MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2 [0.03%]
miR-122通过靶向Sprouty2促进肾癌细胞增殖
Zijie Wang,Chao Qin,Jing Zhang et al.
Zijie Wang et al.
MicroRNAs are short non-coding RNAs, which have been implicated in several biological processes. Aberrant expression of the microRNA miR-122 has frequently been reported in malignant cancers. However, the mechanism underlying the effects of...
Association of a common variant of SYNPO2 gene with increased risk of serous epithelial ovarian cancer [0.03%]
SYNPO2基因的常见变异与浆液性上皮卵巢癌风险增加相关性研究
Li Ma,Wei Zhang,Zhaoli Ding et al.
Li Ma et al.
In China, the majority of ovarian cancer patients (80%-90%) are women who are diagnosed with epithelial ovarian cancer. The SYNPO2 gene has recently been reported to be associated with epithelial ovarian cancer in Europeans. To investigate ...
MicroRNA-543 acts as a prognostic marker and promotes the cell proliferation in cervical cancer by BRCA1-interacting protein 1 [0.03%]
microRNA-543通过BRCA1相互作用蛋白1作为预后标志物并促进宫颈癌细胞增殖
Huimin Dang,Pengsheng Zheng,Yu Liu et al.
Huimin Dang et al.
Human cervical cancer is one of the most common malignancies worldwide. Recent studies have focused on microRNAs that play crucial roles in cancer development and progression of cervical cancer. In this study, we aimed to analyse the biolog...
Overexpression of junctional adhesion molecule-A and EphB2 predicts poor survival in lung adenocarcinoma patients [0.03%]
连接黏附分子-A和EphB2的过度表达可预测肺腺癌患者的不良预后
Chen Zhao,Aili Wang,Funian Lu et al.
Chen Zhao et al.
Junctional adhesion molecules are important components of tight junctions, and Eph/ephrin proteins constitute the largest family of receptor tyrosine kinases. Both junctional adhesion molecules and Eph/ephrin are involved in normal tissue d...
Downregulation of a novel long noncoding RNA TRPM2-AS promotes apoptosis in non-small cell lung cancer [0.03%]
新型长链非编码RNA TRPM2-AS低表达促进非小细胞肺癌凋亡的研究
Cheng Huang,Yingzhi Qin,Hongsheng Liu et al.
Cheng Huang et al.
Non-small cell lung cancer is one of the most common types of cancer, and the prognosis of non-small cell lung cancer is still poor. Recent evidence has proved that long noncoding RNA is involved in tumorigenesis. For non-small cell lung ca...
Extracellular vesicles: An overview of biogenesis, function, and role in breast cancer [0.03%]
细胞外囊泡：生物发生、功能及其在乳腺癌中作用概述
Quan Bin Zha,Yu Feng Yao,Zhao Jun Ren et al.
Quan Bin Zha et al.
Extracellular vesicles have emerged as important mediators of intercellular communication and play an active role in cancer, including breast cancer. Despite limited studies, initial observations suggest that these vesicles are important in...
Caveolin 1 expression favors tumor growth and is associated with poor survival in primary lung adenocarcinomas [0.03%]
caveolin 1的表达有利于肿瘤生长且与肺腺癌预后不良相关
Eleonora Duregon,Rebecca Senetta,Luca Bertero et al.
Eleonora Duregon et al.
Despite the consolidated clinico-pathological correlates of Caveolin 1 expression in non-small cell lung cancer, the available data on the role of Caveolin 1 in relation to proliferation, migration, and metastasis in lung adenocarcinoma cel...
Long leukocyte telomere length in prostate cancer patients at diagnosis is associated with poor metastasis-free and cancer-specific survival [0.03%]
前列腺癌患者诊断时较长的白细胞端粒长度与较差的无转移生存率和癌症特异性生存率有关
Ulrika Svenson,Göran Roos,Pernilla Wikström
Ulrika Svenson
Previous studies have suggested that leukocyte telomere length is associated with risk of developing prostate cancer. Investigations of leukocyte telomere length as a prognostic factor in prostate cancer are, however, lacking. In this study...
Reversal of hypermethylation and reactivation of glutathione S-transferase pi 1 gene by curcumin in breast cancer cell line [0.03%]
姜黄素通过逆转甲基化诱导乳腺癌细胞中谷胱甘肽S转移酶pi 1基因的再活化
Umesh Kumar,Ujjawal Sharma,Garima Rathi
Umesh Kumar
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor. Therefore, activation of tumor supp...
MicroRNA-223-3p inhibits human bladder cancer cell migration and invasion [0.03%]
微小核糖核酸-223-3p抑制人膀胱癌细胞迁移和侵袭
Ju Guo,Runfu Cao,Xingwei Yu et al.
Ju Guo et al.
The regulation of initiation and progression during carcinogenesis of bladder carcinoma is not completely elucidated. Dysregulation of microRNAs has been detected to play critical roles in the development of various cancers, including bladd...