
Carmella Evans-Molina,Stephen E Gitelman,Andrea Mari et al.
Carmella Evans-Molina et al.
Aims/hypothesis: At present, no disease-modifying therapies are available for individuals who have been newly diagnosed with type 1 diabetes, despite promising results from decades of clinical trials initiated at stage 3 ...
Alice L J Carr,Hannah Sutton,Rikke M Agesen et al.
Alice L J Carr et al.
Continuous glucose monitoring (CGM) has transformed diabetes management by providing continuous, real-time insights into glucose dynamics, while enhancing the lived experience of individuals with type 1 diabetes. In established type 1 diabe...
Early meal timing improves nocturnal glucose in pregnancies complicated by gestational diabetes [0.03%]
早孕期时间的进餐改善妊娠糖尿病患者的夜间血糖水平
Hannah A Cunningham,Lucy Ward,Matthew P Butler et al.
Hannah A Cunningham et al.
Aims/hypothesis: Gestational diabetes (GDM) results in adverse outcomes for the pregnant individual and neonate. Lifestyle modifications are first-line interventions used to achieve pregnancy-specific glucose targets. We ...