Torgny Stigbrand
Torgny Stigbrand
MicroRNA-638 inhibits cell proliferation by targeting suppress PIM1 expression in human osteosarcoma [0.03%]
microRNA-638通过抑制PIM1表达来抑制人成骨肉瘤细胞增殖
Xiao-Xu Wang,Jue Liu,Yi-Min Tang et al.
Xiao-Xu Wang et al.
MicroRNAs (miRNAs) are a type of small noncoding RNAs that often play important roles in carcinogenesis, but the carcinogenic mechanism of miRNAs is still unclear. This study will investigate the functions and the mechanism of miR-638 in os...
IL-17A produced by peritoneal macrophages promote the accumulation and function of granulocytic myeloid-derived suppressor cells in the development of colitis-associated cancer [0.03%]
腹腔巨噬细胞产生的IL-17A在结肠炎相关癌症发生发展过程中促进粒细胞来源的髓系抑制细胞的累积和功能
Yue Zhang,Juan Wang,Wenxin Wang et al.
Yue Zhang et al.
It is widely acknowledged that a close relationship is between inflammation and colon cancer. Interleukin (IL)-17A and myeloid-derived suppressor cells (MDSCs) play an important role in the development of colitis-associated cancer (CAC). Ho...
Effects of RNAi-mediated TUSC3 silencing on radiation-induced autophagy and radiation sensitivity of human lung adenocarcinoma cell line A549 under hypoxic condition [0.03%]
RNA干扰介导的TUSC3基因沉默对低氧条件下人肺腺癌A549细胞放射诱导的自噬及相关放射敏感性的影响研究
Ya-Guang Li,Nai-Xin Liang,Ying-Zhi Qin et al.
Ya-Guang Li et al.
This study examined the effects of RNAi-mediated TUSC3 silencing on radiation-induced autophagy and radiation sensitivity of human lung adenocarcinoma cell line A549 under hypoxic condition. Different CoCl2 concentrations were used to treat...
LncRNA HOTAIR promotes cisplatin resistance in gastric cancer by targeting miR-126 to activate the PI3K/AKT/MRP1 genes [0.03%]
长链非编码RNA HOTAIR通过靶向miR-126激活PI3K/AKT/MRP1基因促进胃癌顺铂耐药性
Jin Yan,Yini Dang,Shiyu Liu et al.
Jin Yan et al.
Altered expression of long noncoding RNAs (lncRNAs) has shown to associate with human cancer development and progression and drug resistance. LncRNA HOX antisense intergenic RNA (HOTAIR) regulates chromatin state and highly expressed in var...
FAT4 functions as a tumor suppressor in triple-negative breast cancer [0.03%]
FAT4在三阴性乳腺癌中作为肿瘤抑制因子的功能研究
Lingmi Hou,Maoshan Chen,Xiaobo Zhao et al.
Lingmi Hou et al.
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is often associated with biologic behavior with frequent distant metastasis. FAT tumor suppressor homolog 4 (FAT4), a cadherin-related protein, is involved ...
Fang Sun,Xia Xu,Xiaohong Wang et al.
Fang Sun et al.
Autophagy is an evolutionarily conserved lysosomal catabolic process used as an internal engine in response to nutrient starvation or metabolic stress. A number of protein complexes and an intricate network of stress signaling cascades impi...
Integrated analysis identified an intestinal-like and a diffuse-like gene sets that predict gastric cancer outcome [0.03%]
综合分析鉴定出两个胃癌预后相关的基因集：肠型和弥漫型特征相关基因集
Cheng Zhang,Li Min,Jiafei Liu et al.
Cheng Zhang et al.
The two major histological types of gastric cancer, intestinal and diffuse subtypes, have distinct epidemiological and pathophysiological features and were also suggested to be of diverse clinical outcomes. Although the gene expression spec...
Expression pattern of BCCIP in hepatocellular carcinoma is correlated with poor prognosis and enhanced cell proliferation [0.03%]
BCCIP在肝癌中的表达模式与不良预后和细胞增殖有关
Zhipeng Lin,Baoying Hu,Wenkai Ni et al.
Zhipeng Lin et al.
BCCIP was originally identified as a BRCA2- and CDKN1A- (Cip1/waf1/p21) interacting protein, also known as BCCIP. It has been reported to express in various types of cancers, including colorectal cancer (CRC), astrocytic brain tumors, and g...
A novel model for identification of prognostic indicator for clinical outcome of squamous cell lung carcinoma [0.03%]
一种新的预测性模型可判断肺鳞状细胞癌的预后指标
Kai Duan,Li Li,Xiao-Dong Tan et al.
Kai Duan et al.
Squamous cell carcinoma of the lung (SCCL) is the most common and aggressive lung tumor with poor clinical outcome. Identification and development of potential genes in prognostic process could be beneficial for clinical management. Sequenc...