Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/Vitronectin interaction [0.03%]
整合素α(v)β3与血纤蛋白的相互作用可诱导卵巢癌细胞增殖和迁移
Sandra Hapke,Horst Kessler,Birgit Luber et al.
Sandra Hapke et al.
During tumor metastasis, a fine-tuned balance between the formation and loosening of adhesive cell contacts has to occur, a process based on the regulated expression of integrins. Human ovarian OV-MZ-6 cancer cells express the integrin alph...
Angelika Bondzio,Petra Blankenstein,Siegfried Risse
Angelika Bondzio
Several activators of bovine leukemia virus (BLV) expression, including lipopolysaccharides, phorbol esters and calcium ionophores, are known to generate reactive oxygen species (ROS). Therefore the influence of H2O2 on BLV expression in tw...
Comparative Study
Biological chemistry. 2003 Jul;384(7):1063-72. DOI:10.1515/BC.2003.119 2003
Physarum polycephalum expresses a dihydropteridine reductase with selectivity for pterin substrates with a 6-(1', 2'-dihydroxypropyl) substitution [0.03%]
Physarum polycephalum 表达了一种具有6-(1', 2'-二羟基丙基)补骨脂异黄酮底物选择性的二氢蝶啶还原酶
Claudia Wild,Georg Golderer,Peter Gröbner et al.
Claudia Wild et al.
Physarum polycephalum is one of few non-animal organisms capable of synthesizing tetrahydrobiopterin from GTP. Here we demonstrate developmentally regulated expression of quinoid dihydropteridine reductase (EC 1.6.99.7), an enzyme required ...
Comparative Study
Biological chemistry. 2003 Jul;384(7):1057-62. DOI:10.1515/BC.2003.118 2003
A peroxidase from Lepista irina cleaves beta,beta-carotene to flavor compounds [0.03%]
Lepista irina 过氧化物酶裂解β,β-胡萝卜素生成风味物质
Holger Zorn,Sabine Langhoff,Manuela Scheibner et al.
Holger Zorn et al.
Extracellular liquid of the edible fungus Lepista irina was found to effectively degrade beta,beta-carotene, beta-lonone, beta-cyclocitral, dihydroactinidiolide, and 2-hydroxy-2,6,6-trimethylcyclohexanone were formed as volatile breakdown p...
Solubilisation and properties of the sialate-4-O-acetyltransferase from guinea pig liver [0.03%]
猪肝神经节糖脂4-O-乙酰转移酶的溶解及性质研究
Matthias Iwersen,Hiltrud Dora,Guido Kohla et al.
Matthias Iwersen et al.
The O-acetylation of sialic acids turns out to be one of the most important modifications that influence the diverse biological and pathophysiological properties of glycoconjugates in animals and microorganisms. To understand the functions ...
Transcriptional silencing of the TFPI-2 gene by promoter hypermethylation in choriocarcinoma cells [0.03%]
合胞素基因启动子高甲基化对其转录沉默的作用
Florent Hubé,Pascale Reverdiau,Sophie Iochmann et al.
Florent Hubé et al.
Tissue factor pathway inhibitor-2 (TFPI-2), a Kunitz-type serine proteinase inhibitor associated with the extracellular matrix, has been shown to reduce tumor invasion. In the present study we identified the presence of a complete CpG islan...
Interaction of maize chromatin-associated HMG proteins with mononucleosomes: role of core and linker histones [0.03%]
玉米染色质相关HMG蛋白与核小体的作用：核心组蛋白和连接区组蛋白的功能分析
Jacek Lichota,Klaus D Grasser
Jacek Lichota
Two groups of plant chromatin-associated high mobility group (HMG) proteins, namely the HMGA family, typically containing four A/T-hook DNA-binding motifs, and the HMGB family, containing a single HMG-box DNA-binding domain, have been ident...
Exploring the role of 5' alternative splicing and of the 3'-untranslated region of cathepsin B mRNA [0.03%]
猫氨酸B的mRNA的5'替代剪接和3' untranslated region的作用研究
Roman Zwicky,Kathrin Müntener,Gabor Csucs et al.
Roman Zwicky et al.
The cysteine peptidase cathepsin B is responsible for connective tissue breakdown in several diseases. The pathological expression of cathepsin B may depend on the structure of its mRNA. We investigated the translational efficiency of the c...
Are histones the targets for flavan-3-ols (catechins) in nuclei? [0.03%]
黄酮-3-醇（儿茶素）的作用靶点是细胞核内的组蛋白吗？
Jürgen Polster,Heike Dithmar,Feucht Walter
Jürgen Polster
Binding of flavan-3-ols to nuclei is characteristic of Tsuga canadensis (coniferous tree). This is achieved with the DMACA reagent (p-dimethylamino-cinnamaldehyde), which stains almost exclusively monomeric and oligomeric flavan-3-ols with ...
Yong-Won Kwon,Hiroshi Masutani,Hajime Nakamura et al.
Yong-Won Kwon et al.
Oxidative stress evokes various cellular events, including activation of transcription factors, apoptosis, and cell cycle arrest. Accumulating evidence shows that reduction/oxidation (redox) plays an important role in the regulation of apop...