Exercise snacks performed in real-world settings reduce postprandial hyperglycaemia and glycaemic variability in individuals living with type 2 diabetes: a randomised crossover study [0.03%]
在现实环境中进行的锻炼“零食”可降低2型糖尿病患者餐后高血糖和血糖波动：一项随机交叉研究
Fiona J Babir,Alexis Marcotte-Chénard,Roderick E Sandilands et al.
Fiona J Babir et al.
Aims/hypothesis: Using a randomised, crossover design, we investigated whether exercise snacks could improve indices of glucose regulation assessed by continuous glucose monitoring, compared with an equivalent no-exercise...
Time delays between fingerstick glucose measurements and correctional insulin administration in the hospital: do they really matter? [0.03%]
血糖检测与医院中糖尿病患者胰岛素治疗之间的时间延迟有意义吗？
Kristen L Flint,Alana Fahey,Rebecca Longo et al.
Kristen L Flint et al.
Aims/hypothesis: Time delays exist between inpatient blood glucose measurements, insulin administration and meal timing. The clinical impacts of time delay on insulin dosing and hypoglycaemia risk have not been fully eval...
Inequalities in type 2 diabetes incidence in a multiethnic population: a cohort study investigating the impact of ethnicity, migration and mental health comorbidities [0.03%]
多民族人群中2型糖尿病发病率的不平等：一项关于种族、移民和精神健康合并症影响的队列研究
Diana Shamsutdinova,Daniel Stahl,Jayati Das-Munshi
Diana Shamsutdinova
Aims/hypothesis: Ethnic disparities in the incidence of type 2 diabetes mellitus are well documented in multiethnic urban populations, but the contributions of migration status and mental health are less well understood. ...
Age- and sex-specific trends in dementia mortality among people with and without diabetes: a multi-country population-based analysis [0.03%]
基于多国人群的分析：糖尿病患者和非糖尿病患者的痴呆症死亡率的性别和年龄特异趋势
Kanika Mehta,Jedidiah I Morton,Lei Chen et al.
Kanika Mehta et al.
Aims/hypothesis: Large-scale data on age- and sex-specific dementia mortality trends among people with diabetes remain limited, as most previous studies have been restricted to single countries or have not distinguished m...
Beta cell microRNAs function as molecular hubs of type 1 diabetes pathogenesis and as biomarkers of diabetes risk [0.03%]
β细胞微小核糖核酸作为1型糖尿病发病机制的分子中心和糖尿病风险生物标志物的功能研究
Farooq Syed,Preethi Krishnan,Garrick Chang et al.
Farooq Syed et al.
Aims/hypothesis: Clinically actionable biomarkers that accurately reflect the health status of the beta cell are needed to improve risk stratification and optimise the timing of interventions in type 1 diabetes. We hypoth...
Oral glucose absorption is enhanced in early metabolic dysfunction-associated steatotic liver disease [0.03%]
空腹高血糖有利于代谢性肝病早期吸收葡萄糖治疗
Domenico Tricò,Tongzhi Wu,Noemi Cimbalo et al.
Domenico Tricò et al.
Aims/hypothesis: Hepatic glucose flux plays a crucial role in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD), promoting de novo lipogenesis, inflammation and fibrosis. This study aimed...
ROMO1 and mitochondrial complex II/SDH are required for spare respiratory capacity and glucose homeostasis in mice [0.03%]
Romoglobin基因ROMO1及线粒体复合物II/琥珀酸脱氢酶对小鼠剩余呼吸容量和葡萄糖稳态是必需的
Lisa Wells,Qian Yang,Caterina Iorio et al.
Lisa Wells et al.
Aims/hypothesis: Reactive oxygen species modulator 1 (ROMO1) is a highly conserved inner mitochondrial membrane protein that senses reactive oxygen species and regulates mitochondrial dynamics. ROMO1 is required for mitoc...
Short-term modulation of human milk oligosaccharides in plasma and milk by glucose and insulin: insights into postpartum metabolic regulation [0.03%]
葡萄糖和胰岛素对人乳低聚糖短期调节的调控：产后代谢调节的新见解
Lukas Schönbacher,Anna M Walzl,Christina Stern et al.
Lukas Schönbacher et al.
Aims/hypothesis: Lactation is associated with reduced maternal risk of future diabetes mellitus and cardiovascular disease. Human milk oligosaccharides (HMOs), bioactive glycans produced in the mammary gland and already d...
Dietary effect on glucose homeostasis is modulated by a loss-of-function variant in the sucrase-isomaltase gene: a randomised, dietary crossover intervention in Inuit [0.03%]
膳食对糖代谢的影响由蔗糖-异麦芽糖酶基因的失活变异调控：在因纽特人中的饮食交叉干预研究结果
Ninna Senftleber,Marie Mathilde B Christensen,Bendix Carstensen et al.
Ninna Senftleber et al.
Aims/hypothesis: Homozygous carriers of a loss-of-function variant in the sucrase-isomaltase (SI) gene (c.273_274delAG) are unable to digest sucrose and parts of starch. The variant is common only in Indigenous Arctic pop...