Maternal pre-pregnancy BMI differentially regulates intracellular pH in human umbilical vein endothelium from gestational diabetes mellitus pregnancies, with alkalinisation-associated reduction of adenosine transport in normal weight pregnancies [0.03%]
母体孕前体重指数通过不同调节人脐静脉内皮细胞pH值来影响妊娠糖尿病，正常体重产妇表现出与细胞碱化相关的腺苷转运降低
Gonzalo Fuentes,Paola Valero,Marcelo Cornejo et al.
Gonzalo Fuentes et al.
Aims/hypothesis: Gestational diabetes mellitus (GDM) is associated with fetoplacental endothelial dysfunction, including impaired extracellular clearance of adenosine, a vasodilator, in HUVECs. This study investigated the...
Subtypes of newly diagnosed type 2 diabetes and risk of complications: analysis of electronic health records in the USA [0.03%]
美国电子健康记录中新诊断的2型糖尿病亚型与并发症风险的分析
Zhongyu Li,Star Liu,Joyce C Ho et al.
Zhongyu Li et al.
Aims/hypothesis: Data-driven subtyping of type 2 diabetes has not been translated into clinical practice due to the lack of routine fasting glucose and insulin measurements. We aimed to identify type 2 diabetes subtypes i...
Thromboxane signalling links immune activation to enhanced glucose uptake in skeletal muscle [0.03%]
血小板衍生四烷二醇信号通过免疫细胞活化促进骨骼肌葡萄糖摄取
Ahmed M Abdelmoez,Maxence Jollet,Xue Yu et al.
Ahmed M Abdelmoez et al.
Aims/hypothesis: Exercise elicits a spectrum of metabolic and inflammatory responses that are crucial for skeletal muscle adaptation and overall health, particularly in the context of metabolic diseases, yet the contribut...
Giuseppe Maltese,Janaka Karalliedde,Jugdeep Dhesi et al.
Giuseppe Maltese et al.
Over recent decades, the life expectancy of individuals with type 1 diabetes has steadily improved due to advances in therapies that enhance metabolic control alongside better prevention and management of complications. However, this extend...
Geospatial clustering of type 1 diabetes in Sweden: a cohort study based on all residential locations from birth to diagnosis [0.03%]
基于从出生到诊断的所有居住地位置的瑞典1型糖尿病地理空间聚类：队列研究
Samy Sebraoui,Oskar Englund,Fredrik Nyberg et al.
Samy Sebraoui et al.
Aims/hypothesis: Type 1 diabetes develops gradually, and previous exposures may influence incidence. We aimed to assess the geographical variation in type 1 diabetes incidence in Sweden by considering all residential loca...
Novel deuterium metabolic imaging technique reveals distinct patterns of postprandial hepatic glucose homeostasis in individuals with type 1 diabetes and healthy control individuals: a case-control study [0.03%]
新型氘代谢成像技术揭示1型糖尿病患者和健康受试者餐后肝脏葡萄糖稳态的差异：病例对照研究
Alessandro Brunasso,Naomi F Lange,Simone Poli et al.
Alessandro Brunasso et al.
Aims/hypothesis: Subcutaneous insulin delivery in individuals with insulin-deficient type 1 diabetes bypasses the portal circulation, disrupting the physiological porto-systemic insulin gradient and affecting postprandial...
Exercise in type 1 diabetes: real-world data on glucose levels and hypoglycaemia risk from over 420,000 exercise sessions [0.03%]
1型糖尿病运动与血糖关系：来自42万多次锻炼的血糖数据及低血糖风险分析
Josip Zivkovic,Michael Mitter,Delphine Theodorou et al.
Josip Zivkovic et al.
Aims/hypothesis: This large observational cohort real-world study explored the effects of three forms of exercise (walking [WALK], aerobic excluding walking [AER] and anaerobic [ANAER]) on glucose levels and hypoglycaemia...
Feasibility and performance of minimal-volume capillary blood screening for type 1 diabetes and coeliac disease autoantibodies across all age groups: the UNISCREEN population study [0.03%]
极小体积毛细血管血筛查第一型糖尿病和乳糜泻自身抗体的可行性和性能：UNISCREEN人群研究结果
Ilaria Marzinotto,Elena Bazzigaluppi,Cristina Brigatti et al.
Ilaria Marzinotto et al.
Aims/hypothesis: The UNISCREEN study investigated the feasibility of minimally invasive capillary blood sampling combined with novel antibody tests for population-wide screening of type 1 diabetes and coeliac disease auto...