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e-ISSN:1424-8247

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共收录本刊相关文章索引10109
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Oana-Georgiana Oprea,Petru Fabian Lungu,Alexandru Ionut Chelaru et al. Oana-Georgiana Oprea et al.
Background/Objectives: Aggressive behaviour is commonly associated with neurodevelopmental disorders, such as autism spectrum disorder (ASD), and could be understood as a response to daily stress routines, which negatively impacts patients'...
Jun-Jie Shi,Jia-Quan Feng,Yuan-Hai Zou et al. Jun-Jie Shi et al.
Background: Propofol is used worldwide as a short-acting intravenous anesthetic in clinical practice; however, side effects such as injection pain and respiratory depression remain clinically relevant. Therefore, identification of safer pro...
Habip Burak Ozgodek,Ramazan Ince,Agah Abdullah Kahramanlar et al. Habip Burak Ozgodek et al.
Background/Objectives: Linezolid is an oxazolidinone antibiotic whose prolonged use is associated with peripheral neuropathy, hyperlactatemia, and metabolic acidosis. These adverse effects are primarily linked to the inhibition of mitochond...
Pathomporn Saisud,Orawan Monthakantirat,Prathan Luecha et al. Pathomporn Saisud et al.
Background/Objectives: Unpredictable chronic mild stress exposure is a primary driver of cognitive decline, largely mediated by hypothalamic-pituitary-adrenal (HPA) axis dysregulation and subsequent oxidative neurotoxicity. In traditional T...
Mateusz Matwiejuk,Agnieszka Mikłosz,Hanna Myśliwiec et al. Mateusz Matwiejuk et al.
Psoriasis is a chronic, inflammatory skin disease occurring worldwide that significantly affects patients' quality of life. This common skin condition is characterized by abnormal hyperplasia of keratinocytes, which leads to the formation o...
Mihaela Lipovanu,Anca Miron,Nina Filip et al. Mihaela Lipovanu et al.
Despite notable progress in drug discovery, cancer treatment remains hindered by limited therapeutic efficacy, poor target specificity, adverse effects, and the development of drug resistance. Molecular hybridization, which integrates two o...
Ibrahim A Alsarra,Mahima Sudhir Kolpe,Md Ataul Islam Ibrahim A Alsarra
Background: The extracellular-signal-regulated kinase (ERK) cascade regulates cell proliferation, differentiation, and survival, and ERK2 mediates substrate phosphorylation, influencing gene expression and cellular functions. Methods: In th...
Aneta Bednářová,Emma Szilassyová,Dominika Jarčušková et al. Aneta Bednářová et al.
The origins of major depressive disorder (MDD) are complex, involving both environmental influences and a substantial genetic contribution. Genetic polymorphisms have been implicated in modulating susceptibility, disease course, and treatme...