Transcriptional silencing of the TFPI-2 gene by promoter hypermethylation in choriocarcinoma cells
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Tissue factor pathway inhibitor-2 (TFPI-2), a Kunitz-type serine proteinase inhibitor associated with the extracellular matrix, has been shown to reduce tumor invasion. In the present study we identified the presence of a complete CpG island region spanning ex... ...
